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WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.
SYDNEY, Aug. 25 (Xinhua) -- Scientists in Australia have discovered a way of stopping mosquitoes carrying dengue virus, raising hopes for preventing the 50 million human cases of the disease every year, local media reported on Thursday.Groundbreaking experiments in Queensland have found a common insect bacteria, wMel Wolbachia, which can dramatically reduce the presence of dengue fever in mosquitoes.The research, led by Professor Scott O'Neill, Dean at Melbourne's Monash University, was published on Thursday in the prestigious journal, Nature.Australian researchers working on the Eliminate Dengue program aim to protect the mosquitoes themselves from dengue and so stop them transmitting the virus to humans."What the experiments have shown is that this strain of Wolbachia when it is put into mosquitoes really reduces the ability of the (dengue) virus to grow in the mosquito and if it can't grow, then it can't get transmitted in people," O'Neill told reporters.O'Neill said while it was too early to say if the experiments heralded the end of dengue fever, it was a major step towards that goal.In the past decade, there have been 2400 cases of dengue fever reported during 36 outbreaks in Australia.Dengue fever has become endemic in tropical regions, where it is spread by a specific type of mosquito that becomes infected after biting humans with the disease.Despite millions of people being infected with dengue each year, there is currently no way of stopping its rapid spread either by vaccines or controlling mosquito populations.Further trials will be conducted in Cairns in north Queensland over the coming wet season and approval is currently being sought for trials in Thailand, Vietnam, Brazil and Indonesia that will directly determine the effectiveness of the method in reducing dengue disease in human populations, according to Monash University.

WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.
OTTAWA, Sept. 29 (Xinhua) -- Climate change could cost Canada billions of dollars a year by the end of this decade, a government funded study group announced Thursday.The National Round Table on the Environment and the Economy said the cost of climate change for Canada could start at roughly 5 billion Canadian dollars per year in 2020 and increase to between 21 billion and 43 billion per year by 2050. Those costs would come from shoreline damage, public health problems, and disruptions to the economy.It also predicted a slight increase in deaths in major cities from heat and air pollution.The round table researchers estimated the cost of climate change is expected to be roughly 0.8 percent to 1.0 percent of GDP -- or 43 billion Canadian dollars a year -- by 2050, if the problem is allowed to worsen.But the report did not address possible benefits, such as reduced demand for hea
BEIJING, July 5 (Xinhuanet) -- Facebook CEO Mark Zuckerberg confirmed that he has signed up to Google+, the new social networking platform from Google, according to media reports Tuesday.Launched last month, Google+ is the Internet giant's latest foray into social networking.Zuckerberg confirmed that the profile with his name on Google+ belongs to him only, and said, "Why are people so surprised that I'd have a Google account?" Facebook CEO Mark Zuckerberg reacts after unveiling a new messaging system during a news conference in San Francisco, California November 15, 2010.In social networking field, it is rare for someone to join the rival's platform, therefore, Zuckerberg's move is considered strange.But interestingly, Zuckerberg has more followers than Google founders Larry Page and Sergey Brin, and even Vic Gundotra, the man behind Google+, with over 21,000 people.Besides Google+, Zuckerberg also has an account on Twitter, though it has not been updated for some time.
来源:资阳报