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Republicans suffered setbacks to court challenges over the presidential election in three battleground states on Friday as a national law firm that came under fire for its work for President Trump’s campaign withdrew from a major Pennsylvania case. The legal blows began when a federal appeals court rejected an effort to block about 9,300 mail ballots that arrived after Election Day in Pennsylvania. The judges noted the “unprecedented challenges” facing the nation during the COVID-19 pandemic. Meanwhile, a Michigan judge found no evidence of fraud in refusing to stop the certification of Detroit-area election results. And in Arizona, a judge dismissed a Trump campaign’s lawsuit seeking the inspection of ballots in metro Phoenix.President-elect Joe Biden is projected win at least 290 Electoral College votes, and could add to his lead depending on a hand recount in Georgia. Biden is leading Georgia by more than 12,000 votes. 944

Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said.  3711

RANCHITA, Calif. (KGTV) - Three people were found dead Sunday at the wreckage site of a plane crash that sparked a fire on Volcan Mountain that began Thursday night, according to the San Diego County Sheriff's Department.The people have not been identified. The victims will be airlifted out of the mountain once conditions are safe, the sheriff's office said. The winds were too high on Sunday to fly to the location.Because of the wildfire that burned at the site of the crash along with difficult conditions, investigators could not reach the site until Sunday.CalFire said the fire is now 100 percent contained and burned 12 acres. Crews will still be mopping up the crash site for several days, CalFire said.About 70 firefighters spent the night into Saturday fighting back flames.Friday, San Diego Sheriff's Department (SDSO) officials said they had located the wreckage of a "possible crash site" in the area, but could not reach it due to the fire. Cal Fire says the fire is burning “in an area that is steep and inaccessible to ground resources.”RELATED: Crews battling brush fire near Volcan Mountain in Julian area discover plane wreckage10News learned of the tail number of the reported plane involved late Friday. The tail number is linked to another incident in August 2013, where a twin-engine Beechcraft Duchess aircraft experienced a hard landing at Gillespie Field, collapsing a nose gear. 1445

Remote learning. More people are online and the hackers know that, according to David Anefils, the senior solutions engineer at supportclub.com."It's a major threat," he said. "It's very important for schools to take preventative measures to keep themselves as safe as possible, because people work 9 to 5, and all they do is a hack."Anefils said he's worked with some local schools."I would love to see the schools educate parents more on steps to take," he said. "The fact that the bad guy knows everybody is online."There are some steps you can take to keep your family safe while distance learning.Anefils said to make sure you provide physical supervision while your child is learning.Equally important is practicing good computer habits."By having good anti-virus to prevent malware from spying on your activity and computer updates on schedule," he said.Make sure to set up parental controls on devices being used. He also suggested calling your provider to make sure your home router is updated."A lot of hackers can take advantage of firmware not being updated and compromise your router," Anefils said.Make sure to update your computer regularly. Of the utmost importance, perhaps, is installing a virtual private network or VPN."It basically masks your router's IP address and allows you to surf the web without being spied on," he said.Make sure to avoid public WiFi without a VPN, if at all possible. Don't ever click on unknown links in emails. The bottom line, stick to what you know, making sure it is popular and secure."I feel safe on zoom ever since they made the latest updates," he said.This story was first reported by Tory Dunnan at WPTV in West Palm Beach, Florida. 1697

RAMONA, Calif. (KGTV) - The young man found shot to death in a Ramona home was identified by his roommate Monday as a resident of Ukraine.San Diego County Sheriff's deputies got a 911 call reporting Sunday at 8 p.m. reporting shots fired near the home on Wood Rock Lane. They found the victim dead inside.Four people live in the home, including Ben Ledbetter. He said the victim, a 20-year-old man, worked for Ledbetter's mobile detailing business for four years. Ledbetter believes he is being targeted and said someone killed his best friend out of anger."He's 100 percent good.  His heart is strong, his will is strong.  His attitude was positive.  You couldn't kill a better person.  He was the best person you could ever know," Ledbetter said.The victim's name is being withheld until his family can be notified.Deputies shut down the area near the home until 1 p.m. Monday to search for evidence. Ledbetter told 10News that detectives took his phone, truck and clothes as part of the investigation.Anyone with information on the incident is urged to contact sheriff’s Homicide Detail at 858-974-2321 or 858-565-5200.   1182