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LOS ANGELES, April 3 (Xinhua) -- People with lower levels of vitamin D are more likely to have stiffer arteries and an inability of blood vessels to relax, U.S. researchers have found.This finding also applies to people who are in general good health, according to researchers from the Emory University School of Medicine.The researchers presented their findings on Sunday at the annual American College of Cardiology meeting in New Orleans.Impaired vascular health in correlation with lower vitamin D levels contributes to high blood pressure and the risk of cardiovascular disease, the researchers say.The study involved 554 participants, with the average age of 47 and generally healthy.The average level of 25-hydroxyvitamin D (a stable form of the vitamin reflecting diet as well as production in the skin) in participants' blood was 31.8 nanograms per milliliter. In this group, 14 percent had 25-hydroxyvitamin D levels considered deficient, or less than 20 nanograms per milliliter, and 33 percent had levels considered insufficient, less than 30 nanograms per milliliter.The researchers monitored the ability of participants' blood vessels to relax by inflating and then removing a blood pressure cuff on their arms. To allow blood to flow back into the arm, blood vessels must relax and enlarge -- a change that can be measured by ultrasound. The researchers also made other measurements of smaller blood vessels and examined the resistance to blood flow imposed by the arteries.
WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.

BEIJING, March 21 (Xinhuanet) -- A new device is being developed by American engineers to ease pain of blood sugar testing in diabetics, according to foreign media report last week.The upcoming device is the research target of a team of engineers at Arizona State University. It is specifically designed for patients with type1diabetes and type2 diabetes, according to a report in the "Journal of Diabetes Science and Technology," The traditional method of testing blood sugar levels involves painful pricks on the fingers to draw blood for testing. The inconvenient and painful process may somehow leave diabetics lax in their testing. The blood sugar levels, when poorly controlled, are very likely to trigger complications including heart disease, kidney disease and retinopathy.Unlike the old testing method, the new device could help people keep track of their blood sugar levels without the need to break the skin. It draws tears to measures the blood sugar levels in the fluid and gives just an accurate reading of blood sugar levels. "This new technology might encourage patients to check their blood sugars more often, which could lead to better control of their diabetes by a simple touch to the eye." said Jeffrey T. LaBelle, developer of the device.The new testing device has drawn great interest from investors due to its promising prospects. However, it still awaits a significant amount of testing before it can hit the market.
XI'AN, Feb. 21 (Xinhua) -- Nearly 100 children were sickened by food poisoning Monday noon at a kindergarten in northwest China's Shaanxi Province.The accident occurred at Zhaocun Beibeile Kindergarten at Weiyang District of the provincial capital Xi'an City, where the children suffered from nausea and diarrhea after lunch, said a spokesman from the Weiyang District Government.The sickened children were rushed to five local hospitals for treatment, and their conditions were reported as not life threatening, the spokesman said.An initial inspection showed that their sickness was caused by nitrite intoxication, and the exact cause is under investigation.
GENEVA, May 3 (Xinhua) -- Roughly half to three quarters of adults aged between 18 to 65 years have had headache in the last year, a prevalent problem that went under-treated, the Geneva based World Health Organization (WHO) said in a report issued Tuesday.The report, named "Of Headache Disorders and Resources in the World 2011," regarded headache disorders as one of the most prevalent disorders of mankind.WHO estimated over 10 percent of the adult population suffered from migraine, and 1.7 to 4 percent of them were troubled frequently by headache on 15 or more days every month.Among all cases studied, the report said, on average only 10 percent were treated by neurologists, and the rates were even lower in Africa and South-East Asia.Three types of headache disorders were underlined as the most frequently seen, including migraine, tension-type headache and that caused by medication-overuse.The report concluded that given the very high indirect costs of headache, investment in health care related to headache treatment might be overall cost-saving to society.
来源:资阳报