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Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554
J.C. Penney has announced the 13 locations that will close permanently.The department store chain has already closed 154 stores after filing for Chapter 11 bankruptcy protection in May.In a blog post, the company continues to add stores and their locations set to close.Liquidation sales began on June 17, with liquidation at additional locations beginning on approximately July 3, the company said. 407

JERUSALEM (AP) — The international force that monitors the four-decade-old Israeli-Egyptian peace agreement has confirmed the deaths of eight peacekeepers in a helicopter crash in Egypt's Sinai region.The Multinational Force and Observers said six Americans, a French and a Czech were killed. It said a ninth peacekeeper survived and was evacuated for medical treatment.Names of the deceased are being withheld until next of kin are notified of the deaths.The force says “all indications” are that the crash was an accident, but it will still be investigated to determine a cause.The peacekeepers are responsible for monitoring troops levels and protecting free navigation in the area.Thirteen countries contribute troops to the force, with the U.S. providing the largest contingent.Acting Secretary of Defense Chris Miller issued this statement regarding the deaths: 875
Kroger Health recently received emergency approval for a COVID-19 at-home test collection kit.The kits will first be available to frontline employees at Kroger brand stores based on medical need, according to a press release from Kroger. The company hopes to expand the kits to other organizations and companies in the coming weeks.Kroger Health's collection sample test kits will be available to Kroger brand associates in Arizona, Colorado, Georgia, Indiana, Kansas, Kentucky, Michigan, Montana, Nevada, New Mexico, Ohio, Tennessee, Utah, and Virginia, according to the release.The U.S. Food and Drug Administration granted the emergency authorization on Tuesday. 673
Just weeks ahead of the midterm elections, U.S. election databases are coming under attack.A new report finds election hacking attempts have been building since April. One troubling note: the government does not know who is behind the attacks.“Well, it is worrisome. The more we know, the better,” says John Fortier, with the Bipartisan Policy Center. “But I also do think, in the world that we have, we are going to have unknown actors, whether foreign or domestic, making attempts to get into systems.”The good news is that, so far, Homeland Security says none of the attacks have been successful.Fortier thinks that's a sign of enhanced election security and better communication between election officials.“I think we are in a better place now to identify those threats and communicate those threats between federal and local and state election officials, and I think that's a step up,” Fortier says.As the midterms approach, the head of Homeland Security says the government will also be using other security tools, including sensors that allow federal officials to see inside state computer systems in order to detect if there are signs of hacking attempts.“Our network security sensors will cover 90 percent of registered voters,” says Secretary of Homeland Security Kirstjen Nielsen. “And on election day, we'll be in full force and hosting a virtual nationwide situation room to assist our partners.Experts continue to insist that voter databases, like registration information, is more at risk than hackers being able to change actual votes. 1559
来源:资阳报