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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.
UNITED NATIONS, Oct. 17 (Xinhua) -- China on Monday underlined the importance of safeguarding the peaceful use of outer space and preventing the weaponization of and an arms race in outer space, saying that "the outer space is the common wealth of mankind as the global public space."The statement came as Wang Qun, the Chinese ambassador for disarmament affairs, was taking the floor at the thematic debate on outer space at the First Committee of the UN General Assembly. The First Committee is in charge of disarmament and international security."The outer space is the common wealth of mankind as the global public space," Wang said. "The permanent peace of outer space is correlated to all nations' security, development and prosperity.""Meanwhile, with the growing reliance of mankind on outer space, the risk of the weaponization of and an arms race in outer space are on rise, and the uncertainties concerning outer space security are accumulating as well," he said. "Safeguarding the peaceful use of outer space and preventing the weaponization of and an arms race in outer space are common interest and obligations of all countries."In responding to the growing challenge for security in outer space, the international community also witnessed common grounds on opposing to the weaponization of outer space and advertising the Prevention of an Arms Race in Outer Space, he said.The General Assembly, for consecutive years, adopted " Prevention of an Arms Race in Outer Space" resolution by overwhelming majority of votes, calling for negotiations on an international legally-binding instrument on the prevention of an arms race in outer space at the Conference on Disarmament in Geneva."The mankind has marched into the 6th decade of outer space exploitation, and the manned space flight has made a history of 50 years," Wang said."Recently, China has successfully launched the Tiangong-1 ( Heavenly Palace 1) as a target spacecraft for rendezvous and docking experiment, which opens a new era of China's manned space flight, and also reflects that China is committed itself to the honorable objective of promoting the peaceful exploration and utilization of the outer space, maintaining peace and bringing benefit to mankind."
RIO DE JANEIRO, Oct. 21 (Xinhua) -- Representatives from 120 countries attending the WHO's World Conference on Social Determinants of Health on Friday pledged to maintain investments in healthcare to reduce social gap.A statement adopted at the conference urged governments to maintain international collaboration and promote equal access to healthcare regardless of wealth.Brazilian Health Minister Alexandre Padilha said the economic woes in many countries cannot be a reason to "diminish" their social policies."The crisis cannot be an obstacle, instead it must be an opportunity to consolidate social policies," he said.Brazilian Foreign Minister Antonio Patriota said at the conference that health was an issue related to sustainable development, which will be discussed at the UN's Rio +20 Conference in 2012."The conference that ended today is an important step toward Rio +20," he said.
BEIJING, Oct. 2 (Xinhua) -- Chinese archeologists have found evidence indicating that the mysterious ancient city of Loulan (Kroraina) once had highly-developed agricultural systems.Scientists from the Institute of Geology and Geophysics under the Chinese Academy of Sciences conducted remote sensing procedures, field investigations and sample testing in the area and found that there were once large tracts of farmlands in Loulan.The farmland featured regular and straight circumferences stretching for 200 to 1,000 meters as well as irrigation ditches running throughout, said Qin Xiaoguang, a member of the research team.Moreover, researchers found grain particles in the area's ground surface, which are very likely to be remains of crop plants, Qin said.These findings show that irrigation farming had been practiced in Loulan for at least 100 years, Qin said.Qin said they also found canal remains measuring 10 to 20 meters wide and 1.6 meters deep in the Loulan relics, indicating that the city, which is suspected of perishing in drought, was once rich in water resources.The ancient city was a pivotal stop along the famous Silk Road, but mysteriously disappeared around the third century AD.Previous historical records suggested that Loulan's economy was sustained by widespread agricultural activity, but no remains or other evidence had been found before the most recent discoveries.
BEIJING, Oct. 3 (Xinhuanet) -- Ziqian (not his real name, but an avatar he uses online) is in Paris working on his master's degree, but he stays in close touch with his contacts in China through Sina Corp's Weibo, a micro blog platform. It was a pleasant way to keep up with acquaintances. But that all changed when Ziqian quoted a blog post from an alumnus of his alma mater, Nanjing University, on July 5. It said the school did not organize students to sing Red songs ahead of July 1, the 90th anniversary of the founding of the Communist Party of China. Ziqian suddenly found himself inundated with comments from enraged bloggers whom he didn't know. He had lost all integrity, they said.Ziqian spent the whole night arguing with one netizen who assailed him with insults. He was left feeling tired and puzzled.He said he would have given up micro-blogging altogether as "purely useless", but he uses it to stay in touch with his girlfriend.Micro-blogging has been growing rapidly, dwarfing the many other forms of social networking that came into being only three or four years ago.Famed for spreading messages almost instantly and supervising the doings of agencies and organizations, micro blogs have already won some notable battles.In March, micro-bloggers persuaded the city of Nanjing, Jiangsu province, to spare 600 old trees that were to be cut down; they also organized assistance to earthquake victims in Japan.In July, they brought the Red Cross Society of China and other philanthropies under scrutiny.But, like everything in life, there is also a downside to micro-blogging.In the Weibo-dominated virtual world, Ziqian's experience has proved a common occurrence. A 28-year-old woman, surnamed Zhang, who declined to disclose her full name, works at a TV station in Jiangsu province. She recounted her recent encounter with online abusive remarks.After watching a popular talent show, Zhang wrote half-jokingly online - without using her real name - that the program was boring and lacked imagination. Regarding herself as an "industry insider", Zhang believed her reasoning had some objective basis.Nevertheless, she was soon confronted with a wave of criticism, some of it vulgar, saying she had no appreciation for the arts."I was very depressed by the comments. It's like you get kidnapped by mainstream opinion," she said. "I lost the desire to share my views with others.""I respect the freedom of speech doctrine, and everyone is allowed to publicize his or her thoughts," Zhang wrote in a separate post. "But don't hurl random assaults at others and take for granted that whatever you say is truth."Micro blogs have also made some ordinary people famous, though not in the way they would like.Zhang Mingyi, 22, is one such person.After appearing on a dating show on Shanghai-based Dragon TV, she said her micro blog inboxes were filled every day with letters lashing out at her, because of her open enthusiasm for Japanese culture and a failed marriage.Some netizens are relentless in their resentment of her. Even her micro blog followers received warnings to stay away from the "quisling". One such message read: "Go tell her to marry a Japanese man. Don't act so shamelessly in China".Similarly, Guo Meimei, now a household name, said she was being stalked and even threatened in early September, after she bragged in a micro blog post about her wealth and - untruthfully - claimed to hold a position at the Red Cross Society of China.Bloggers launched a vast campaign boycotting a song she released online and an online game she endorsed. They satirized her plastic surgeries and gossiped about her whereabouts. In a recent interview with China Daily, Guo said the animosity she stirred was so intense that she had even considered suicide."I feel like I am an enemy of the state," she said. "The truth is that I am just a stupid girl who did something really stupid. No matter what I do, nobody wants to forgive me."Celebrities are more likely to become the targets of the word-of-mouth maelstrom online. Yang Lan, for instance, a famous TV anchorwoman, came under tremendous pressure as bloggers dug into her connections with China-Africa Hope Project, an organization set up by a prominent philanthropist, Lu Junqing, that became controversial because he empowered his 24-year-old daughter to manage the charity's substantial donated funds.Bloggers questioned whether the purpose of Lu's initiative was charity or cashing in on donators. Rumors held sway on micro blogs.A recent study from University of Michigan suggests that it is crucial that people distinguish between the truth and unfounded rumors in online social media, where vast amounts of information are easily spread across a large network by sources of unverified authority.According to Xie Gengyun, author of the 2010 China Micro Blog Annual Report and deputy dean at the Arts and Humanities Research Institute at Shanghai Jiaotong University, micro blogs can generate and spread unfounded rumors, such as the "Shanxi earthquake" and "Louis Cha's death"."Micro-bloggers are currently the better-educated people in China. But users will soon include those at the grassroots level, and the function of micro blogs will change from celebrity-watching to online socializing and venting about life's disappointments," Xie said.China's Internet, with more registered users than any other nation, is a lively forum for public opinion, said Xinhua News Agency. But "concocting rumors is itself a social malady, and the spread of rumors across the Internet presents a massive social threat."The micro blog platform tends to breed more rumors and assaults than other channels because of the limited amount of characters each post can use, according to Xiong Yihan, a sociologist with Fudan University."The word limit has made it hard to present a balanced and fair opinion. Besides, posts with extreme views are more likely to be forwarded online, because they satisfy people's thirst for the unknown," Xiong said.Xiong said Internet companies should suspend the accounts of users who spread rumors or libelous statements.