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The US Food and Drug Administration approved a drug to return sexual desire to some women with low libido, the agency said Friday.The drug, bremelanotide, sold under the brand name Vyleesi by AMAG Pharmaceuticals, is an injection to be taken before sex. It's intended to treat women who are premenopausal and have hypoactive sexual desire disorder, where a lack of interest in sex may cause significant distress in a woman's life.It will be available in September, and the company has not yet determined pricing or reimbursement information, according to AMAG spokeswoman Sarah Connors."Most women who come into my office have no idea that there's this condition ... and that they are one of millions," said Sheryl Kingsberg, division chief of Behavioral Medicine at University Hospitals Cleveland Medical Center. Kingsberg was involved in the drug's clinical trials and has served as a paid consultant for the companies responsible for its marketing and development, AMAG and Palatin Technologies.Kingsberg, a clinical psychologist, said that "the impact of sexual dysfunction on a woman's self-esteem, on her body image, on her self-confidence and on her relationship is profound."Experts say the diagnosis is the most common type of sexual dysfunction among women, estimated to affect between 1308

TripAdvisor has defended itself against accusations of misleading travelers by failing to stop some of its highest ranked hotels winning their status with fake reviews.UK consumer group Which? Travel analyzed a total of almost 250,000 reviews for the 10 top-ranked hotels in 10 global tourist destinations, from Las Vegas to Cape Town. It found that one in seven of the hotels had "blatant hallmarks" of fake reviews, with others raising "serious concerns."But TripAdvisor called the analysis "flawed" and said its more sophisticated detection tools were able to weed out fraudulent feedback.Which? Travel said that when it reported 15 of the worst cases to TripAdvisor, the reviews giant -- now one of the world's biggest travel websites -- admitted that all but one of the hotels in question had been caught using fake reviews in the past year.Six had previously been penalized, and two had received a "red badge warning" -- where TripAdvisor warns users that the hotel is suspected of using fake reviews, and has "repeatedly failed to remedy its behavior and refuses to cooperate with TripAdvisor's investigators."Yet, Which? Travel said it found that the review patterns had continued unabated despite the measures, and the red badges had been removed.The group has accused TripAdvisor of a "lack of serious ongoing action to address repeated abuse of the system."It says that five-star reviews left by new users who have written no other reviews should be a red flag. Its analysis compared the proportion of first-time five-star reviews with that of first-time three-star reviews, which are less likely to be faked.In total, it studied 247,277 reviews."TripAdvisor's failure to stop fake reviews and take strong action against hotels that abuse the system risks misleading millions of travelers and potentially ruining their holidays," said Which? Travel's Naomi Leach.TripAdvisor has removed hundreds of reviews in light of the investigation, Which? Travel claimed."Striking" evidence of fake reviewsHotels in the Middle East had "striking" amounts of fake positive reviews, according to the research. TripAdvisor docked 730 five-star reviews of the "best" hotel in Jordan following the analysis -- but the hotel has not been given a red badge. It remains in the top 10 in the country.At the top-ranking hotel in Cairo, 79% of five-star reviews came from one-time contributors. Just 14% of three-star reviews came from similar accounts.The hotel has lost its status as a result of the reviews' deletion.Las Vegas was another hotspot for fake reviews. At two of the top-rated hotels, almost half the five-star reviews came from one-time contributors. For a competitor which did not arouse suspicion, the figure was just 3%.Some of the top-ranked hotels in London, Paris, Barcelona and Cape Town "gave reason for suspicion," the research showed, but failed to demonstrate the same patterns across the board.Repeat offendersTripAdvisor called the analysis "based on a flawed understanding of fake review patterns," adding that "it is simply far too simplistic to assume all first-time reviewers are suspicious."It said that Which? Travel did not have access to IP [internet protocol] information or location data, both of which TripAdvisor uses to detect fake reviews."We analyze hundreds of data points about each review -- most of which only we have access to -- and we combine that data with a wealth of knowledge and understanding of review patterns that our team of experts has gained from tracking hundreds of millions of reviews over a near 20-year period," said the company."This includes an ability to track and analyze first-time reviews in far more detail and with far more rigor than Which's team was able to do."Online reviews influence an annual estimated ￡23 billion ( billion) of booking transactions in the UK alone, according to the UK government."Sites like TripAdvisor must do more to ensure the information on their platforms is reliable," said Naomi Leach."If they continue to fall short, they should be compelled to make changes so holidaymakers are no longer at risk of being duped by a flood of fake reviews." 4152

The U.S. Food and Drug Administration is warning dog owners of a possible link between certain dog food brands and a serious form of canine heart disease.The 169

The owner of Schick razors needs to close the gap with Gillette, its biggest rival. So it's turning to new blood to make that happen.Edgewell Personal Care is buying the upstart razor maker Harry's, the two companies announced Thursday. The deal values Harry's at nearly .4 billion.Harry's started in 2013 and quickly expanded by selling low-priced razors online. Edgewell, meanwhile, owns some of the most established brands in the field — including Schick, which started in 1921. Edgewell also owns Wilkinson Sword, a major European brand that has been making razors since 1898.But Edgewell trails its main rival, Gillette, by a large margin. Gillette is a unit of Procter & Gamble, and accounted for about 10% of that company's .8 billion in revenue — about billion — last year. By comparison, Edgewell reported .2 billion in revenue during its most recent fiscal year.Sales for the first six months of this year fell 7% compared to a year earlier, Edgewell reported Thursday. But CEO Rod Little told investors that the company expects revenue to rise to .7 billion in its first full fiscal year after it acquires Harry's. The deal is expected to close early next year.Little said Edgewell was drawn to Harry's success with building a brand and marketing directly to consumers."We've been talking about it for a while," he said on an earnings call. "And when you look at what Harry's has done, we've looked at that from afar for a long time," he told investors."The deal also could help Harry's cut costs. Despite its success, Little said the business is only approaching the breakeven point this year.Investors didn't immediately embrace the purchase. Shares of Edgewell fell nearly 13% in midday trading Thursday.Harry's founders Andy Katz-Mayfield and Jeff Raider will stay on to run the combined companies' US business. Raider was also one of the founders of the eyeglass maker Warby Parker. The two of them had been friends since college.Harry's is not the first razor startup to be acquired by a more established company.In 2016, Unilever bought 2083

The Texas man who went viral for taking a tub of Blue Bell ice cream out of a grocery store freezer and licking it pleaded guilty to criminal mischief on Thursday. 175