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LONDON (AP) — Oxford University says trials of a coronavirus vaccine that it is developing with pharmaceutical company AstraZeneca will resume, days after being paused due to a reported side-effect in a patient in the U.K. The university said in large trials such as this “it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety.” It said globally 18,000 people have received the vaccine so far. Oxford insisted that it is “committed to the safety of our participants.” Pauses in drug trials are commonplace. The Oxford-AstraZeneca vaccine is seen as one of the strongest contenders among the dozens of coronavirus vaccines being tested. 728

LOS ANGELES (AP) — Some U.S.-based users of WeChat are suing President Donald Trump in a bid to block an executive order that they say would effectively prohibit U.S. access to the popular Chinese messaging app. The complaint was filed Friday in San Francisco and asks a federal court judge to stop Trump’s order from being enforced. It claims a ban would violate U.S. users’ constitutional rights. Trump has ordered sweeping but vague bans on transactions with the Chinese owners of WeChat and the TikTok app. He says they threaten U.S. national security. The Commerce Department is expected next month to reveal the types of transactions that would be banned. 669

LONDON — America’s top infectious disease has apologized for suggesting authorities in the United Kingdom rushed their authorization of a COVID-19 vaccine, saying he has “great faith” in the country’s regulators.Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, had sparked controversy with an earlier interview in which he said U.K. regulators hadn’t acted “as carefully” as the U.S. Food and Drug Administration.Fauci said late Thursday that he meant to say U.S. authorities do things differently than their British counterparts, not better, but his comments weren’t phrased properly.Fauci told the BBC: “I do have great faith in both the scientific community and the regulatory community at the U.K., and anyone who knows me and my relationship with that over literally decades, you know that’s the case.”After Fauci’s original comments, U.K. regulators went on the offensive. The Medicines and Healthcare Products Regulatory Agency said Friday that its personnel rigorously analyzed data on safety and effectiveness in the shortest time possible without compromising the thoroughness of their review.The agency's comments came as the Times newspaper reported that the agency’s chief executive would give a series of radio interviews so she can speak directly to people who may be concerned about being vaccinated.The media blitz comes after amid concerns that criticism of the approval process could undermine public confidence in the Pfizer/BioNTech vaccine, leading some individuals to shun shots. 1551

LONDON — A woman was killed and at least four other people were injured when a 65-foot crane collapsed in east London, authorities say.The London Fire Brigade says the crane fell onto a block of apartments under development and two houses on Wednesday. The brigade says the deceased woman was found on the first floor of one of the houses and confirmed dead at the scene.The London Ambulance Service has confirmed that two people have been taken to hospital with head injuries and two others were treated at the scene.The brigade’s assistant commissioner, Graham Ellis, says urban search and rescue crews were undertaking “a complex rescue operation” and using specialized equipment to search the properties, including a drone to provide aerial imagery.Crews and a team of specialist paramedics who work in hazardous environments were also at the scene in the Bow neighborhood. "This is a multi-agency response and is likely to be a protracted incident. I would ask people to avoid the area," said Ellis. 1012

Lockdown has been been the way of life for many months at the Central Union Mission. No residents are allowed in or out, as part of an effort to keep COVID-19 out of this homeless shelter.“That was a difficult choice for us, but our goal from the beginning was to provide a safe place for homeless men to be fed, sheltered and be COVID-free,” said Joseph Mettimano, president of the Central Union Mission. “And so not allowing new folks come in, that was heartbreaking.”It was heartbreaking but effective.Since the start of the pandemic, there have been no cases of COVID-19 at the shelter. It’s a feat they weren’t sure would be possible at the start of the pandemic.“We started working on this process very early with the same countermeasures that everybody else was doing: handwashing, sanitizing hand railings, all those types of things,” Mettimano said.That also included regular health screenings for residents and staff, all of which combined to create a coronavirus-free zone.“I think we've gotten close. The guys that are here in the facility over the last six months and encouraging one another to try to follow the protocols that the mission has [in] place,” said Jonathan Moncado, a resident at the shelter.While the shelter lockdown hasn’t been ideal for him and the other 100 or so men there, Moncado said there is a sense the sacrifice has been worth it.“We just are thankful to the staff that they've kept us safe for all these months,” he said. “There hasn't been one confirmed case or any deaths.”The same can’t be said everywhere.Across the country, people who are homeless haven’t completely avoided COVID-19.The most recent numbers show 400 of the 12,000 people who are homeless in Seattle tested positive for the virus, with at least two deaths. COVID-19 has infected 1,300 of the 66,000 people who are homeless in Los Angeles, with more than 30 deaths. Meanwhile, in Phoenix, about 500 of the estimated 7,400 tested positive, with at least 9 deaths.Yet, the numbers available may not be the most accurate. COVID-19 testing for those who are homeless isn’t widespread. In addition, the recorded deaths from coronavirus often don’t list someone’s housing situation, all of which could be skewing the numbers.Back at the Central Union Mission, there’s an even more pressing situation: a change in the weather.“With winter coming, we want to make sure that we can do all we can to help folks to prevent them from getting hypothermia,” Mettimano said. “So, we're going to have some difficult decisions coming our way.”It is a potential for tough decisions that may need to be made in the face of a devastating pandemic and unforgiving mother nature. 2675