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Moderna announced Thursday they have started giving teenagers their COVID-19 vaccine as part of their study on how the vaccine works in those under 18.Pfizer, the other vaccine maker with an emergency use request for their COVID-19 vaccine in adults before the FDA, started including teens in their trial in October.In the Moderna’s press release, they say the Phase 2/3 study of the mRNA vaccine is now underway and is being conducted on children between the ages of 12 and 18.“We are pleased to begin this Phase 2/3 study of mRNA-1273 in healthy adolescents in the U.S. Our goal is to generate data in the spring of 2021 that will support the use of mRNA-1273 in adolescents in advance of the 2021 school year,” said Stéphane Bancel, Chief Executive Officer of Moderna in a company statement. “We hope we will be able to provide a safe vaccine to provide protection to adolescents so they can return to school in a normal setting.”The Phase 2/3 study from Moderna is being done to test the safety and immunogenicity of the two-dose vaccine they submitted to the FDA for emergency use approval last month.They plan to enroll about 3,000 teenagers in the U.S. in the trial, with each receiving either a placebo or the vaccine in two doses, 28 days apart. 1262
NATIONAL CITY, Calif. (KGTV) — A nursing student's trip to a Starbucks in National City turned into an knock-down struggle and dramatic chase in pursuit of her laptop.With three finals next week, nursing student Jacqueline Ang spent the Friday using a computer at a library Bonita. "Grateful for the resource, but it's not the same," said Ang, who is wrapping up her first year in the nursing program at Southwestern College.It's not the same, because it doesn't have what she really needs: a year of notes. "It's devastating," said Ang.On Monday afternoon, she was studying with her MacBook Pro at a busy Starbucks on E. Plaza Boulevard. "Both earphones are in listening to lectures. One hand on my laptop, and the other hand taking notes," said Ang.Ang says she was at a table near the middle of the Starbucks when an older black teen in a hoodie walked in, and right up to her. He unplugged her earphones and turned to her computer. "Grabs it by the screen, closes it and starts running," said Ang.As the man ran off, Ang screamed to get someone's attention. She then took off after him. "When he's at the door, I'm able to grab him by the hoodie and bring him down. I'm saying, 'Please don't take it. Please don't take it,'" said Ang.On the ground, a struggle unfolded. Ang weighs just over 100 pounds."It's all that's on my mind. 'Omigod, everything I worked hard for is on that thing. I need that. I need to fight for that,'" said Ang.At some point during the struggle, she says the man was able to hand it off to another young man in a hoodie. Ang chased the other man, who slipped into a van in the parking lot. She was close behind, opening a side door. "I see three or four people in the van. I was holding onto the handle, running with the car as they're moving," said Ang.A bystander's short video shows her being dragged, before she let go. The incident left her with a sprained wrist and no laptop, but one big clue. Because Ang made the thieves' plans go awry, a witness was able to get the license plate number.National City Police asked 10News not to release the license plate in order to not endanger the investigation. A spokesperson says they see a handful of similar crimes every year, but haven't linked the suspects to any other incidents.A Gofundme campaign has been set up to help Ang purchase a new computer. 2344
Moderna says that it will file for Emergency Use Authorization for its COVID-19 vaccine candidate after a primary efficacy analysis showed it to be 94% effective in preventing the virus.In a press release on Monday, Moderna said that a primary efficacy study of its vaccine candidate showed it to be 94% effective in preventing COVID-19 infection and that no participants who received the vaccine developed a severe case of the virus.According to Moderna's press release, of the 30,000 participants who took part in a Phase 3 trial, 196 have since contracted the virus. Of those participants, only 11 had received the vaccine — the other 185 had received a placebo. Only 30 people who took part in the trial have developed a severe case of the virus, all of whom received a placebo shot.The findings are consistent with efficacy figures released by Moderna just weeks ago. Moderna is the second U.S. company to seek Emergency Use Authorization for a COVID-19 vaccine. Pfizer submitted its application earlier this month.Like Pfizer's vaccine, the Moderna vaccine requires two shots that need to be taken 28 days apart. It also needs to be stored at ultra-cold temperatures before injection.Health experts say it is encouraging that there are multiple COVID-19 vaccine candidates that are nearing authorization, as the public will be less reliant on one vaccine in the unlikely event of safety issues.Experts like Dr. Anthony Fauci have said that there is a chance that some Americans in high-risk populations could begin receiving the vaccine in the coming weeks. However, COVID-19 vaccines won't be available for widespread use until the spring.Moderna's vaccine was funded in part by country singer Dolly Parton, who donated million to COVID-19 research at Vanderbilt University earlier this year. 1810
Millions of small businesses are fighting off permanent closures, looking for every possible penny to help them stay afloat amid the pandemic. However, there is a little-known CARES Act rule that could net small businesses tens of thousands of dollars in just a few weeks, and it helps keep more people employed.Back in March, when Congress passed the CARES Act, most of the focus for businesses was on the billions of dollars allotted for Paycheck Protection Program (PPP) forgivable loans. Congress also included a temporary tax rule, at the same time, for businesses.“If you had a loss in 2018, 2019, or 2020, any of those years, you could carry it back up to five years to generate refunds,” said Chris Catarino, a CPA with the firm Drucker & Scaccetti in Philadelphia.Catarino explained that under the new rule, businesses can generate a tax refund by applying 2020 losses to taxes paid over the past five years, essentially making the tax burden in past years less, netting them the refund.Losses for 2020, though, can only be filed after Dec 31, 2020. However, the temporary rule also applies to 2019 and 2018. So, if a business had losses over those two years, they could carry back those losses to their respective five-year period and possibly generate a refund.Businesses can start filing for a refund on 2018 and 2019 losses now. Catarino explained they would have to file an amended return or 1045 form.“The 1045 is generally quicker,” said Catarino “The IRS is required to respond and process those within 90 days.”The tax refund, under the temporary net operating loss rule, could mean tens of thousands of much-needed dollars for some businesses. However, Catarino pointed out that the biggest refunds would be for businesses with the largest “swing” from the prior years.For example, take a business that did extremely well in 2019. It likely paid a high tax bill that year. Then, this year, it had a significant loss of business. That business could get most of the money it paid in taxes the year prior, possibly even all the money it paid but nothing more than was paid in taxes. The same principle applies to 2018 and 2019.“The idea that they could recoup some taxes that they already paid in the past, today, could really be significant,” said Todd McCracken with the National Small Business Association. “It could mean the difference between keeping your doors open or not.”Although the temporary tax benefit could save some businesses, there is concern that the businesses that may need it the most may not be aware of it.“It is the smallest companies that don’t know, that tend to deal with their taxes once a year,” said McCracken. "They don’t have an ongoing relationship with a CPA. They go have their taxes prepared in the spring and find out, ‘Wow, I could’ve had this benefit all along.’ Next spring, of course, could be too late.”It could be too late for many businesses, especially if another round of coronavirus-related closures occurs and a second stimulus package isn’t passed soon. 3031
Missouri Gov. Eric Greitens, who was indicted on a felony charge last month, is showing no sign that he will back down in the face of the scandal, running a radio ad this weekend touting his conservative mission and saying he "won't stop until the mission is complete."The ad, paid for by Greitens' campaign, does not explicitly address the controversy surrounding the Republican governor, but says liberals are "hell-bent on stopping his conservative reforms.""Even Satan's own lawyers from the Satanic Temple are suing Greitens," the narrator of the ad says in reference to a lawsuit by the Satanic Temple against the state of Missouri over its abortion laws.The governor's campaign has so far put ,000 behind the spot, according to one source with knowledge of the buy. It is set to air Thursday through Tuesday, coinciding with the Easter holiday."Eric Greitens is on a conservative mission for Missouri," the ad concludes, "and he won't stop until the mission is complete."Greitens was indicted in February on an invasion of privacy charge stemming from an extramarital affair he had in 2015. Greitens has admitted to the affair but denied breaking the law.The indictment against Greitens alleges he photographed a person in "full or partial nudity" without the person's knowledge or consent."Greitens then transmitted that image "in a manner that allowed access to that image via a computer," the indictment alleges.Greitens, who has been accused of blackmailing the woman with whom he was having an affair, has denied the charge, saying in a statement in February, "As I have said before, I made a personal mistake before I was Governor. I did not commit a crime."Democrats and some Republicans have called for his resignation and the Republican-led state House has opened an investigation into the charges against Greitens.Attorney General Josh Hawley's office has also announced that they are probing Greitens' veterans charity. 1948