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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462
SYRACUSE, N.Y. – A 95-year-old woman’s birthday party had to be canceled because of the coronavirus pandemic, but it didn’t stop her family from celebrating the milestone. The Syracuse, New York family had been planning Kathleen Byrne's party for months and relatives from across the country were set to attend the bash, but her health was more important. However, the family couldn’t let Kathleen’s birth go uncelebrated, so they brought the party to her front door and sang her “Happy Birthday” at a safe distance. “We had to keep our distance, but we couldn’t not see our best girl on her birthday!!!” wrote Sara Byrne, one of Kathleen’s granddaughters in an Instagram video that has now gone viral. In the video, family members and even some dogs are seen lined up in Kathleen’s yard with signs, serenading the grandmother of 22 grandchildren and 29 great-grandchildren.“I’m sorry we’re not all together, but you’re all altogether,” Kathleen can be heard saying in the video. At 95 years old, Kathleen is in an age group that is at a high risk of “severe illness” from the coronavirus, according to the 1119

Surgeon General Jerome Adams offered a stern warning to Americans on Monday, warning that the days ahead are crucial in the fight against COVID-19."I want America to understand: This week, it's going to get bad. We really need to come together as a nation," Adams said during an appearance on the Today Show.Adams urged Americans to practice proper social distancing and cited reports of 400
SEYMOUR — Hidden beneath the trees in a quiet Seymour, Indiana, neighborhood, Jessie Miligan showed where he picked up a baby, just hours old, with no mother in sight."There is a little bag over there. I see a little footprint pop out. I pick it up, I untie it and there is a little blanket covering its face," Miligan said. "So I pull it up and I am holding this little baby in a plastic bag, just back there. I don't know. I try not to judge, but there are way better ways of handling not being able to take care of a baby."It was an unusual sight to find in his neighborhood, or really anywhere."It is something that I never thought I would see in my life," Miligan said. "It is hard to believe that someone would tie a baby up and leave it outside. That baby more than likely would have froze to death. It's cold out."Miligan's mom, Angela Butler, first saw the baby while walking her dog, O.J. In disbelief, she said she went to grab her son and her phone to call 911 to get help for the baby."I told my boys, 'Go with me to make sure I am seeing what I am seeing,'" Butler said. "I had Jesse pick it up and, sure enough, it was a little newborn baby wrapped in a blanket. The blanket was covering its face and tied up, double-knotted, in a Walmart bag."Left alone and crying, Butler said just wrapping the baby in their arms while waiting for emergency crews to come provided some comfort to little one left to be found by a stranger."It was crying before we picked her up," Butler said. "And after we picked her up, she quit crying immediately."For this mother, it was a heartbreaking realization of what she just happened to stumble upon."It's sad knowing that the mother just dumped it off like it was a piece of trash," Butler said. "I don't see how anyone could do that to a child. Like, why would they put it in the woods? Just left it to die?"Seymour police announced Wednesday they identified and made contact with a person they wanted to interview in connection with the case, but there has not been any official update on the investigation.While it was by chance Butler came across the baby, she and her family left knowing they were able to change her future."It made me feel like I saved a life today," Butler said. "That that baby has a fighting chance to grow up and just to have a life." 2320
So now it is reported that, after destroying his life & the life of his wonderful family (and many others also), the FBI, working in conjunction with the Justice Department, has “lost” the records of General Michael Flynn. How convenient. I am strongly considering a Full Pardon!— Donald J. Trump (@realDonaldTrump) March 15, 2020 347
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