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As we're all focused on the current rollout of the COVID-19 vaccine, a technology known as thin-film freezing is getting a lot of attention. It's groundbreaking and could change the way we administer drugs or use medicine in general.You've probably heard about the need to keep the COVID-19 vaccine cold. It has to be so cold, in fact, that the shipment and transport are challenging. Well, what if that vaccine could be turned into powder?“What we’ve most recently been working on is the elimination of cold chain by storing as a powder, a dry powder where the drug is much more stable than if it was stored as a liquid or as a frozen liquid,” said co-inventor Dr. Robert Williams.Williams said it would eliminate the need for extreme cold storage and transport. The technology isn't new. He got a research grant and came up with it about 15 years ago.Williams, who is also a pharmacy professor at the University of Texas in Austin, said they were working on the technology and its multiple uses when the pandemic hit. And all of a sudden, they got a lot of attention.“We have published over 70 papers on the technology and using it for different products- it’s quite a mature process," Williams said. "We developed it because with other vaccines, the majority of the vaccine cost is in wastage because of this cold chain issue, so we published several key papers where we showed our thin-film freezing technology would protect vaccines - and you wouldn’t need cold chain storage.”Glenn Mattes, President, and CEO of TFF Pharmaceuticals added that the powders can be converted to topical preparations and they are currently working with the US Army to take some of the preparations and would then administer them directly through the eye.TFF is launching thin-film freezing into development through the FDA process. “I use the term ubiquitous because it is and disruptive because it is,” Mattes said. He added that they've explored their technology in the cannabinoid realm. But, as for the COVID vaccine, they're aiming for a second-generation usage.“To truly eradicate the pandemic, you have to have a global response," Mattes said. "The companies we’ve been speaking to certainly recognize the broad utilization of the technology but the application to the developing world, rural area, remote areas, where you can take a powder and inhale it or take the powder and reconstitute it has tremendous potential."Experts say it is only just the beginning as they launch their technology into a new world. 2511

AUSTIN, Texas – More people have now voted early in Texas for Tuesday’s general election than voted in total in the state during the 2016 election.As of Thursday, data on the secretary of state’s website shows a total of 9,009,850 Texans had voted either by mail or in person, and there’s still one more day of early voting in the state.That number surpasses the record-breaking 8,969,226 votes that were cast in the state during the 2016 election.The high voting turnout signals that Texas may be a true battleground state in the 2020 election.Democrats are trying to take advantage of the enthusiasm to flip the traditionally Republican state and collect its 38 electoral votes. Though, pollsters at FiveThirtyEight show President Donald Trump is still “slightly” favored to win the state, with a 66% chance. That’s according to the website’s forecast, which is based on polling averages.Still, Joe Biden's campaign appears to see potential in Texas and is even sending running mate Kamala Harris to the state Friday to campaign in the final leg of the presidential race. 1081

As we drive down the eerily deserted Hong Kong-Zhuhai-Macau Bridge, the murky waters of the Pearl River Delta stretch as far as the eye can see. There is no land in sight.Spanning 34 miles (55 kilometers), this is the longest sea-crossing bridge ever built. Guo Xinglin, assistant director and senior engineer at the Hong Kong-Zhuhai-Macao Bridge Authority, meets us half way along. As we are buffeted by a strong wind, the tough conditions his construction crew experienced, as they perched on precarious platforms, working miles from land and high over the water, are evident.Guo is visibly proud of his country's monumental achievement. 647

ATLANTA (AP) — The funeral for the Rev. C.T. Vivian, an early and key adviser to the Rev. Martin Luther King, is to be held Thursday. Because of the coronavirus outbreak, the service will be private and open only to family, according to a news release from the C.T. and Octavia Vivian Museum and Archives. It's scheduled for 11 a.m. Thursday at Providence Missionary Baptist Church in Atlanta, and will be streamed live online and broadcast by WSB-TV. Vivian died at home in Atlanta of natural causes at age 95 on Friday, the same day that fellow civil rights leader U.S. Rep. John Lewis died. 601

ATLANTA, GA. – The prevalence of adult obesity is increasing in the United States, according to new data from the Centers for Disease Control and Prevention (CDC).The CDC said Thursday that its 2019 Adult Obesity Prevalence Maps show that 12 states now have an obesity prevalence at or above 35%. Those states include Alabama, Arkansas, Indiana, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Oklahoma, South Carolina, Tennessee, and West Virginia. This is up from nine states in 2018 and six states in 2017.The data also shows that racial and ethnic disparities still persist across the nation.A total of 34 states and Washington D.C. had an obesity prevalence of 35% or higher among non-Hispanic Black adults, 15 states had a prevalence of 35% or higher among Hispanic adults, and six states had a prevalence of 35% or higher among non-Hispanic white adults.Addressing the prevalence of obesity in America is more important than ever, because the CDC says obese adults are at heightened risk for severe outcomes from COVID-19. It increases the risk of severe illness, hospitalization, and death.The CDC says obesity also disproportionately impacts some racial and ethnic minority groups who are also at increased risk of COVID-19.“These disparities underscore the need to remove barriers to healthy living and ensure that communities support a healthy, active lifestyle for all,” wrote the CDC in a press release.While system and environment changes can take time, officials say Americans can take small steps now to maintain or improve their health and protect themselves during the pandemic.“Being active and eating a healthy diet can support optimal immune function and help prevent or manage chronic diseases that worsen outcomes from COVID-19,” the CDC wrote. “These actions, as well as getting enough sleep and finding healthy ways to cope with stress can help with weight maintenance and improve overall health.” 1934