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Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

Home prices hit a new all-time high this month. New numbers out today from Realtor.com show the national median listing price is at 9,000, a ,000 increase over last year.But there aren't a lot of homes available.The number for sale across the country is down 33 percent compared to a year ago.Pittsburgh and Los Angeles saw the biggest jump in housing, with respectively a 25% and 24.3% jump in median listing price from this time a year ago.The average listing is on the market for 60 days, marking no change from this time a year ago. 550

HILLSBOROUGH, Calif. (KGTV) — Yabba, dabba, uh-oh.Neighbors of a San Francisco-area home known for its prehistoric theme are up in arms over the lengths in which its homeowner has gone to cement its look.Known in Hillsborough as "The Flintstone House" because of its similarity to the classic cartoon, has a "yabba dabba doo" sign in its front yard and its rounded, colorful facade looks like Fred and Wilma's homestead.RELATED: Escondido's Heartbreak Hotel clad in 50s-era memoribilia, statuesBut installations on the property have pushed things too far according to neighbors and city leaders, KPIX reports."I don't like the way she did the back yard, you know, when I pass by 280 and look at that, you know, this is Hillsborough, not amusement park," neighbor Kathy Park said. Large brown dinosaurs and statues of Flintstones characters have been added to the property over the last year, according to KPIX.RELATED: A taste of New Zealand moves into University Heights with Kairoa BrewingAttempts by the city to contact the homeowner, Florence Fang, have been unsuccessful."I sent her a letter back in January, which she ignored," Mark Hudak, assistant city attorney, said. "And therefore, we had to file a lawsuit because it was clear she was not going to remove any of this work."Fang has reportedly tried to now apply for permits, but the city wants everything removed to start with a fresh slate. 1411

Happening now LIVE! Celebration of the certification of the eradication of wild #polio in the @WHO African Region at #RC70AFRO.https://t.co/EJ5EgB44LV— WHO African Region (@WHOAFRO) August 25, 2020 205

GLENDALE, Ariz. (AP) — The Arizona Coyotes have renounced their rights to their top 2020 draft pick after learning more about his bullying of a Black classmate four years ago.The team parted ways with Mitchell Miller after taking heat for selecting him in the fourth round earlier this month despite knowing of his 2016 assault conviction.Arizona acknowledged it knew about the incident when it selected Miller.President and CEO Xavier Gutierrez said discovering more about it, and the effect it had on bullying victim Isaiah Meyer-Crothers and his family led to this decision."We have decided to renounce the rights to Mitchell Miller, effective immediately," said Gutierrez in a press release. "Prior to selecting Mitchell in the NHL Draft, we were aware that a bullying incident took place in 2016. We do not condone this type of behavior but embraced this as a teachable moment to work with Mitchell to make him accountable for his actions and provide him with an opportunity to be a leader in anti-bullying and anti-racism efforts. We have learned more about the entire matter, and more importantly, the impact it has had on Isaiah and the Meyer-Crothers family. What we learned does not align with the core values and vision for our organization and leads to our decision to renounce our draft rights. On behalf of the Arizona Coyotes ownership and our entire organization, I would like to apologize to Isaiah and the Meyer-Crothers family. We are building a model franchise on and off the ice and will do the right thing for Isaiah and the Meyer-Crothers family, our fans, and our partners. Mr. Miller is now a free agent and can pursue his dream of becoming an NHL player elsewhere.The news comes after an extensive exposè of Miller's bullying Meyer-Crothers, who has developmental disabilities, back in Ohio, was published on Oct. 26 by the Arizona Republic.According to the Toledo Blade, Miller and another student were found delinquent on counts of assault and violating the Ohio Safe Schools Act.In court, Miller admitted that he and Hunter McKie made Meyer-Crothers "eat a candy push pop after wiping it in a bathroom urinal," the Toledo Blade reported back in 2016.Sylvania Schools suspended Miller after the incident.Miller becomes an NHL free agent effective immediately.According to ESPN, North Dakota head coach Brad Berry told the Grand Forks Herald that Miller was still part of their program. 2422