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SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562

SAN DIEGO (KGTV) -- Two horses died Sunday after being seriously injured during separate races at the Del Mar Racetrack.A third horse was also hospitalized with an injury.The track tweeted at 2:17 p.m. confirming that in Sunday's third race, Ghost Street suffered a "catastrophic injury to his left front sesamoid and was humanely euthanized."Ghost Street was a 3-year-old gelding.A short while later, Prayer Warrior, a 3-year-old colt, was euthanized after suffering an injury to his front leg in Sunday's sixth race. 527

SAN DIEGO (KGTV) — Two weeks ago, the county warned San Diegans to continue practicing social distancing, washing of hands, and wearing facial coverings over the Labor Day weekend to thwart the spread of COVID-19.County public health officials had been clear that they did not want to see the same case spikes that followed July 4th and Memorial Day.Now that Labor Day has passed, local doctors say they have yet to see the same spike in coronavirus cases seen after holidays earlier this summer."We have not seen a sustained rate of 30, 40, 60 positives like we did around July 4. We're not seeing it yet," said Dr. David Pride, an infectious disease specialist at UC San Diego.Pride says the difference may be due to residents being more educated about the virus and how to best slow the spread. For the other two holidays, schools were also still closed.According to the county, 10 days after July 4 the region's positivity rate was 6.3%. Currently, the county's positivity rate is 4.4%."We're 10 days out, no big jump so far, our positivity rates suggest that something is different this time and hopefully that will continue for a week or two," Pride said.While San Diego County's positivity rate is low, it's the region's case rate (cases per 100,000 residents) that continues to be an issue. And now, it's the county's case rate that threatens to push the region's into a stricter reopening tier."This time around they're not sitting home, they're not socially distancing, so we're gonna see spikes that are largely unrelated to the Labor Day weekend," says Pride.And with more fall holidays approaching, Pride says residents will need to continue their vigilance through the holidays as spikes in cases are more likely. 1735

SAN DIEGO (KGTV) -- We've all seen the nasal swabs being pushed far up noses to test for coronavirus. And if you've had it done, you know it's uncomfortable. But more tests are being developed where all you have to do is spit into a tube."You basically open up your mouth, we collect a tiny bit of saliva and you're done. Your side is done," said Dr. Henry Ji, President and CEO of San Diego based Sorrento Theraputics.According to Ji, the biopharma company is on track to start producing a rapid saliva test developed by researchers at Columbia University.It's being called "COVI TRACE" and it can be used almost anywhere.It gives results in about 30 minutes, with the liquid color changing from red to yellow if it's positive for Covid-19.Preliminary results indicate the test has high accuracy rates.Sorrento also says "COVI TRACE" is highly sensitive, meaning it can detect the presence of Covid-19 very early on.Sorrento executives say they plan to submit the test for FDA approval within the next few weeks."While the FDA is reviewing and leading up to review we are gearing up to manufacture hundreds of thousands and millions of tests; eventually anticipating about a hundred million tests a month," said Sorrento's Henry Brunswick.As for the cost, Ji says they're trying to keep it widely affordable, at around .At this point there's no estimate for when the rapid saliva "COVI TRACE" test could be approved by the FDA, but Sorrento is submitting an emergency use request in hopes of speeding up the process. 1528

SAN DIEGO (KGTV)- A new effort is underway to revive a San Diego public golf course that's falling apart.  The "Friends of Presidio Hills Golf" went before the city council Tuesday urging them to take up the issue.  Their plan is to restore the course to its former glory days.Presidio Hills in Old Town is a local golf course with a storied past and an uncertain future."It needs to be completely redone," said John Vallas, who spearheaded the proposal.The place many once called the "cradle of golf" in San Diego is now a long shot from being up to par. 578

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