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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871

Judge Stephen Reinhardt, a liberal federal appeals court judge who was part of a panel that rejected California's Proposition 8 same-sex marriage ban as unconstitutional, died Thursday, according to a court spokesperson. He was 87.Reinhardt, who served on the US 9th Circuit Court of Appeals, died of a heart attack during a visit to his dermatologist, according to spokesman David Madden.One of the last remaining federal judges appointed by then-President Jimmy Carter, nearly four decades ago, Reinhardt emerged as a staunch critic of the Trump administration's deportation policies and travel ban in the final years of his life."We have lost a wonderful colleague and friend. As a judge, he was deeply principled, fiercely passionate about the law and fearless in his decisions," Chief Judge Sidney R. Thomas of the 9th Circuit said in a statement."He will be remembered as one of the giants of the federal bench. He had a great life that ended much too soon," Thomas said.Trump has slammed the court as being liberal and a symbol of "a broken and unfair" court system.Reinhardt's passing leaves a progressive vacancy on the court for Trump to potentially fill with a conservative vote.Reinhardt was born in New York in 1931. He earned a bachelor's degree from Pomona College in 1951 and a law degree from Yale Law School in 1954, according his biography. In 1979, former President Jimmy Carter appointed him to the appeals court, which is based in San Francisco.Reinhardt's big moment in history would come three decades after his appointment.In 2012, he was part of a three-judge panel that struck down California's voter-approved Proposition 8, arguing that the ban unconstitutionally singled out gays and lesbians for discrimination.In a split decision, the panel found that Proposition 8 "works a meaningful harm to gays and lesbians" by denying their right to civil marriage in violation of the 14th Amendment.Five years later, Reinhardt would become critical of the Trump administration.In March 2017, he had some pointed words for President Donald Trump in an opinion issued when the 9th Circuit refused to rehear the travel ban case."I am proud to be a part of this court and a judicial system that is independent and courageous," wrote Reinhardt, "and that vigorously protects the constitutional rights of all, regardless of the source of any efforts to weaken or diminish them."In May 2017, Reinhardt slammed the Trump administration's deportation policies. He said it was unfair for the government to kick out a 43-year-old coffee farmer who had built a life as a successful businessman in Hawaii. But the judge said he couldn't do anything to halt the deportation."President Trump has claimed that his immigration policies would target the 'bad hombres,'" Reinhardt wrote in an opinion published by the 9th Circuit Court of Appeals in May 2017. "The government's decision to remove Magana Ortiz shows that even the 'good hombres' are not safe."Condolences poured in Thursday from former law clerks."Judge Reinhardt was one of a kind -- a liberal (don't dare say "progressive"!) from another era, still championing justice and the rights of all as the country shifted around him," said Brian Goldman, a former law clerk. 3244

Joel Arrona was heading to a San Bernardino, California, hospital with his pregnant wife for a planned cesarean section when Immigration and Customs Enforcement officers detained him, forcing his pregnant wife to complete the journey and deliver the baby without him.Arrona, 35, is "a citizen of Mexico illegally residing in the United States" and has an outstanding warrant for homicide charges in Mexico, ICE said in a statement.His wife, Maria del Carmen Venegas, 32, says the charges are "a misunderstanding" in Mexico.His detention took place Wednesday, when Arrona was driving to the 10 a.m. appointment and decided to stop for gas. In an interview with CNN on Saturday, Venegas said people who "looked like security" knocked on her window. 754

KANSAS CITY, Mo. — Police arrested two 25-year-old men after a statue of President Andrew Jackson was vandalized Thursday afternoon outside the Jackson County Courthouse in downtown Kansas City, Missouri.A protest group gathered outside the courthouse earlier in the afternoon before the statue was spray-painted with obscenities as well as the phrase "slave owner."Kansas City Police Department (KCPD) officers were called to the courthouse shortly after 5:30 p.m. Thursday to investigate ongoing vandalism at the statue and observed two suspects spray painting the monument."Officers were able to identify the two individuals responsible from a distance," a KCPD spokesman said in a statement. "Once the crowd began to disperse and they were a safe distance away, the two suspects were taken into custody in front of Police HQ."Police also called a KC Parks and Recreation crew to deal with the graffiti. The workers covered the statue with a tarp shortly before 9 p.m.Unless officials can remove the graffiti, the statue will remain covered until the county legislature decide what to do with it. Jackson County Sheriff's Deputies will frequent the statue to prevent further damage.After the incident, the protest had moved to Ilus W. Davis Park near East 10th Street and Locust Avenue."Both suspects are being detained tonight for further investigation and determination of applicable charges," a KCPD spokesman said.Jackson — the seventh president of the U.S., who served from 1829 to 1837 — is among 12 former presidents who owned slaves before slavery was outlawed following the Civil War. Jackson became quite wealthy as a slave-owning plantation owner. His grave was defaced in 2018.Jackson County Executive Frank White Jr. released a statement shortly after the vandalism, which called for the statue's removal."Countless men, women and children come through the doors of our courthouses every day," White's statement read, in part. "And every day, racism and discrimination are staring them in the face. Statues of Andrew Jackson — our country's seventh president and county's namesake — stand outside two of our courthouses, public buildings where we want and need people to feel welcome. Yet, they are greeted by a man who owned hundreds of slaves, opposed the abolitionist movement and caused thousands of Native Americans to die when he forced them out of their homeland for white settlement. As long as these statues remain, our words about fairness, justice and equality will continue to ring hollow for many we serve."According to a release from White's office, he planned to "address the issue and recommend removal of the statues to the County Legislature" during the next meeting Monday morning.The Jackson County Prosecutor's Office agreed to pay for plaques on both statues that detail Jackson's historical role in disenfranchising non-white people after the county legislature voted to add the plaques in December 2019. Due to the COVID-19 pandemic, the plaques have not yet been added to the statues.White acknowledged that his stance on removing the statues might not be popular, but he believes it is necessary given the outpouring of cries for justice since a Minneapolis police officer drove a knee on George Floyd's neck as he laid facedown on the pavement until he died one month ago."In the month since George Floyd was tragically murdered, I have been inspired by the diversity of faces, voices, and ideas that have come forward and demanded we do better," White said. "What once could be described as a small minority pleading for change, has grown into a broad and diverse chorus of voices no longer pleading, but now demanding equality and making clear they will settle for nothing less. I am hopeful that we are seeing a true shift in the minds and hearts of people regardless of their age, race, gender or political affiliation. As we move forward, we must acknowledge the role that racism plays in our community and our responsibility to take action, which may sometimes be unpopular, to ensure everyone feels safe, feels welcome, and ultimately, is treated equally in Jackson County."White said he would ask the Jackson County Legislature to form a special committee Monday and begin public hearings to discuss removing the statues.He said Jackson County Prosecutor Jean Peters Baker, whose office agreed to pay for the plaques seven months ago, reached out recently to discuss removing the statues."I welcome the opportunity to work with the Legislature and fellow elected officials to find a better home for these statues where their history can be put into the appropriate context for us to learn from, but I am convinced that home is not in front of our courthouses," White said.He concluded his statement by writing, "Let me be clear — we can never erase history. It is already written. But we don't need symbols to remind us of the decades of oppression endured by people of color when that is the very thing we are desperately trying to dismantle and heal from today. Like all great counties, this is an opportunity for us to change and evolve together, for the better."This story was originally published by KSHB in Kansas City, Missouri. 5195

KANSAS CITY, Mo. (AP) — President Donald Trump said Friday that Congress should provide all the money he wants for his promised U.S.-Mexico border wall, and he called illegal immigration a "threat to the well-being of every American community."Trump spoke hours after signing a short-term spending bill that covers key government departments for two more weeks, until Dec. 21, setting up a pre-Christmas showdown over the wall.The president wants the next spending package to include at least billion for the proposed wall. House Democratic leader Nancy Pelosi of California rejected that a day earlier.At an appearance in Kansas City, Missouri, Trump accused Democrats of playing a political game, and said it was one that he ultimately would win."Congress must fully fund border security in the year-ending funding bill," Trump said as he helped close the 2018 Project Safe Neighborhoods law enforcement conference, which was sponsored by the Justice Department. "We have to get this done.""They're playing games," he said of Democrats. "They're playing political games. I actually think the politics of what they're doing is very bad for them. We're going to very soon find out. Maybe I'm not right. But usually I'm right."He also said money for a program that encourages federal, state and local authorities to collaborate on crime-fighting strategies was increased by million this year. The president said he will ask Congress for more money next year, but didn't say how much.Trump said his administration is giving law enforcement officials the resources they need to do their jobs. He said there are more than 200 new violent crime prosecutors nationwide and cities have access to 0 million worth of surplus military equipment.Introducing Trump was acting Attorney General Matthew Whitaker. Trump announced before leaving Washington that he planned to nominate William Barr, who was attorney general under President George H.W. Bush, to again lead the Justice Department.The short-term spending bill avoided a partisan fight that had been expected this week as Washington. It was put on hold for ceremonies honoring Bush, who died Nov. 30.Trump is set to meet Tuesday at the White House with Pelosi and Senate Democratic leader Chuck Schumer of New York. Republicans control the House and Senate now, but Democrats will retake the majority in the House in January after midterm election victories last month.The president said the money he is demanding from Congress would fully pay for Immigration and Customs Enforcement officers, attorneys, detention beds and the border wall, which he said is needed "more than ever."Trump has been agitated by multiple caravans of Central American migrants that have made their way to the U.S.-Mexico border. Several times he has threatened to seal off entry into the U.S. He claims many of the migrants are criminals or individuals unwanted in the U.S."Every American citizen is entitled to a safe community and a secure border," Trump said.___Associated Press writers Zeke Miller and Deb Riechmann in Washington contributed to this report. 3105