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WASHINGTON, June 7 (Xinhua) -- Advanced hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment, according to a new study published Tuesday in Gastroenterology, the official journal of the American Gastroenterological Association Institute.The study shows that patients who received peginterferon plus ribavirin treatment and who drank three or more cups of coffee per day were two times more likely to respond to treatment than non- drinkers.Among non-drinkers, 46 percent had an early virologic response; 26 percent had no detectable serum hepatitis C virus (HCV) ribonucleic acid at week 20; 22 percent had no detectable serum at week 48; and 11 percent had a sustained virologic response. In contrast, the corresponding proportions for those who drank three or more cups of coffee per day were 73 percent, 52 percent, 49 percent and 26 percent, respectively."Coffee intake has been associated with a lower level of liver enzymes, reduced progression of chronic liver disease and reduced incidence of liver cancer," said Neal Freedman, of the National Cancer Institute and lead author of this study. "Although we observed an independent association between coffee intake and virologic response to treatment, this association needs replication in other studies."Approximately 70 to 80 percent of individuals exposed to HCV become chronically infected. Worldwide, these individuals are estimated to number between 130 and 170 million. Higher coffee consumption has been associated with slower progression of pre- existing liver disease and lower risk of liver cancer. However, the relationship with response to anti-HCV treatment had not been previously evaluated.
WASHINGTON, June 21 (Xinhua) -- Brain cancer patients who are able to exercise live significantly longer than sedentary patients, U.S. scientists at the Duke Cancer Institute have reported.The finding, published online this week in the Journal of Clinical Oncology, adds to recent research that exercise improves how cancer patients feel during and after treatments, and may also extend their lives.The study enrolled 243 patients with advanced recurrent gliomas, lethal brain malignancies that typically result in a median life expectancy of less than six months. The patients who reported participating in regular, brisk exercise -- the equivalent of an energetic walk five days a week for 30 minutes -- had significantly prolonged survival, living a median 21.84 months versus 13.03 months for the most sedentary patients."This provides some initial evidence that we need to look at the effects of exercise interventions, not only to ease symptoms but also to impact progression and survival," said Lee Jones, associate professor in the Duke Cancer Institute and senior author of the study.
WASHINGTON, Aug. 4 (Xinhua) -- Researchers have found a way to turn mouse embryonic stem cells into sperm and this finding opens up new avenues for infertility research and treatment, according to a study published Thursday in the online edition of journal Cell,A Kyoto University team coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and shown that these cells can give rise to healthy sperm. The researchers say that such in vitro reconstitution of germ cell development represents one of the most fundamental challenges in biology.When transplanted into mice that were unable to produce sperm normally, the stem cell derived PGCs produced normal-looking sperm, which were then used to successfully fertilize eggs. These fertilized eggs, when transplanted into a recipient mother, produced healthy offspring that grew into fertile male and female adult mice. The same procedure could produce fertile offspring from induced pluripotent stem cells that are often derived from adult skin cells."Continued investigations aimed at in vitro reconstitution of germ cell development, including the induction of female primordial germ cell-like cells and their descendants, will be crucial for a more comprehensive understanding of germ cell biology in general, as well as for the advancement of reproductive technology and medicine," the researchers wrote.
People look at a W154 Mercedes Benz racing car at a vintage car show marking the German car maker's 125 anniversary at the former Tempelhof airport in Berlin, August 27, 2011.
BEIJING, May 30 (Xinhuanet) -- Chronic diseases, including heart disease, stroke, cancer, chronic respiratory diseases and diabetes, are the leading cause of mortality in China, representing 85 percent of all deaths, said a senior health official.Kong Lingzhi, deputy director of the disease prevention and control bureau under the Ministry of Health, made the remarks on Saturday at the Forum of Prevention and Control of Chronic Disease."China is facing a great challenge from chronic diseases, which has a serious impact on both the economy and society," said Kong.Each year, about 3.7 million people die before they reach 60 because of chronic diseases. There are currently 200 million hypertension patients and 90 million diabetics in China, official statistics show.To address the challenge, "the government is now drafting an inter-ministerial roadmap for chronic disease intervention, which will set targets, define responsibilities and distribute guidelines for the prevention and control of chronic diseases," she said.The initiative aims to strengthen national and global monitoring and surveillance; scale up the implementation of evidence-based measures to reduce risk factors, such as tobacco use, an unhealthy diet, physical inactivity and harmful alcohol use; and improve access to cost-effective healthcare to prevent complications, disabilities and premature death.But more importantly, the roadmap will help gain attention and support for preventing and controlling chronic diseases and place it high on government working agendas, Kong explained.The government has focused more on addressing instant health crises up to now and policy and funding support for chronic disease control and prevention was very limited, admitted Mao Qun'an, spokesman of the ministry.Given that chronic disease control requires a systematic approach, tasks such as public health education, training for medical workers (especially the grassroots ones) and policies encouraging doctors' involvement need to be carried out, he said.The ultimate goal is to prevent people from getting ill rather than treating diseases, he added.Lei Zhenglong, deputy director of the disease prevention and control bureau, said that to enhance the capacity of medical workers was now the top priority for the initiative.At present, effective disease prevention work usually contradicts the financial interests of clinical doctors, analysts said.A respiratory disease doctor surnamed He with the Peking University People's Hospital said that he came under pressure from the hospital authorities when the number of inpatients declined due to his efforts to inform his patients about chronic disease prevention.