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SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) - Many Asian American business owners continue to struggle during the pandemic, but a North County teen is hoping to help by creating a website to support local restaurants."I was hearing a lot of stories about Asians in my community experiencing discrimination during the pandemic," said 17-year-old Kaia Culotta.The teen said coming from a family of small business owners, she wanted to do something to help."I realized that there wasn't an easily accessible, comprehensible list of Asian owned businesses in my community," said Culotta. "So, I saw a need for that."For weeks, Culotta learned how to code through free programs online to build a website. The "Help Asian Owned Businesses" site has an extensive list of restaurants located around the county.Culotta said her project sparked the interest of San Diego City Councilmember Chris Cate. He even shared a video promoting the site on social media."It is awesome. It's such a neat thing to be doing out of the goodness of her heart," said Joe Kao, owner of R3fresh Juice Bar.After seeing Cate's video, the small business owner reached out to the teen to thank her for putting the site together.Kao said his business, like many others, had fewer customers during the pandemic. "We definitely saw a drop in business, but we've stayed open," he said.Kao applauds Culotta's work and thanks her for thinking of the county's small Asian business owners. 1430

SAN DIEGO (KGTV) — In a departure from recent years, Warner Bros. will be a no-show at San Diego Comic-Con's revered Hall H this year.A WB spokesperson confirmed to 10News that the studio and DC Comics will forgo any Hall H panel. In recent years, Warner Bros. has been pivitol for Hall H panels, especially in 2018 when Marvel and HBO elected not to take the stage.The decision was made all the more surprising — for fans, disappointing — considering the studio's upcoming slate of comic book movies, including "Joker" (Oct. 4, 2019), "Birds of Prey and the Fantabulous Emancipation of One Harley Quinn" (Feb. 7, 2020), "Wonder Woman 1984" (June 5, 2020), and "The Batman" (June 25, 2021).MORE COMIC-CON 2019 NEWSLast year, the studio used Hall H to preview "Wonder Woman 1984," "Aquaman," "Shazam!," "Fantastic Beasts: The Crimes of Grindelwald," "Godzilla: King of the Monsters," and "The Lego Movie 2: The Second Part.""Wonder Woman" director Patty Jenkins confirmed the news on Twitter this week, saying, "By now you’ve heard: WB isn’t going to Hall H this year. We’re so sad to miss you there! And waiting until Dec. to start our official #WW84 campaign in full-- But the truth is… we can just… barely… wait…" 1224

SAN DIEGO (KGTV) — It's a weekend packed with Oktoberfests across San Diego County as October and the fall season kicks into fear.El Cajon, La Mesa, Carlsbad, and Julian all celebrate Oktoberfest this weekend, with fun fall festivals featuring delicious brews, games, folk music and dancing, and German cuisine.If you're looking for some early scares, Balboa Park's Haunted Trail is open for the season. Head to the park if you dare for a hike like none other.SAN DIEGO HALLOWEEN:Frightful fun: San Diego Halloween, fall events for familiesExperience Halloween chills at these San Diego attractionsSpirited shindigs: Halloween parties for San Diego's 21+ crowdPacific Beach and Mira Mesa also welcome the community out this weekend for their own street fairs, with live music, arts and crafts, and more fun in the sun.THURSDAYOktoberfest in El CajonWhere: German American Societies of San Diego; Cost: - (Thursday - Sunday) Enjoy live German "Oom-Pah" music, traditional foods like bratwurst and ox-on-the-spit, German beers, folk games and dancing, and a kids' zone at El Cajon's massive Oktoberfest party.Haunted Trail at Balboa ParkWhere: Marston Point; Cost: - (Thursday - Sunday) Prepare for a scare as you walk down the mile-long trail. The theme for 2019 is “Stranger Things” and features the swampy fog of the upside down. Pregnant women and young children are banned from entry.FRIDAYFall Home Garden ShowWhere: Del Mar Fairgrounds; Cost: Free - (Friday - Sunday) Get all you need to spruce up your home and garden for fall at the Del Mar Fairgrounds this weekend for the annual Fall Home Garden Show. Guests can put together their own succulents, get tips from design and gardening experts, check out seasonal foliage, and more.La Mesa OktoberfestWhere: La Mesa Village; Cost: Free to attend(Friday - Sunday) La Mesa Village claims their Oktoberfest is the largest this side of the Mississippi. Head over for three-days of traditional sing-a-longs, original glücklich games like stein races and keg bowling, contests and crafts, and traditional German dishes and food.SATURDAYPacific BeachfestWhere: PB Boardwalk, from Felspar St. to Thomas St.; Cost: FreeHit the Pacific Beach boardwalk for a festival on the sand, with multiple stages of live music, arts and crafts village, kids zone, beer garden, fish taco contest, and more to check out. The day kicks off with a 5K and volleyball tournament and runs through to a beautiful beach sunset.Mira Mesa Street FairWhere: Camino Ruiz, from Mira Mesa Blvd. to New Salem St.; Cost: FreeEnjoy live music across two stages, international foods, kids activities and inflatables, and more at the Mira Mesa Street Fair this weekend. The US Marines will be on hand to give visitors a look at their explosive ordinance disposal robot and visitors can take a peek into a solar telescope. Carlsbad Oktoberfest and Family Fall FestivalWhere: Holiday Park; Cost: Free - Not only can you enjoy Oktoberfest in Carlsbad, but help support the local Rotary Club. The event hosts costume contests, arts and crafts, games and rides, live music, and delicious authentic German meals and brews.SUNDAYKSON's CountryFestWhere: Del Mar Fairgrounds; Cost: - Grab your favorite pair of boots and head down to Del Mar to see country music stars Billy Currington, Blanco Brown, Jon Langston and Dillon Carmichael perform. Line dancing will surely be in the mix along with fun games and delicious foods and drink.Rendezvous in PowayWhere: Old Poway Park; Cost: Varies(Saturday - Sunday) Living history groups help bring the 1800's alive in Poway, where the annual Rendezvous in Poway gives visitors the chance to pan for gold, experience western reenactments, peruse handcrafted arts, and learn more about the west's early history.Oktoberfest in JulianWhere: Julian Town Hall; Cost: Free to attend(Saturday - Sunday) Julian hosts a fun-filled Oktoberfest and fall celebration with live traditional folk and polka music, craft booths, raffles for prizes, and delicious German cuisine and Julian treats. 4062

SAN DIEGO (KGTV) -- It’s almost time to welcome back the nail-biting excitement of the Scripps National Spelling Bee.This year’s countywide bee will be held on March 15 at the McMillin Companies Event Center at Liberty Station.Roughly 100 spellers are expected to take the stage, making competition fierce.Last year was an exciting year for the competition as it saw its youngest speller ever, Edith Fuller of Oklahoma, who was only 5-years-old when she qualified.Fuller went all the way to the national stage. The spelling bee has been around for more than nine decades.The bee was founded in 1925 and has been held every year since, except during the World War II years of 1943, 1944 and 1945.In 2017, the competition celebrated its 90th National Spelling Bee.2017’s winning word was marocain, which is “a ribbed crepe fabric used in women's clothing.”The Scripps National Spelling Bee will begin May 29 and end on May 31.  943

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