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GENEVA, Aug. 12 (Xinhua) -- 18 people seeking treatment at hospitals in Somalia had been confirmed cholera positive through laboratory tests, the Geneva based World Health Organization (WHO) said on Friday.The 18 positive cases were detected out of 30 stool samples collected from patients seeking treatment at hospitals for acute watery diarrhea, a symptom that could result from cholera, WHO spokesperson Tarek Jasarevic told reporters.All confirmed cases, including residents of Mogadishu district and those among internally displaced persons (IDPs), were said to be tested positive for the Vibrio cholera serotype "inaba", which had been the predominant serotype in Somalia for the past three years."These results are an alarming reminder of the critical situation in Mogadishu and other parts of Southern, Central Somalia, (which are) still experiencing drought, population displacement and conflict," Jasarevic said.WHO has reported a dramatic increase of acute watery diarrhea cases in Somalia.In June and July alone, 1,633 acute watery diarrhea cases had been registered in Banadir Hospital, Mogadishu, representing 38 percent of all reported cases in 2011, and a sharp rise comparing with the same period last year.The United Nations public health arm said the situation was related to poor sanitation and limited access to safe water in numerous informal IDP settlements and a limited capacity of existing health partners to access those settlements and provide essential health services.In addition, the high number of malnourished children due to the ongoing famine increased the susceptibility to waterborne diseases.
WASHINGTON, July 15 (Xinhua) -- Researchers at Mount Sinai School of Medicine have found that grape seed polyphenols -- a natural antioxidant -- may help prevent the development or delay the progression of Alzheimer's disease.The research, led by Giulio Pasinetti, was published online Friday in the Journal of Alzheimer's Disease, which causes brain changes that gradually get worse.This is the first study to evaluate the ability of grape- derived polyphenols to prevent the generation of a specific form of amyloid (A) peptide, a substance in the brain long known to cause the neurotoxicity associated with Alzheimer's disease.In partnership with a team at the University of Minnesota, Pasinetti and collaborators administered grape seed polyphenolic extracts to mice genetically determined to develop memory deficits and A neurotoxins similar to those found in Alzheimer's disease. They found that the brain content of the A*56, a specific form of A previously implicated in the promotion of Alzheimer's disease memory loss, was substantially reduced after treatment.Previous studies suggest that increased consumption of grape- derived polyphenols, whose content, for example, is very high in red wine, may protect against cognitive decline in Alzheimer's. This new finding corroborates those theories."Since naturally occurring polyphenols are also generally commercially available as nutritional supplements and have negligible adverse events even after prolonged periods of treatment, this new finding holds significant promise as a preventive method or treatment, and is being tested in translational studies in Alzheimer's disease patients," said Pasinetti.In Alzheimer's disease, brain cells degenerate and die, causing a steady decline in memory and mental function.

LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).
BEIJING, July 26 (Xinhuanet) -- The breast cancer is more deadly to black women than to whites, a new study found.This finding was published online Monday on the "Journal of Clinical Oncology" in the United States.The study was done by the City of Hope, a Comprehensive Cancer Center in Duarte, California.The researchers collected data from more than 4,500 U.S. women in the 35-64 age group who were diagnosed with breast cancer.With the passing of more than eight years, the researchers found the black women have a three times death rate than white women, after taking obesity and other diseases into account."It’s been long known that breast cancer in African-American women is a far less common disease than in white women. But when it occurs, it seems to be more aggressive and harder to treat," said Dr. Lisa Carey of the University of North Carolina’s Lineberger Comprehensive Cancer Center.But why the situations varied by race, scientists are still exploring the answer.
VIENNA, Aug. 11 (Xinhua) -- Austrian researchers have developed a method of using fungi and produced enzymes to split Polyethylene Terephthalate (PET) material into their initial state, enabling the recovery of all individual components, said the Austrian Center of Industrial Biotechnology (ACIB) Thursday in a press release.Enzyme is a special protein that acts as biological catalyst, for example, bacteria and fungi in the nature can break down long chain molecules.Researchers from the Technical University of Graz, the Technical University of Vienna and the Agricultural University of Vienna jointly found that efficient enzymes are capable to break and split PET into small fragments.With different methods, the researchers forced the fungi to overproduce their precious "split-tools" after they are modified and improved by genetic engineering.Through the new method developed by the ACIB, it is now possible to decompose the PET polymer to its initial monomers with high product quality and from this to produce new high-quality materials again.This circuit avoids waste and thus saves resources and is friendly to the environment, said Geog Guebitz, head of the Research Department on Enzymes and Polymers in the ACIB.He further explained that the ACIB has established a partnership with some industrial enterprises to carry out application experiments. From the current splitting time of 24 hours, the researchers expect to shorten the whole process to "a few hours," he added.PET is a common plastic material in the polyester family, widely used in the textile industry. PET film is mainly used in electrical insulation materials, which can be also used for production of film, X-ray films and computer taps, even to produce plastic bottle and other blow molding products.
来源:资阳报