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The Colorado marijuana industry has now resulted in more than billion in revenue for the state, the Colorado Department of Revenue announced this week.Revenue from marijuana taxes, licenses and fees hit just over .02 billion, according to the department's latest monthly report. 296

The judge presiding over the historic Oklahoma opioid trial will deliver his ruling Monday afternoon -- a decision that could have sweeping implications as other states and communities try to hold pharmaceutical companies responsible for the opioid epidemic that has killed hundreds of thousands of Americans since 2000.The state has accused Johnson & Johnson and its subsidiary, Janssen Pharmaceuticals, of creating a public nuisance that cost the state billions of dollars and destroyed thousands of lives. Johnson & Johnson has denied any wrongdoing and said it has been made a "scapegoat."Cleveland County District Judge Thad Balkman will issue his decision at 3 p.m. (4 p.m. ET) in his courtroom in the college town of Norman.It is the first state trial attempting to hold a pharmaceutical company accountable for one of the worst epidemics in history. The state has asked for nearly .2 billion to fix the epidemic 943

The federal judge overseeing the case against Jeffrey Epstein on Wednesday ordered a hearing to discuss prosecutors' effort to dismiss the indictment against the alleged sex trafficker in the wake of his death.In a court filing, US District Court Judge Richard Berman said he believed the August 27 hearing would help shed light on the conclusion of the case against Epstein. The New York City medical examiner determined Epstein died by suicide while in jail on August 10."The court believes that where, as here, a defendant has died before any judgment has been entered against him, the public may still have an informational interest in the process by which the prosecutor seeks dismissal of an indictment," the judge wrote.Even prior to Epstein's death, the case had attracted intense public interest.The judge added that Epstein's alleged victims may speak at the hearing, along with their lawyers, prosecutors and Epstein's defense team.Prosecutors file motion to dismiss indictmentEpstein had been charged with one count of sex trafficking of minors and one count of conspiracy to engage in sex trafficking. Prosecutors accused him of operating a sex trafficking ring in which he both paid underage girls to have sex with him and paid some of them to recruit other victims.He had pleaded not guilty and was set to face trial next year.Prosecutors on Monday filed court papers to dismiss the indictment against Epstein, a routine step in a case in which the defendant has died. Prosecutors said in the court filing that they had "made efforts to contact all identified victims since learning of the death of the defendant and will similarly notify all known victims" of the order to dismiss the indictment.Prosecutors had said hours after Epstein died that their office would continue to pursue an investigation of any of his alleged accomplices, and they hinted at that effort Monday."As this Office has previously stated publicly, it remains committed to doing its utmost to stand up for the victims who have already come forward, as well as for the many others who have yet to do so," prosecutors wrote. 2124

The 76th Golden Globe Awards took place Sunday night.The full list of film and television nominees follows with winners indicated in bold with an asterisk.MoviesBest Motion Picture - Drama"Black Panther""BlackKklansman""Bohemian Rhapsody" *WINNER"If Beale Street Could Talk""A Star Is Born"Best Motion Picture - Musical or Comedy"Crazy Rich Asians""The Favourite""Green Book" *WINNER"Mary Poppins Returns""Vice"Best Performance by an Actress in a Motion Picture - DramaGlenn Close ("The Wife") *WINNERLady Gaga ("A Star Is Born")Nicole Kidman ("Destroyer")Melissa McCarthy ("Can You Ever Forgive Me?")Rosamund Pike ("A Private War")Best Performance by an Actor in a Motion Picture - DramaBradley Cooper ("A Star Is Born")Willem Dafoe ("At Eternity's Gate")Lucas Hedges ("Boy Erased")Rami Malek ("Bohemian Rhapsody") *WINNERJohn David Washington ("BlackKklansman")Best Performance by an Actress in a Motion Picture - Musical or ComedyEmily Blunt ("Mary Poppins Returns")Olivia Colman ("The Favourite") *WINNERElsie Fisher ("Eighth Grade")Charlize Theron ("Tully")Constance Wu ("Crazy Rich Asians")Best DirectorBradley Cooper ("A Star Is Born")Alfonso Cuaron ("Roma") *WINNERPeter Farrelly ("Green Book")Spike Lee ("BlackKklansman")Adam McKay ("Vice")Best Performance by an Actor in a Motion Picture - Musical or ComedyChristian Bale ("Vice") *WINNERLin-Manuel Miranda ("Mary Poppins Returns")Vigo Mortensen ("Green Book")Robert Redford ("The Old Man and the Gun")John C. Reilly ("Stan and Ollie")Best Supporting Actress in a Motion PictureAmy Adams ("Vice")Claire Foy ("First Man")Regina King ("If Beale Street Could Talk") *WINNEREmma Stone ("The Favourite")Rachel Weisz ("The Favourite")Best Supporting Actor in a Motion PictureMahershala Ali ("Green Book") *WINNERTimothee Chalamet ("Beautiful Boy")Adam Driver ("BlackKklansman")Richard E. Grant ("Can You Ever Forgive Me?")Sam Rockwell ("Vice")Best Original Score in a Motion PictureMarco Beltrami ("A Quiet Place")Alexandre Desplat ("Isle of Dogs")Ludwig G?ransson ("Black Panther")Justin Hurwitz ("First Man") *WINNERMarc Shaiman ("Mary Poppins Returns")Best Original Song in a Motion Picture"All the Stars" ("Black Panther") 2192

The creator of the Labradoodle cross-breed has said he inadvertently unleashed a "Frankenstein('s) monster."Wally Conron, 90, who worked for Guide Dogs Victoria in Australia when he bred the first Labrador-Poodle cross in 1989, spoke of his regrets at having begun a trend for designer breeds on an ABC podcast."I opened a Pandora's box and released a Frankenstein('s) monster," he said.His "big regret" is that his invention paved the way for "unethical, ruthless people" to breed the dogs without thinking of the health of their offspring.According to Conron, the majority of Labradoodles are "either crazy or have a hereditary problem," with healthy examples of the breed "few and far between."He believes that people have now gone too far with cross-breeding, which can increase a dog's risk of congenital disease, particularly down the generations. On the podcast, he laid particular scorn on the new Rottweiler-Poodle hybrid, known as a Rottle or a Rottie-Poo.Conron's original purpose in crossing a Labrador with a standard Poodle (which has a non-shedding coat) had been to provide a guide dog for a blind woman in Hawaii whose husband was allergic to dogs.The resulting litter of three was small, but one of the puppies did not trigger the husband's allergies and was sent to Hawaii to be her guide dog.As no one wanted the two remaining puppies, Conron asked the PR department at his work to spread the message of this new breed. Labradoodles quickly became popular in Australia and further afield.Now, designer breeds have become widespread -- but so has criticism of the consequences. Labradoodles, for example, can develop health problems common to Labrador Retrievers and Poodles such as hip dysplasia and eye disease.Colin Tennant, a British expert on dog behaviour with 45 years of experience in the industry, told CNN: "In essence, you are blindly breeding and altering genetics of the line without foreknowledge."Although Tennant said he doesn't have a problem with cross-breeding in general, he noted that breeders should pay more attention to dog's health.One example, he said, was the Bichon Frise, whose eyes water. "It must be in agony all the time," he explained. "They breed the face flat so they look humanoid because we find that attractive, with no consideration for the permutations we are producing with regards the dog's welfare or health." 2383