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Pfizer announced Monday that its COVID-19 vaccine candidate has been 90% effective.In a press release, the company said that in Phase 3 trials, the vaccine has proven to promote a vaccine efficacy rate above 90% following the two-shot regimen.The Associated Press said that while Pfizer's announcement means the company is on track to file an application for emergency use authorization later this month, it does not mean a vaccine is "imminent" and more studies are needed.Pfizer's vaccine candidate began Phase 3 testing in the summer and is among a handful of vaccine candidates that could be distributed in the coming months pending FDA approval.Phase 3 trials consist of testing about 30,000 voluntary participants in a double-blind study — meaning half of those participating receive the vaccine, and half receive a placebo. Pfizer's vaccine requires two shots, which need to be taken 28 days apart.According to Pfizer, 90% of those who were tested for the vaccine had developed protection against the virus seven days following the second shot.Pfizer is already in the process of producing millions of doses of its vaccine candidate after the U.S. government agreed to pay .95 billion for 100 million doses of the vaccine, should it prove effective. If and when the FDA grants approval for the vaccine, it will be distributed to hospitals around the country by the U.S. military in an effort the Trump administration has dubbed "Operation Warp Speed.Even though hundreds of thousands of doses of the Pfizer vaccine will be ready for shipment if it is approved for emergency use, it will need to be rationed in the first months of its availability. According to a playbook for "Operation Warp Speed," essential health care workers and people in high-risk populations would have the first opportunity to get a COVID-19 vaccine. The rest of the general public will be able to get the vaccine as more doses become available later in 2021.Pfizer was one of a handful of companies that pledged in September not to distribute their vaccine under political pressure, and would only do so if it proved to be effective in large scale trials.Monday's announcement sent stock market futures through the roof, as investors eyed a return to economic normalcy should Pfizer's vaccine be given emergency approval in the coming days or weeks.President Donald Trump also celebrated the announcement in a tweet on Monday morning."STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!" Trump tweeted. 2524

Police are investigating an alleged sexual misconduct incident at Las Brisas Academy in Goodyear, Arizona.The allegations were first reported to the principal Wednesday night, by the parent of the victim, who found text message conversations between 27-year-old Brittany Zamora and her 13-year-old male student.The conversation indicated there were sexual activities happening between the two, on and and off campus. According to police records, the teen's parents were alerted to the explicit messages by a parental app.After initially reporting the relationship to the Las Brisas principal, the 13-year-old's father also contacted Buckeye police.In a report made to police, the victim's father said he received a phone call from Zamora and her husband, who were allegedly "pleading with him not to contact the police." During the call, Zamora's husband reportedly asked to "meet up" and "settle this." 921

PARADISE, Calif. (AP) — More than a dozen coroner search and recovery teams looked for human remains from a Northern California wildfire that killed at least 48 -- making it the deadliest in state history -- as anxious relatives visited shelters and called police hoping to find loved ones alive.Lisa Jordan drove 600 miles (1,000 kilometers) from Yakima, Washington, to search for her uncle, Nick Clark, and his wife, Anne Clark, of Paradise, California. Anne Clark suffers from multiple sclerosis and is unable to walk. No one knows if they were able to evacuate, or even if their house still exists, she said."I'm staying hopeful," she said. "Until the final word comes, you keep fighting against it."Authorities updated the confirmed fatality number Tuesday night -- a figure that is almost certain to spike following the blaze that last week destroyed Paradise, a town of 27,000 about 180 miles (290 kilometers) northeast of San Francisco.RELATED: Interactive Fire maps: Camp Fire, Woolsey/Hill FiresAuthorities were bringing in two mobile morgue units and requesting 150 search and rescue personnel. Officials were unsure of the exact number of missing."I want to recover as many remains as we possibly can, as soon as we can. Because I know the toll it takes on loved ones," Honea said.Chaplains accompanied some coroner search teams that visited dozens of addresses belonging to people reported missing. For those on the grim search, no cars in the driveway is good, one car a little more ominous and multiple burned-out vehicles equals a call for extra vigilance.State officials said the cause of the inferno was under investigation.Meanwhile, a landowner near where the blaze began, Betsy Ann Cowley, said she got an email from Pacific Gas & Electric Co. the day before the fire last week telling her that crews needed to come onto her property because the utility's power lines were causing sparks. PG&E had no comment on the email.Stan Craig's sister, Beverly Craig Powers, has not returned numerous texts and calls, and the adult children of her partner, Robert Duvall, have not heard from their father, he said. The couple was last seen evacuating their Paradise home on Thursday with two pickup trucks and a travel trailer, so they could be camping.He knows friends and family are still being reunited with missing loved ones, but he said his unease grows every day. Still, the Fresno, California, resident wasn't planning on heading to the fire area. As a former firefighter himself, he said he understands the chaos wildfires cause."I'm going to stay here until I have something more to go on," he said.The blaze was part of an outbreak of wildfires on both ends of the state. Together, they were blamed for 50 deaths, including two in celebrity-studded Malibu in Southern California , where firefighters appeared to be gaining ground against a roughly 143-square-mile (370-square-kilometer) blaze that destroyed at least 370 structures, with hundreds more feared lost.All told, more than 8,000 firefighters statewide were battling wildfires that destroyed more than 7,000 structures and scorched more than 325 square miles (840 square kilometers), the flames feeding on dry brush and driven by blowtorch winds.There were tiny signs of some sense of order returning to Paradise and anonymous gestures meant to rally the spirits of firefighters who have worked in a burned-over wasteland for days.Large American flags stuck into the ground lined both sides of the road at the town limits, and temporary stop signs appeared overnight at major intersections. Downed power lines that had blocked roads were cut away, and crews took down burned trees with chain saws.The 48 dead in Northern California surpassed the deadliest single fire on record, a 1933 blaze in Griffith Park in Los Angeles. A series of wildfires in Northern California's wine country last fall killed 44 people and destroyed more than 5,000 homes.___Contributing to this report were Associated Press writers Sudhin Thanawala, Janie Har, Jocelyn Gecker and Daisy Nguyen in San Francisco and Andrew Selsky in Salem, Oregon. 4140

PHOENIX — A high school play with controversial costumes has some parents outraged.Three students at the Arizona State University Preparatory Academy Phoenix campus dressed in Ku Klux Klan costumes for a school play. Parents say the school never notified them or the rest of the student body that was not in the drama class.The popular play, "The Foreigner," was performed at an assembly for all high school students. "Three students dressed as the KKK walked down the middle of the assembly as part of a play," explained one parent, who wanted to remain anonymous at his daughter's request. "They were in hooded robes."The Klansmen are part of the scripted comedy play but this parent says the characters could have easily been portrayed without "full regalia.""We can talk about racial prejudice, we can talk about the insensitivity, but to have our children put on the robes and assume the characters, it's wrong...There is no justification for it," the parent said.A spokesperson for ASU Preparatory Academy issued the following statement: 1066

OZAUKEE COUNTY, Wis. (WTMJ) -- A Wisconsin woman has been charged with second degree recklessly endangering safety after she allegedly had her 9-year-old son ride on top of her minivan to hold down a plastic pool.According to the criminal complaint, it happened around 3 p.m. local time on Sept. 9, when officers responded to reports of a child riding on top of a minivan.A 911 caller followed Amber Schmunk, 28, of Fredonia, until she pulled over and took her child and the pool off the vehicle's roof. Schmunk then continued driving down the road and stopped at her sister’s house where police caught up with her.Schmunk told police picked up the pool at a residence but did not have enough room inside the minivan. She said she “decided to put the pool on top of the minivan, but had no way to strap it down, so she had her child climb on the roof and hold it down while she drove.”Schmunk admitted to police she had her oldest son ride on top of the minivan, “but only for a short time, maybe 20-30 seconds.” Schmunk later stated it was safe because she used a strap to tie the child down on top of the pool.She also told the officer that she believed it was “ok” as her father let her do things like that when she was that age.Schmunk will be back in court on Nov. 14. If convicted, she faces up to ten years in prison and up to a ,000 fine. 1417

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