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The US Treasury Department is sanctioning Turkey's ministers of justice and interior in response to the detention of American pastor Andrew Brunson, White House press secretary Sarah Sanders said Wednesday."We've seen no evidence that Pastor Brunson has done anything wrong," Sanders said, calling Brunson's detention "unfair and unjust."The two ministers will have any assets and properties under US jurisdiction blocked and US persons will be prohibited from engaging in financial transactions with the ministers. 523

The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722

The U.S. will finish the month of November with more than 4 million confirmed cases of COVID-19, by far the most it has recorded in any month since the beginning of the pandemic.According to a database kept by Johns Hopkins University, the U.S. recorded 4.3 million new cases of COVID-19 throughout the month of November. That represents more than 30% of the 13.3 million cases recorded throughout the country since the virus reached the U.S. in February.Throughout November, the U.S. set 10 daily records for newly-reported COVID-19 cases. The peak came on Friday, when Johns Hopkins says the U.S. saw more than 205,000 new cases — though those numbers may have been skewed by the Thanksgiving holiday when some local governments chose not to report new info.The mountainous increase in cases has resulted in a frightening increase in hospitalizations and hospital resource use. According to the COVID Tracking Project, a record 93,000 Americans across the country were hospitalized with COVID-19 as of Monday morning, an all-time record. On Oct. 31, that figure stood at just over 47,000. While hospitalizations have spiked across the country, 66% of those hospitalized are in the Midwest and South, meaning many rural hospitals in those regions are at capacity. With hospitals full, doctors and nurses are struggling to treat patients who are suffering from other emergency ailments.Sadly, the number of deaths from COVID-19 has steadily increased throughout the month. As of Monday morning, an average of 1,436 Americans had died of COVID-19 each day for the last week. On Oct. 31, that figure sat at just over 800. Therapeutics and new treatments for the virus have caused the death rate to fall since the springtime when nearly 2,500 Americans were dying every day. But despite the improvements in treatments, the U.S. continues to lose about as many Americans every two days that were lost in the Sept. 11, 2001 terror attacks.And while several companies have reported encouraging news regarding potential vaccines in recent weeks, health experts warn the pandemic will get much worse before they are widely available.Prior to Thanksgiving, Dr. Anthony Fauci — America's top infectious disease expert — warned that the holiday could cause the rate of transmission to rise exponentially, given that some celebrations included large indoor gatherings."The chances are that you will see a surge superimposed on a surge," Fauci said. 2450

The Trump administration's executive order threatening to withhold funding from sanctuary cities is unconstitutional, a US appeals court said Wednesday.This story is developing. 190

The U.S. women’s national team wants the U.S. Soccer Federation to repeal the anthem policy it instituted after Megan Rapinoe started kneeling during the “The Star-Spangled Banner.”The U.S. women’s team also wants the federation to state publicly that the policy was wrong and issue an apology to the team’s black players and supporters.“Further, we believe the Federation should lay out its plans on how it will now support the message and movement that it tried to silence four years ago,” the U.S. women’s team said in a statement posted on the Twitter feed of its players association Monday night.Rapinoe took a knee during the anthem at a pair of national team matches in 2016. She said she wanted to express solidarity with San Francisco 49ers quarterback Colin Kaepernick, who silently took a knee during the national anthem before NFL games to raise awareness of police brutality and racial injustice.The U.S. Soccer Federation then approved a policy in February 2017 that stated players “shall stand respectfully” during national anthems. The policy remains in place, though the unions for the men’s and women’s teams believe it doesn’t apply to their players because of their collective bargaining agreements.Kaepernick and Rapinoe each faced sharp criticism for the protest for years. But public sentiment has changed since George Floyd’s death last month.Floyd, a black man, died after a white Minneapolis police officer pressed his knee into Floyd’s neck while Floyd was handcuffed and saying that he couldn’t breathe. His death sparked protests in Minneapolis and around the country, some of which became violent.A lawyer for the men’s team union also called for the repeal of the policy and an apology in a statement provided to BuzzFeed News, which was the first to report on the U.S. women’s statement.A message was left by the AP seeking comment from the federation.___More AP soccer: https://apnews.com/Soccer and https://twitter.com/AP_Sports 1970