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SAN DIEGO (KGTV) – A suspicious backpack prompted a bomb squad response downtown Tuesday afternoon. According to San Diego Fire-Rescue, the incident unfolded around 3:30 p.m. just outside the federal building on the 800 block of Front Street. Authorities say a security guard at the building saw a man acting suspiciously before tossing a military backpack into a planter. After using special equipment to examine the bag, the bomb squad found only personal items inside the bag. The FBI said it sent agents to the scene, but that the "matter is being led by Federal Protective Services." 596

SAN DIEGO (KGTV) - After moving to San Diego almost three years ago, Derek and Terri Ruff are on a mission to experience everything the city has to offer. “Yes we are, it’s fantastic! We hardly leave the county, there’s just so much to do," said Derek.The couple moved here from New Mexico, and for nine years Derek's colon cancer seemed to be behind them. “I won’t say cancer-free, but I didn’t have any symptoms for years, until last May, whenever I came in for a checkup, and they discovered cancer again," said Derek.It was stage IV metastatic colon cancer.“It’s a lot. It’s a tough diagnosis, it’s really difficult to live through.”After three months of aggressive chemotherapy, Ruff's condition only got worse. His journey brought him to UC San Diego Health's Moores Cancer for a clinical trial, which unfortunately did not work. But he Ruff became a candidate for another trial involving natural killer cells created from stem cells.“These are patients who don’t have a lot of good options in terms of chemotherapy or immunotherapy," said Dr. Sandip Patel, a medical oncologist who is leading the trial at UCSD. Decades of research on natural killer cells have culminated in the new cancer treatment being developed by San Diego-based Fate Therapeutics.Fate is the first to mass produce cancer-killing cells from a type of stem cell called a human-induced pluripotent stem cell (iPSC). "The concept of utilizing the stem cells that are within us, within our blood factory, within our blood marrow, to create a master bank of cells that we can utilize to program in different ways to fight cancer with cellular immunotherapy."The off-the-shelf, iPSC-derived natural killer cell cancer immunotherapy received U.S. Food and Drug Administration approval to move into clinical trials in November 2018. Ruff is the first person in the world to receive the treatment and got his first dose in February.“Being the first is exciting but it was less so hearing that you have stage iv cancer and you don’t have much of a future, and now I feel hopeful, again," said Ruff.While it's too early to tell if the treatment is working, researchers are hopeful this treatment will one day help many cancer patients. 2212

SAN DIEGO (KGTV) — An unexplained odor was detected late Friday by several San Diego residents, from Point Loma to San Marcos.The National Weather Service San Diego tweeted they were unsure what was causing the "funky smell around San Diego," after residents began reporting the odor.They added that they could also smell it at their Rancho Bernardo offices. 366

SAN DIEGO (KGTV) - A San Diego resident is one of three patients across California infected with salmonella linked to an herbal supplement.The 44-year-old resident is the latest patient in the multi-state outbreak, according to the San Diego County Health and Human Service Agency.The supplement, kratom, is used as a stimulant and opioid substitute. It's also known as thang, kakuam, thom, ketom, biak, and Mitragyna speciosa, according to county health officials.RELATED: 28 sick in salmonella outbreak linked to kratom, CDC saysThe San Diego patient fell ill in January but has since recovered. They were not hospitalized, officials said.The Centers for Disease Control and Prevention has identified at least 40 cases of salmonellosis in 27 states. Fourteen patients have been hospitalized. The CDC has identified kratom products as the likely source, though a specific brand or supplier has yet to be named.CDC officials recommend people do not consume kratom in any form.RELATED: If it's not the flu, you might be sick because of this virusKratom is an herb that is currently legal in most parts of California and the U.S. The FDA issued a ban on imports of the herb in 2014.In 2016, the City of San Diego also passed a ban on the sale, possession, and distribution of mitragynine and hydroxyl-mitragynine, which are active components in kratom. Since 2014, there have been 10 deaths in the county associated with mitragynine.Salmonellosis is a common intestinal infection traditionally associated with undercooked poultry or eggs, contaminated water, or unpasteurized dairy products. Most who fall ill from it are sick for four to seven days and experience diarrhea, fever, vomiting, and abdominal cramps. 1759

SAN DIEGO (KGTV) - An early morning collision involving a tractor-trailer stopped traffic near Mission Valley Saturday.The big rig crash on northbound Interstate 15 near the I-8 connector blocked all lanes, creating a complete standstill of the morning commute.Traffic was being diverted onto I-8, however, all lanes reopened just before 6 a.m. It's not clear how the collision occurred.TRAFFIC MAP: FIND A NEW ROUTEIt's not clear if anyone was seriously injured in the crash.10News is monitoring this breaking news story. 530