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The Scripps National Spelling Bee is welcoming applicants for its second year of RSVBee, the invitational program that creates more opportunities for champion spellers to compete in the national finals in National Harbor, Maryland.Last year, more than 230 students competed in the national finals through RSVBee, including the 2018 Champion, Karthik Nemmani, from McKinney, Texas.To be eligible, students must attend a school that is enrolled in the Scripps National Spelling Bee program and be a school or community spelling champion during the 2018-19 school year. Students who previously competed in the national finals also are eligible to apply. Parents can complete the online application form on behalf of their children between now and March 22, 2019.There are new application and invitation acceptance guidelines for RSVBee: 841

The Southeastern Conference is considering barring league championship events in Mississippi unless the state changes its Confederate-based flag.“It is past time for change to be made to the flag of the State of Mississippi,” Commissioner Greg Sankey said in a statement Thursday. “Our students deserve an opportunity to learn and compete in environments that are inclusive and welcoming to all. In the event there is no change, there will be consideration of precluding Southeastern Conference championship events from being conducted in the State of Mississippi until the flag is changed.”The NCAA has already said it would not schedule postseason events in Mississippi because of the state flag.National protests about racial injustice have renewed debate about Confederate symbols. Mississippi has the last state flag that includes the battle emblem: a red field topped by a blue X with 13 white stars. White supremacists put the symbol on the flag in 1894 during the backlash to black political power that developed during Reconstruction.During a Black Lives Matter protest June 5 outside the Mississippi Governor’s Mansion in downtown Jackson, thousands of people cheered as an 18-year-old organizer, Maisie Brown, called for the removal of all Confederate symbols in the state, including from the flag.Bipartisan coalitions of state lawmakers have been trying to build momentum to change the flag, but Republican Gov. Tate Reeves has said repeatedly that if the banner is to be redesigned, it should be done by the state’s voters.People who voted in a 2001 election chose to keep the flag rather that replace it with a design that did not include the Confederate emblem.All of Mississippi’s public universities and several cities and counties have stopped flying the state flag in recent years because of the emblem. The state has two SEC schools — the University of Mississippi and Mississippi State University.Leaders at both universities said Thursday that the state should change the flag.“Mississippi needs a flag that represents the qualities about our state that unite us, not those that still divide us,” Ole Miss Chancellor Glenn Boyce and athletic director Keith Carter said in a joint statement. “We support the SEC’s position for changing the Mississippi state flag to an image that is more welcoming and inclusive for all people.”Mississippi State President Mark E. Keenum said in a statement that he respects Sankey’s position. Keenum said he wrote to state elected officials June 12 telling them that the university’s students, faculty and administrators have been on record in favor of changing the flag since 2015.“The letter said, in part, that our flag should be unifying, not a symbol that divides us,” Keenum said. “I emphasized that it is time for a renewed, respectful debate on this issue.” 2829

The sister of Charleston church shooter Dylann Roof was arrested Wednesday on charges of bringing weapons and drugs to her South Carolina high school, authorities said.Morgan Roof, 18, was arrested after a school resource officer at the A.C. Flora High School in Columbia, South Carolina was notified that Roof was carrying marijuana, pepper spray and a knife on campus, the Richland County Sheriff's Department said.Roof had also made an alarming Snapchat post expressing anger about the National School Walkout, The Post and Courier reported. A 17-minute walkout was staged at schools around the country on Wednesday to honor the 17 people killed at Florida's Marjory Stoneman Douglas High School last month and call for stricter gun control laws.No A.C. Flora High students were harmed Wednesday, authorities said.Roof was charged with simple possession of marijuana and two counts of carrying weapons on school grounds. A judge set a ,000 bond for Roof under the condition that she would not return to the school, CNN affiliate WIS reported.It's unclear whether she has an attorney.In a letter to parents, the high school principal addressed multiple incidents that took place Tuesday and Wednesday on campus, including the one involving Roof."I realize that rumors and the tragic school shootings in Florida are events that can cause anxiety for our students, parents, faculty, and the community," Principal Susan Childs wrote. "Be assured that the safety of our students will always be our top priority. We must continue to work together to maintain a safe and positive learning environment."South Carolina Governor Henry McMaster said "potential tragedy was avoided" Wednesday thanks to the students and educators who reported "suspicious activity" to a school resource officer."We owe a debt of gratitude to all involved who acted so quickly and decisively," McMaster said in a statement."For months, I have called on the General Assembly to join me in placing a trained, certified police officer in every school, in every county, all day, every day," the governor added.Roof's brother, Dylann, was formally sentenced to death last year for killing nine people at a historically black church in Charleston, South Carolina in 2015.The-CNN-Wire 2260

The U.S. regulators who will decide the fate of COVID-19 vaccines are taking an unusual step: Asking outside scientists if their standards are high enough.The Food and Drug Administration may have to decide by year’s end whether to allow use of the first vaccines against the virus. Thursday, a federal advisory committee pulls back the curtain on that decision process, debating whether the guidelines FDA has set for vaccine developers are rigorous enough.“We will not cut corners, and we will only use science and data to make that determination,” FDA Commissioner Stephen Hahn pledged at a meeting of the Milken Institute Wednesday.Exactly how much data his agency needs to be sure a vaccine is safe and effective is a key question for the advisers. An even bigger one: If the FDA allows emergency use of a vaccine before final testing is finished, will that destroy chances of ever learning just how well that shot -- and maybe competitors still being studied -- really work?“We can’t lose sight of the fact that it is in our societal interest to see these trials to completion,” said Dr. Luciana Borio, a former FDA acting chief scientist who will be watching the advisers’ debate.Plus, multiple vaccines are being studied -- shots made with different technologies that each have pros and cons.“The first vaccine is not necessarily the best vaccine,” cautioned Dr. M. Miles Braun, a former FDA scientist now with Georgetown University School of Medicine. If the trials aren’t allowed to finish, it may be difficult or impossible to ever know for sure.It’s a critical moment in FDA’s 114-year history. The government has spent billions to race a vaccine through a research process that usually takes years, and FDA faces unprecedented pressure from the Trump administration, fueling public skepticism that politics could overrule science.Interest is so high, FDA is airing the meeting on YouTube. Here are some key issues the committee will discuss:HOW MUCH EVIDENCE IS NEEDED?FDA is requiring manufacturers to do studies of at least 30,000 people to prove if a vaccine protects and how safe it is. Those studies must include adequate numbers of people at highest risk from COVID-19 -- older adults, minorities and anyone with underlying health problems.FDA has made clear that any vaccine must be at least 50% effective. And while the studies are designed to run for two years, companies may get enough evidence the shots are protective -- in at least some people -- to stop the trials early and seek what’s called an “emergency use authorization” for wider vaccinations.Despite White House objections, the FDA told vaccine makers earlier this month not to seek that speedier review until they’ve tracked at least half their trial participants for two months. With other vaccines, that’s about the amount of time when major side effects crop up.That’s not long enough, said the head of the non-profit ECRI Institute, which reviews medical technology for hospitals and insurers. In comments submitted to the advisory committee, ECRI’s Dr. Marcus Schabacker said FDA should require six months of follow-up.“Doing any less would simply risk too much, and the consequences may be severe,” he wrote. “A weak vaccine that loses public trust could poison the well for epidemic control for many years.”WOULD EMERGENCY USE DERAIL FULL ANSWERS ABOUT VACCINES?Normally when a study ends because of evidence that a vaccine is working, the participants who got dummy shots are offered the real thing.But if FDA allows emergency use of a COVID-19 vaccine, that’s not the same as having full proof the shot works, Borio cautioned.And if the participants in the placebo group are immediately offered the real shot, researchers may not be able to get answers about all the high-risk groups in the study — or tell how long the vaccine’s protection lasts, a process expected to take many more months.But Pfizer Inc., which with Germany’s BioNTech is developing one of the leading candidates, told FDA that if it’s granted emergency use authorization, it “would have an ethical obligation” to alert study participants who got a placebo and allow them vaccine access. The company wants FDA to look into “other scientifically and statistically sound methods” to determine long-term safety and effectiveness.Pfizer’s stance is likely to face pushback. The Infectious Diseases Society of America states that FDA’s panelists “should insist” that vaccine developers “present a compelling case” for how they will complete their trials if FDA grants early authorization of their vaccine.Clearing a vaccine based on premature or faulty data “could cause more harm” by “further eroding public confidence in all vaccines,” the group said.It’s an unprecedented dilemma. The FDA has previously allowed emergency use of only one vaccine, a decades-old shot that in 2005 was authorized to prevent anthrax poisoning.This time around, multiple COVID-19 vaccines are in the pipeline. Pfizer competitor Johnson & Johnson cautioned that early FDA clearance of one vaccine could “jeopardize integrity” of other ongoing trials if patients decide to drop out to seek the first cleared shot instead.The company asked regulators to explain what options are available to ensure completion of all ongoing COVID-19 vaccine trials.WHAT ABOUT LONG-TERM SAFETY MONITORING?Even a study of 30,000 people cannot spot a side effect that only strikes 1 in 100,000. So the government is planning extra scrutiny of every COVID-19 vaccine to hit the market.At first there will be limited doses given to just certain high-risk people -- and those early recipients are to get text messages daily for the first week after vaccination, and then weekly out to six weeks, asking how they’re feeling.FDA also will be checking databases of electronic health records and insurance claims, looking for any red flags.“There’s a kind of tracking that has to take place here on a massive basis that hasn’t taken place before,” said Dr. Jesse Goodman of Georgetown University, a former director of the FDA’s vaccine and biologics center.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 6274

The University Hospitals Fertility Clinic in Cleveland is facing dozens of legal actions after the failure in early March of a cryopreservation tank containing approximately 4,000 eggs and embryos belonging to at least 950 families."We currently represent well over 100 clients whose cases we will pursue as individual claims. That number is growing by the day," Cleveland attorney Tom Merriman said Monday.Also Monday, attorney Gloria Allred threw her hat into the ring, announcing litigation on behalf of three Pittsburgh women who are all cancer survivors. 567