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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

LOS ANGELES, July 6 (Xinhua) -- NASA scientists have got the first-ever, up-close details of a Saturn storm that is eight times the surface area of Earth, the Jet Propulsion Laboratory ( JPL) announced on Wednesday.The images were captured by NASA's Cassini spacecraf, according to JPL in Pasadena, Los Angeles.On Dec. 5, 2010, Cassini first detected the storm that has been raging ever since. It appears approximately 35 degrees north latitude of Saturn.The storm is the biggest observed by spacecraft orbiting or flying by Saturn. NASA's Hubble Space Telescope captured images in 1990 of an equally large storm.Pictures from Cassini's imaging cameras show the storm wrapping around the entire planet covering approximately two billion square miles (4 billion square kilometers).The storm is about 500 times larger than the biggest storm previously seen by Cassini during several months from 2009 to 2010. At its most intense, the storm generated more than 10 lightning flashes per second.Cassini has detected 10 lightning storms on Saturn since the spacecraft entered the planet's orbit.Those storms rolled through an area in the southern hemisphere dubbed "Storm Alley." "Cassini shows us that Saturn is bipolar," said Andrew Ingersoll, a Cassini imaging team member at the California Institute of Technology in Pasadena, California. "Saturn is not like Earth and Jupiter, where storms are fairly frequent. Weather on Saturn appears to hum along placidly for years and then erupt violently. I'm excited we saw weather so spectacular on our watch."The new details about this storm complement atmospheric disturbances described recently by scientists using Cassini's composite infrared spectrometer and the European Southern Observatory's Very Large Telescope. The Cassini-Huygens mission is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. NASA's JPL manages the mission for the agency's Science Mission Directorate in Washington.

LOS ANGELES, June 3 (Xinhua) -- Eating earth may protect the stomach against toxins, parasites and pathogens, a new study suggests.To examine the possible benefits from eating earth, researchers at Cornell University analyzed reports from missionaries, plantation doctors, explorers, and anthropologists to put together a database of more than 480 cultural accounts of geophagy -- the eating of earth.The database includes as many details as possible about the circumstances under which earth was consumed, and by whom. The researchers could then use patterns in the data to evaluate each potential explanation.Studies in the database indicate that geophagy is common even when food is plentiful. Moreover, when people eat dirt they tend to eat only small quantities that are unlikely to fill an empty stomach.The database shows that geophagy is documented most commonly in women in the early stages of pregnancy and in pre-adolescent children. Both categories of people are especially sensitive to parasites and pathogens, according to the researchers.In addition, geophagy is most common in tropical climates where foodborne microbes are abundant. Finally, the database shows that people often eat earth during episodes of gastrointestinal stress.It's unlikely the intestinal problems are caused by the dirt itself because the type of clay people usually eat comes from deep in the ground, where pathogens and parasites are unlikely to contaminate it. Plus, people usually boil the clay before eating it.More study would be helpful to confirm the protection hypothesis, the researchers say, but the available data at this point clearly support it over the other explanations for eating earth."We hope this paper stimulates (more) research," said Sera Young, a researcher at Cornell University and the study's lead author. "More importantly, we hope readers agree that it is time to stop regarding geophagy as a bizarre, non-adaptive gustatory mistake.""With these data, it is clear that geophagy is a widespread behavior in humans ...that occurs during both vulnerable life stages and when facing ecological conditions that require protection."The study is appearing in the June issue of The Quarterly Review of Biology.

URUMQI, Sept. 5 (Xinhua) -- The first China-Eurasia Expo that concluded Monday in Urumqi, capital of northwest China's Xinjiang Uygur Autonomous Region, has clinched trade and technical cooperation contracts worth about 130 billion U.S. dollars, expo organizer said.Among all contracts, 5.5 billion dollars are clinched between Chinese and foreign companies, while 124 billion dollars are among Chinese companies, the organizer said.About 50,000 officials and business people from China and about 30 countries, regions and international organizations attended the trade fair, which also attracted an audience of more than 300,000 people.The event was upgraded from the 19-year-old China Urumqi Foreign Economic Relations and Trade Fair, a regional trade fair, last year.The fair covered an area of nearly 80,000 square meters for its more than 4,000 exhibition booths, according to the organizer.

SYDNEY, June 29 (Xinhua) -- A type of dried seaweed sold in Asian food supermarkets in Australia has been recalled after it was found to have high levels of iodine dangerous to pregnant women, local media reported on Wednesday.Food Standards Australia New Zealand (FSANZ) has ordered the recall of Wang Dried Kelp Varech Speche, a Korean brand of the dried seaweed, according to Australian Associated Press (AAP).It has been available in Asian grocery stores and restaurants in the Brisbane and Gold Coast areas of Queensland."The product contains high levels of naturally occurring iodine," FSANZ said in a statement."Regular consumption of these products may cause health problems in some people including pregnant and breastfeeding women."FSANZ said consumers concerned about their health should seek medical advice and should return the products to the place of purchase for a full cash refund.

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