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SAN DIEGO (KGTV) — At least six companies are working on COVID-19 vaccine candidates in San Diego, all within a 1.5-mile radius of where the I-5 and I-805 split.Locally, the farthest along appears to be Inovio Pharmaceuticals, which plans to launch a Phase 2 trial next month, potentially with a simultaneous Phase 3 trial. A Phase 3 trial is the final step in vaccine testing, with thousands of participants.The company is developing the vaccine using a DNA technique that isn’t used in any other vaccines on the market, although some are in the final stages of testing, said Dr. Kate Broderick, who leads Inovio’s vaccine program.To ensure the DNA enters a person’s cells, the company uses a proprietary device about the size of a toothbrush to deliver doses into the skin rather than a needle and syringe. The company announced Tuesday it secured a million grant from the Department of Defense to speed up production of the devices.Just down the street, TriLink Biotechnologies is working with researchers in London on a vaccine candidate that replicates itself in the body. It just started a Phase 1 trial this month.Nearby, Sorrento Therapeutics is working on both a COVID-19 vaccine and a treatment, but it hasn’t advanced yet to human trials. 10News previously featured the company’s efforts, which are based on techniques developed to fight cancer.On the other side of the 805, Arcturus Therapeutics is working with Duke University on a vaccine based on RNA, which acts as a messenger for DNA. There are no vaccines approved for humans that use this RNA approach. Trials are expected to begin in August, according to a tracker by the Milken Institute.UC San Diego is developing a vaccine using plant virus nanotechnology, leveraging an approach that’s used in vaccines against Hepatitis B and shingles. The university is also taking part in research on a COVID treatment.A spokeswoman for San Francisco-based Vir Biotechnology says the company is using its San Diego satellite office to help crunch data for the work on its vaccine, which is a collaboration with GlaxoSmithKline (GSK).GSK, Janssen, and Pfizer each have vaccine candidates of their own and offices near the 5-805 split, but 10News was not able to immediately confirm if any of those companies were conducting COVID research locally. 2318

SAN DIEGO (KGTV) — County supervisors and health officials say the region's number of community outbreaks has exceeded its threshold prompting a pause on future business reopenings.Thursday, community outbreaks rose to eight from June 11-17. A community outbreak is considered three or more confirmed cases from the same place.The community outbreaks were linked to three businesses, two restaurants, one private residence, one campground, and one social club, according to Public Health Officer Wilma Wooten. RELATED: California requiring face coverings for most indoor areas"People are gathering and not using facial coverings," Wooten said. "When people come together and are within 6 feet of each other without facial coverings it's bound to happen."As things open up and people think that they can go back to the pre-COVID-19 existence, we cannot."Three of the eight outbreaks could fall off the county's metrics on Friday and bring the county below the threshold once again.Supervisor Nathan Fletcher said the following actions would be taken in response:The county will pause implementing statewide guidance on additional reopenings, not including Friday's planned reopenings of nail salons and other personal care services; andThe county would begin targeted enforcement on entities that are not following health orders.The locations of the county's eight outbreaks were not detailed. Fletcher said revealing which businesses had outbreaks could jeopardize contact tracing reporting and businesses cooperating. He added that the county is working with those businesses on their precautions and if there is a great enough risk, further details — including locations — could be released to the public.Fletcher said that the outbreaks were spread around the county, not directly linked to one another, and no deaths have been associated with them.RELATED: Mayor releases outdoor dining proposal in Little ItalyReferencing photos captured last weekend in downtown San Diego showing many visitors at bars not wearing masks or distancing, Fletcher said the county is counting on businesses to help enforce local orders."There is significantly less concern about individuals outdoors than indoors," Fletcher said. "We are really dependent on business owners to enforce the protocols in their businesses."Officials encouraged facial coverings, washing hands frequently, avoiding large private or public gatherings, and staying home when sick to fight future community outbreaks. 2486

SAN DIEGO (KGTV) - At least two former students of a coding bootcamp in downtown San Diego received refunds after a Team 10 story earlier this summer.Sean Calma and Lane, who declined to give his last name, were enrolled at Origin Code Academy. They both said they were promised one-on-one instruction, which they did not receive. Neither had previous coding experience, so they both asked many questions before enrolling."One time, [the instructor] didn't even know what he was looking at on my computer screen. A second time, he was like, I don’t know what that is. Third time, he asked to go ask another instructor," Lane told Team 10 back in June.CEO Jeff Winkler said coding is difficult, but would be willing to talk to the students about getting their money back. During a previous Team 10 interview, he pointed to many satisfied students and dozens of graduates, including one who recently got a job at Facebook.Winkler did not respond to Team 10's request for comment regarding the refunds.Coding bootcamps are regulated by the Bureau for Private Postsecondary Education (BPPE). Origin Code Academy was previously operating without approval. The academy appealed its citation, its fine was reduced, and as of August, it is allowed to operate. As part of its approval, it had to pay back students who asked for refunds.Both Calma and Lane could not talk about their refunds the received after Team 10's story because both had to sign a non-disclosure agreement before getting their money back.A spokesperson for the BPPE told Team 10: "The Bureau encourages Origin Code Academy students who have not yet received a requested refund to contact the Bureau so we can investigate their claims. If any of the subjects in your story are still waiting for refunds please encourage them to reach out." 1809

SAN DIEGO (KGTV) -- Bike the Bay celebrated its 11th annual ride on Sunday but this year it added some safety changes. Roughly 3,000 people participated in the popular bike ride. The ride is 25 miles and takes cyclists over the Coronado Bridge, through Coronado, Imperial Beach, Chula Vista and National City. It's the only day of the year where bikes are allowed on the iconic bridge. This year, the event made some changes after an accident during the ride last year. Christina Rocheleau who was not participating in the ride collided head-on with a participant who was trying to pass cyclists along the trail. Rocheleau suffered a fractured nose and three fractured vertebrae. She hasn't been on a bike since. At the time of the accident, organizers told us that they take safety very seriously. This year, they added more signs along the route, more volunteers to guide cyclists and made the route all one-way. All of the proceeds for the ride go towards the San Diego County Bike Coalition, an organization that promotes bicycles as a form of transportation and advocates for safer roads for cyclists.   1156

SAN DIEGO (KGTV) — Days after revealing its move to downtown San Diego's Petco Park, KAABOO announced it's under new ownership.KAABOO's new owner, Virgin Fest, the music festival arm of The Virgin Group, will not change the festival's brand of live music, comedy, art, and culinary experiences, KAABOO said in a release.While Virgin Fest Founder and CEO Jason Felts has acquired all of the festival's assets, KAABOO San Diego itself will also not be rebranded. Felts formerly served as a partner and chief brand officer at KAABOO.RELATED: KAABOO music festival moving to Petco Park in 2020"We’ve been delighted to entertain hundreds of thousands of live entertainment fans," KAABOO Co-Founders Bryan Gordon and Seth Wolkov. "We are appreciative of Richard and Virgin’s early support of our brand and confident that in Jason and his team’s capable hands, the journey that we started to offer adults a truly differentiated festival experience is sure to live on and grow for many years to come."KAABOO says it will continue to look for ways to offer more live experiences and activations.This week, the festival announced its move to Petco Park in 2020, after spending its first five years at the Del Mar Fairgrounds.RELATED: San Diego's Wonderfront fest adds Migos, J.I.D., surprise band“The location of Petco Park and its surrounding venues in downtown San Diego provides fans and artists alike the opportunity to enjoy everything that the vibrant metro area has to offer. We couldn’t be more ecstatic about this partnership and our relocation,” said Felts.The three-day festival plans to feature concerts at Petco Park's playing field, Sycuan Stage at the Park, Lexus Premier Lot, and the Tailgate Lot. The festival also plans to continue offering comedy, art, and culinary experiences at the stadium.KAABOO San Diego is set for Sept. 18-20, 2020. Tickets are on sale now, starting at 9 for a three-day pass. 1945