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BEIJING, July 26 (Xinhuanet) -- Seven of the 20 top selling American prescription drugs will lose their patents by the end of next year, making way for less expensive generic versions, according to media reports.It's a shift that could save consumers billions of dollars -- assuming those big-ticket medications are willing to give up a trusted brand name for an off-label replacement.The prices of medications such as cholesterol-fighting Lipitor and blood thinner Plavix are expected to go down significantly, according to the U.S. Food and Drug Administration (FDA).Lipitor will lose its patent in November. When that patent expires, people are advised to buy atorvastatin, the generic equivalent. Other brand names include the anti-psychotic Zyprexa and the rheumatoid arthritis and psoriasis drug Enbrel, of which the patent will expire in October and October of next year, respectively.Over the next 10 years, an estimated 120 more brand-name prescription drugs will lose their patents in the U.S.
LOS ANGELES, June 20 (Xinhua) -- About 8 percent of children, or nearly 6 million in the U.S., have a food allergy, a much higher rate than previously estimated, a new study suggests.Not only is this estimate higher than some previous research has reported, allergic reactions are often severe and that many kids have more than one allergy, according to the study published online in Pediatrics on Monday.Of the children with confirmed (or probable) food allergies, about 39 percent had had severe reactions in the past, and 30 percent had more than one allergy, the study found.In the current study, researchers at the Northwestern University Feinberg School of Medicine surveyed parents of more than 38,000 children about whether their child had been diagnosed with a food allergy and had one or more of a number of symptoms, including anaphylaxis; swelling of the lips, eyes or face and skin rashes or hives.The study pinned down peanuts (25 percent of food-allergic children), milk (21 percent) and shellfish (17 percent) as the top three allergens.Severe reactions were most common among children with tree nut (more than 50 percent) and fin fish (more than 40 percent) allergies. The reactions were more likely among 14- to 17-year- olds compared with 0- to 2-year-olds, and more likely in children with multiple food allergies, the study found."These findings provide critical epidemiologic information to guide strategies for the prevention of food-induced reactions and for the diagnosis and management of childhood food allergies," the study noted.

BEIJING, Aug. 12 (Xinhuanet) -- The risk of developing coronary heart disease is 25 percent higher for women smokers compared with men, according to a study published in the British medical journal "The Lancet".The authors say this could be due to the physiological differences between the sexes with cigarette smoke toxins having a more potent effect on women.The study by Dr Rachel R Huxley from the University of Minnesota and Dr Mark Woodward from Johns Hopkins University involved a meta-analysis of around four million individuals and 67,000 coronary heart disease events from 86 studies.The researchers found that the pooled adjusted female-to-male relative risk ratio (RRR) of smoking compared with not smoking for coronary heart disease (CHD) was 1.25 (25 percent) higher for women.This RRR increased by 2 percent for every additional year of follow-up, meaning that the longer a woman smokes, the higher her risk of developing CHD becomes compared with a man who has smoked the same length of time.The authors say, "The finding lends support to the idea of a pathophysiological basis for the sex difference. For example, women might extract a greater quantity of carcinogens and other toxic agents from the same number of cigarettes than men. This occurrence could explain why women who smoke have double the risk of lung cancer compared with their male counterparts."Worldwide, there are 1.1 billion smokers, of whom a fifth are women.According to the Tobacco Atlas, India, with around a crore female smokers, ranks third in the top 20 female smoking populations across the globe, only the U.S. with 2.3 crore female smokers and China with 1.3 crore female smokers, are worse off.
WASHINGTON, Aug. 4 (Xinhua) -- Observations from NASA's Mars Reconnaissance Orbiter have revealed possible flowing water during the warmest months on Mars, the U.S. National Aeronautics and Space Administration (NASA) announced Thursday.Dark, finger-like features appear and extend down some Martian slopes during late spring through summer, fade in winter, and return during the next spring. Repeated observations have tracked the seasonal changes in these recurring features on several steep slopes in the middle latitudes of Mars' southern hemisphere."The best explanation for these observations so far is the flow of briny water," said Alfred McEwen of the University of Arizona, Tucson.McEwen is the principal investigator for the orbiter's High Resolution Imaging Science Experiment and lead author of a report about the recurring flows to be published in Friday's edition of the journal Science.Seven such sites on the planet have been confirmed, with 20 more possible, McEwen said."What makes these new observations so interesting is they occur at much lower latitudes where temperatures are much warmer and where it's actually possible for liquid water to exist," said Arizona State University geophysicist Phil Christensen, one of the scientists who studied the images beamed back from the orbiter.The study does not prove water exists, but identifies it as the best explanation. It's worthwhile to think about alternative reasons for these observations, but none seems to fit as well as briny water, McEwen said."I think it's going to be laboratory experiments on Earth that give us the best confirmation or refutation," he said.
来源:资阳报