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WASHINGTON, May 11 (Xinhua) -- Johns Hopkins University researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.The work, published Wednesday in the journal Science Translational Medicine, suggests that liver cells derived from so- called "induced-pluripotent stem cells (iPSCs)" could one day be used as an alternative to liver transplant in patients with serious liver diseases, bypassing long waiting lists for organs and concerns about immune system rejection of donated tissue."Our findings provide a foundation for producing functional liver cells for patients who suffer liver diseases and are in need of transplantation," says Yoon-Young Jang, assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "iPSC-derived liver cells not only can be generated in large amounts, but also can be tailored to each patient, preventing immune-rejection problems associated with liver transplants from unmatched donors or embryonic stem cells." A microsopic view shows human embryonic stem cells in various stages of differentiation into liver cells in this photo taken at Stanford University and released by the California Institute for Regenerative Medicine, March 9, 2009iPSCs are made from adult cells that have been genetically reprogrammed to revert to an embryonic stem cell-like state, with the ability to transform into different cell types. Human iPSCs can be generated from various tissues, including skin, blood and liver cells.Although the liver can regenerate in the body, end-stage liver failure caused by diseases like cirrhosis and cancers eventually destroy the liver's regenerative ability, Jang says. Currently, the only option for those patients is to receive a liver organ or liver cell transplant, a supply problem given the severe shortage of donor liver tissue for transplantation. In addition, mature liver cells and adult liver stem cells are difficult to isolate or grow in the laboratory, she says. By contrast, iPSCs can be made from a tiny amount of many kinds of tissue; and the embryonic stem- like iPSCs can grow in laboratory cultures indefinitely.For the study, Jang and colleagues generated human iPSCs from a variety of adult human cells, including liver cells, fibroblasts ( connective tissue cells), bone marrow stem cells and skin cells. They found that though the iPSCs overall were molecularly similar to each other and to embryonic stem cells, they retained a distinct molecular "signature" inherited from the cell of origin.

BEIJING, Feb. 3 (Xinhua) -- Thursday marked the welcoming of the Chinese Lunar New Year, or Spring Festival. Celebrations for the Year 2011, also Year of the Rabbit, have been held all over the world, making the Chinese New Year a brilliant symbol in the world's culture.The Chinese New Year is a good opportunity for China and the world to get closer and enhance their friendship. The celebrations also provided a precious occasion for people outside China to feel the unique charm of Chinese culture.In New York, the iconic Empire State building was illuminated in red and gold to mark the Chinese New Year.Chinese handicrafts including festive lanterns, florid Spring Festival paintings and red paper-cut were displayed in the windows on the first floor of the iconic 1,454-foot tall building.Martin Corie, a local resident, said the sea of redness and the strong festival flavor made him feel like being in China.In Paris, a colorful parade featuring music and dancing in the 13th arrondissement in the southern part of the city, attracts more than 100,000 people each year.On Wednesday night, or Lunar New Year's Eve, a special program featuring Chinese folk music was broadcast by the national Radio France.In Cairo, a cultural temple fair was held in Al-Azhar Park. Local visitors were greatly attracted by performances of the Chinese Suona horn (a woodwind instrument) and Chinese traditional art "shadow play." They also enjoyed Chinese embroidering and the practice of the traditional Chinese medical science.

SAN FRANCISCO, March 22 (Xinhua) -- Apple Inc. on Tuesday announced that iPad 2, the second-generation of its popular tablet computer, will be available in China's Hong Kong, Korea, Singapore and additional countries and regions in April.The company also confirmed that iPad 2 will go on sale in 25 countries on March 25 in addition to the United States, where the device first hit market on March 11 and has seen strong demand."While competitors are still struggling to catch up with our first iPad, we've changed the game again with iPad 2," Steve Jobs, Apple's chief executive officer, said in a statement."We're experiencing amazing demand for iPad 2 in the U.S., and customers around the world have told us they can't wait to get their hands on it. We appreciate everyone's patience and we are working hard to build enough iPads for everyone," he noted.Apple had planned to released iPad 2 in Japan on March 25, but delayed the launch in the aftermath of the catastrophic March 11 earthquake and ensuing tsunami in the country.The 25 countries where iPad 2 will go on sale on March 25 include Australia, Austria, Belgium, Canada, the Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Luxembourg, Mexico, the Netherlands, New Zealand, Norway, Poland, Portugal, Spain, Sweden, Switzerland and Britain.

BERLIN, May 26 (Xinhua) -- German health officials said Thursday that cucumbers imported from Spain was one source of a recent deadly E. coli outbreak in northern states that killed three people and made hundreds sick.The Hamburg Institute for Hygiene and the Environment (HU) found that four cucumbers in a local market were contaminated by Enterohaemorrhagic E. coli (EHEC), and three of them were imported from two separate Spanish suppliers, Hamburg state health authorities said.The origin of the fourth cucumber was still under investigation, officials added.German supermarkets began to pull Spanish cucumbers off shelves Thursday afternoon following the findings in Hamburg. The food- monitoring agencies in the northern states were launching investigations on vegetable markets, the federal agriculture ministry said in a statement.Figures showed that Spain is Germany's second largest supplier of cucumbers within the European Union, accounting for some 40 percent of the country's cucumber imports.Scientists said that EHEC is a virulent strain of gut bacterium that can cause severe stomach upsets, diarrhea, stroke and coma. It would lead to kidney failure in extreme cases.Germany saw a terrible E. coli outbreak two weeks ago, starting from the northern states like Hamburg and then spreading to eastern and southern regions. German health authorities said that at least three people have died from infections, and more than 200 have been diagnosed with hemolytic-uremic syndrome (HUS), which is caused by EHEC.Germany's national disease centre, the Robert Koch Institute, suggest people avoid eating raw tomatoes, cucumbers and lettuce for a while.

PARIS, April 22 (Xinhua) -- Heavy load launcher Ariane 5 lifted off two communication satellites, Yahsat Y1A and Intelsat New Dawn, at around 6:37 p.m. local time (2137 GMT) on Friday from Europe's Spaceport in French Guiana.Yahsat Y1A is the first United Arab Emirates satellite launched by Arianespace. It is built by Astrium and Thales Alenia Space and will be positioned at 52.5 degrees East. With a design life of 15 years, it will be operated by the Al Yah Satellite Communications Company, a telecommunications company indirectly controlled by the Abu Dhabi Government.Weighing around 5,935 kilograms at lift-off, Yahsat Y1A was expected to be separated first around 27 minutes after the launcher started the flight.The second passenger Intelsat New Dawn was built by Orbital Sciences Corporation and weighs about 3,000 kilograms. Also with a designed life span of 15 years, it is planned to be positioned at 32.8 degrees East.Via the second mission of Ariane 5 in 2011, Yahsat Y1A will provide customized relay services for the government and commercial sectors in the Middle East, Africa, Europe and Southwest Asia, while Intelsat New Dawn will work as a part of the global Intelsat fleet, offering service for Africa.This launch, the 201st of an Ariane family vehicle since 1979, brought to 22 the number of Intelsat satellites serving Africa, according to the launching company.Originally scheduled for liftoff on March 30, this dual-payload mission was delayed following an interruption of the final countdown when an incorrect displacement of one of the engine's actuators was detected, Arianespace said in a statement. The launching center planned to have six liftoffs of Ariane 5 through this year.

来源：资阳报