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WASHINGTON, April 3 (Xinhua) -- Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the American Association for Cancer Research's 102nd Annual Meeting 2011, held in Orlando, Florida on April 2-6.Katherine McGlynn, a senior investigator at the National Cancer Institute, said approximately one-third of the U.S. population has metabolic syndrome, which is defined as the co-occurrence of at least three of the following five conditions: raised blood pressure, elevated waist circumference, low HDL or "good" cholesterol, raised triglyceride levels and raised fasting plasma glucose levels.According to McGlynn, persons with these conditions may be at increased risk of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma.For the current study, researchers identified 3,649 cases of hepatocellular carcinoma and 743 cases of intrahepatic cholangiocarcinoma. They compared the medical history of these patients with the medical histories of 195,953 cancer-free adults.Statistical analyses showed that the persons with liver cancer were significantly more likely than cancer-free persons to have a prior history of metabolic syndrome: 37.1 percent of patients with hepatocellular carcinoma had pre-existing metabolic syndrome, as did 29.7 percent of patients with intrahepatic carcinoma; only 17.1 percent of the cancer-free adults had metabolic syndrome.Liver cancer incidence has been rising since the 1980s in the United States. The factors related to the increase are not well understood. "A lot of attention has focused on viral risk factors, but a significant part of the increase may be due to metabolic syndrome, as well as to diabetes and obesity," said McGlynn."The prognosis for liver cancer is only marginally better than the prognosis for pancreatic cancer, with a five-year survival of approximately 10 percent," she said. "Prognosis is more favorable, however, when liver cancers are diagnosed at early stages when they are small and localized to the liver."
BEIJING, Jan. 21 (Xinhua) -- Chinese authorities issued an order on Friday to crack down on various election irregularities prior to the upcoming election of a new term of party committees, people's congresses, governments and political consultative conferences at provincial, city, county and township levels.The Central Commission for Discipline Inspection and the Organization Department of the Communist Party of China Central Commission jointly issued the order to guarantee an honest and orderly election.The order says election irregularities, such as winning votes through pulling strings with voters, or bribing key officials who have a say on one's promotion, or manipulating votes by means of threat or deceit, are strictly frobidden.The order also prohibits officials from favoring candidates who are family members or friends, or disclosing election-related information which might alter the results of elections.China holds local elections for party committees, people's congresses, governments and political consultative conferences every five years.
BEIJING, Jan. 22 (Xinhua) -- The Chinese central government in Beijing pledged Saturday that it would work to ensure smooth and safe traveling for the public as many return home to reunite with families during the Spring Festival.It is expected that some 700 million people are to travel during a 40-day Spring Festival travel period that began Wednesday, but heavy snow and icy rain, which has continued since the new year began, has disrupted traffic and cut water and power supplies to some regions in south and southwest China.The lingering freezing weather also poses great challenges to transportation and railway authorities, as they work to avoid another travel disaster, as was seen in early 2008 when unprecedented heavy snow and freezing rain inundated the south of the country, bringing traffic to a standstill at the peak holiday season.Due to this, the Ministry of Public Security announced on Saturday that it had drawn upon the experiences gained from the 2008 weather disaster, and has ordered local bureaus to begin planning precautionary measures to combat the freezing weather.It also issued orders to local departments beginning in late December to step up snow clearance and make sure expressways and key trunk lines are not closed by snow."More police will be deployed to maintain traffic order and security, and to reduce offences such as drunk driving, speeding, passenger overloading of cars and trucks, and driving while fatigued," Huang Ming, Vice Minister of Public Security, said in a press conference held in Beijing.Meanwhile, over 8,300 service stops would be established across the country in order to provide necessities such as water and medical help to drivers and migrant works returning home for the festival.China's meteorological authority forecast Saturday that snowy weather will weaken in most regions over the next three days, but the eastern areas in southwest China will continue to see more rain and snow.On Sunday, the weather forecast anticipated that moderate snow would hit some regions in Inner Mongolia, Guangxi, and Hainan, as the southwestern province of Guizhou will see more icy rain.Local authorities said nearly 10 million have been affected in Hunan after a blizzard that started Monday, which also forced the evacuation of 73,000 people. About 15 power lines were shut down and 132 roads were closed because of snow and icy rain in Guangxi.As the freezing weather makes travel on roads more difficult, railway stations are seeing surges in passenger numbers.An official with the Ministry of Railways (MOR) said nearly 4.8 million passengers took trains on Jan. 19, the first day of the travel peak season this year, up 11.9 percent compared to the corresponding day last year. The next day, over 4.9 million passengers traveled on railways, up 17.5 percent. The Nanchang railway station even saw passenger number jump 30 percent.The MOR said earlier that it would run an additional 293 pairs of trains per day during the rush period in order to meet climbing passenger demand.Further, the Vice Minister of the country's National Development and Reform Commission, the country's top economic planning body, said the ministry would work with other government departments to implement multiple measures in maintaining a stable supply of coal, electricity, oil, and gas so that residents' demands for heating and power use can be met during the festival.The traditional Chinese Spring Festival, or chun jie in Chinese, is the country's most important festival. It falls on Feb. 3 this year. Workers nationwide enjoy a seven-day holiday that ends on Feb. 8.
WASHINGTON, April 25 (Xinhua) -- Study by scientists at the Rockefeller University shows that anti-inflammatory drugs reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors (SSRIs), taken for depression and obsessive-compulsive disorder and anxiety disorders.This discovery, published online Monday in the Proceedings of the National Academy of Sciences, may explain why so many depressed patients taking SSRIs do not respond to antidepressant treatment and suggests that this lack of effectiveness may be preventable.The study may be especially significant in the case of Alzheimer's disease. Such patients commonly suffer from depression and unless this can be treated successfully, the course of the illness is likely to be more severe. Depression in the elderly is also a risk factor for developing Alzheimer's Disease and researchers have suggested that treating depression in the elderly might reduce the risk of developing the disease.In the recent study, investigators treated mice with antidepressants in the presence or absence of anti-inflammatory drugs. They then examined how the mice behaved in tasks that are sensitive to antidepressant treatment. They found that the mice's behavioral responses to antidepressants were inhibited by anti- inflammatory/analgesic treatments.They then confirmed these effects in a human population. Depressed individuals who reported anti-inflammatory drug use were much less likely to have their symptoms relieved by an antidepressant than depressed patients who reported no anti- inflammatory drug use. The effect was rather dramatic since, in the absence of any anti-inflammatory or analgesic use, 54 percent of patients responded to the antidepressant, whereas success rates dropped to approximately 40 percent for those who reported using anti-inflammatory agents."Many elderly individuals suffering from depression also have arthritic or related diseases and as a consequence are taking both antidepressant and anti-inflammatory medications. Our results suggest that physicians should carefully balance the advantages and disadvantages of continuing anti-inflammatory therapy in patients being treated with antidepressant medications," leader author Paul Greengard said.
WASHINGTON, March 9 (Xinhua) -- U.S. space shuttle Discovery landed safely at the Kennedy Space Center in Florida on Wednesday, ending its nearly 27-year flying career as the world's most- traveled spaceship.According to NASA, Discovery touched down at 11:57 a.m. EST ( 1657 GMT) after a 13-day resupply mission to the International Space Station (ISS)."For the final time: wheels stop," Discovery's commander Steven Lindsey called out as the shuttle rolled to a full stop.Discovery lifted off on Feb. 24 from the Kennedy Center and arrived at the space station on Feb. 26.During the mission, the astronauts installed a spare closet module on the space station, completed some important repairs and delivered the first humanoid robot, though it will need more time to be assembled and made operational.The 330-pound R2 consists of a head and a torso with two arms and two hands. Once it is unpacked -- likely several months after its arrival at the station -- it will initially be operated inside the Destiny laboratory for operational testing, but over time both its territory and its applications could expand.Aboard the station, its primary job for now is teaching engineers how dexterous robots behave in space. However, the hope is that through upgrades and advancements, it could one day venture outside the station to help spacewalkers make repairs or additions to the station or perform scientific work.