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WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.

LOS ANGELES, July 5 (Xinhua) -- NASA's Juno spacecraft is 30 days away before its first launch window opens, the Jet Propulsion Laboratory (JPL) announced on Tuesday."One month from today, our first launch window opens at 11:34 a. m. EDT (8:34 a.m. PDT) and lasts 69 minutes," said Jan Chodas, Juno project manager from NASA's JPL in Pasadena, Los Angeles."Our primary launch period is 22 days long, and so if weather or other issues come up on Aug. 5, we have 21 more days to get Juno flying. Once we get Juno into space, it's a five-year cruise to Jupiter.""The launch window is the length of time allotted every day for an attempt to launch the spacecraft," said Chodas. "The launch period is the period of time in days when everything is in the right place to get your mission off to the right start."For a mission like Juno, getting everything in the right place includes considering the size of the rocket and spacecraft, where our home planet -- and in particular Juno's launch pad -- is pointed at any moment, and its location in space relative to other celestial objects like Juno's final target, Jupiter.Juno is scheduled to launch aboard a United Launch Alliance Atlas V rocket from pad 41-C at the Cape Canaveral Air Force Station, Florida.The solar-powered spacecraft will orbit Jupiter's poles 33 times to find out more about the gas giant's origins, structure, atmosphere and magnetosphere and investigate the existence of a solid planetary core.JPL manages the Juno mission for the principal investigator, Scott Bolton, of Southwest Research Institute in San Antonio.The Juno mission is part of the New Frontiers Program managed at NASA's Marshall Space Flight Center in Huntsville, Alaska. Lockheed Martin Space Systems, Denver, built the spacecraft.

BEIJING, Aug. 31 (Xinhuanet) – The pressure of modern society is taking a toll on sexual satisfaction, experts say following the release of an online survey.About 34 percent of people polled in the survey said that they are unsatisfied with their sex lives, with 6.5 percent "very unsatisfied".Another 32 percent condemned their sex lives as "just so-so".The survey interviewed more than 3,000 people, aged between 15 and 55, with men accounting for 74 percent of the interviewees.It was conducted by the China Population Communication Center and the Shanghai Academy of Social Sciences from May 1 to June 20. The survey did not give a margin of error.Only 23 percent of respondents said that they are "satisfied" with their sex lives, with 3.6 percent "very satisfied", according to the survey.But women seem to have a higher rate of satisfaction than men, with only 26 percent saying they are unsatisfied. The rate for men is 42 percent.The rate of sexual satisfaction among Chinese people is below the global average of 44 percent, according to an earlier survey by Durex. The 2007 Durex Global Sexual Wellbeing Survey questioned more than 26,000 people in 26 countries about all aspects of their sex lives - including satisfaction levels.Jiang Hui, president-elect of the Chinese Society of Andrology, attributed the lower rate of sexual satisfaction among Chinese people to rapid economic growth, which inevitably increases work and social pressure.Health problems associated with a modern lifestyle, such as diabetes and hypertension, are also to blame, he said.Jiang said his department of andrology used to receive about 10 patients a day 10 years ago. Now the figure has risen to more than 250.Rising awareness of sex and a more open attitude toward the once-taboo topic among the public also contributed to higher sexual expectations, he said.The survey also revealed that about 30 percent of respondents in the 35-55 age group had sex less than once a week."That rate is quite low, compared with the global average of 103 times a year, or 1.98 times a week," said Yang Xiong, who heads the social survey center at the Shanghai Academy of Social Sciences.Only 16.9 percent of respondents said that they had sex more than 10 times a month. Most respondents had sex three to nine times every month.About 8 percent of respondents said that they basically had no sex at all or it was too infrequent to be classified.The survey seemed to find that the more you made, the less you had. Those who earned at least 9,000 yuan (,400) a month had less sex than those who earned less, according to the survey.Among those making more than 9,000 yuan per month, over 70 percent said they had sex less than twice a month, compared with 16.5 percent for those with a monthly salary of less than 6,000 yuan.The survey also found that when people run into problems with their sex lives, 83 percent turn to the Internet, rather than professionals, for help. Less than 6 percent said they would see doctors to solve sex-related problems.Nearly 70 percent of those polled said they suffered from sexual health problems, such as erectile dysfunction (ED)."Many patients, especially men, are reluctant to see a doctor, which they think harms their manhood," Jiang said.According to a study conducted by the Chinese Society of Andrology, at least 40 percent of men aged 40 and above suffered from erectile dysfunction, roughly the global average.But Yang, from the Shanghai academy, noted that surveys conducted online tend to produce far different results than those conducted face-to-face.He expressed reservations about the survey's accuracy and said the public should only use the results for reference.

THE HAGUE, Aug. 16 (Xinhua) -- ESBL-enzymes, which are known for their ability to stop the effects of antibiotics, can directly pass from chicken to people, said a research published on Tuesday.Veterinary researcher Dik Mevius of the Wageningen University released the finding in the magazine Resource.The research group led by Mevius has isolated six ESBL-genes varieties and compared them to bacteria found on hospital patients, on super market poultry and in laying batteries. In 35 percent of all cases, they discovered a match of 100 percent.Bacteria like Klebsiella on E. coli can produce the ESBL-enzymes. A healthy person will not feel any effect, but people with a lower immune system can get very sick. In areas like a hospital, the infection can easily spread."The main concern is that the enzyme resists the most used antibiotics, which makes the treatment of infected persons difficult," said Mevius.According to Mevius, 94 percent of supermarket poultry carries the enzyme, but all enzymes will be killed during the heating process of cooking.

SAN FRANCISCO, July 12 (Xinhua) -- Facebook and Time Warner announced on Tuesday that they are teaming up to launch a wide- ranging, major cross-platform partnership initiative to fight bullying.The multi-media campaign, named "Stop Bullying: Speak Up" after the original anti-bullying initiative by Time Warner's Cartoon Network, will integrate broadcast, print, online and social media to educate parents, teachers and youth about the actions that will help protect young people from the impact of bullying, the two said in a joint statement.As part of the initiative, Facebook is scheduled to launch an interactive application in the back-to-school season this fall, which will enable educators, parents, and kids to make a personal commitment to help stop bullying."We care deeply about the safety of our nation's children and are proud to be partnering with Time Warner to raise awareness of bullying," Sheryl Sandberg, Facebook's chief operating officer, said in the statement."We believe that by working together with parents and teachers, we can teach young people to speak up and stop bullying," she added.Time Warner is also planning to expand its multiplatform efforts to communicate the anti-bullying message to an broader audience.It said in October, three of its magazines -- People, Sports Illustrated and Time -- and their affiliated websites will feature editorial content that highlights the problem of bullying and innovative programs and measures being taken to combat it.In partnership with Facebook, CNN's Anderson Cooper will also host a new town hall, which is scheduled to air in October and will be dedicated to discussing bullying issues confronting kids today as well as discussions with experts to teach adults on coping with the bullying epidemic."I'm confident that through our multiplatform approach and combined resources we can inspire even more people to take action against bullying," said Jeff Bewkes, Time Warner's chairman and chief executive officer.

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