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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).
ROME, Sept. 27 (Xinhua) -- The 30th general assembly of the International Council for Science (ICSU) kicked off here on Tuesday to address key global challenges, featuring over 275 scientists and experts from all over the world.The goal of the four-day event, hosted for the first time in Rome by the National Research Center (CNR) as Italy's scientific member at ICSU, is to discuss how science can contribute to boosting sustainable development, fighting climate change, increasing well-being and health in the changing urban environment and tackling the side-effects of progress.At the official opening ceremony, CNR president Francesco Profumo stressed that scientific research was the key to solving all current crises."It's during times of crises that inventions, great strategies and discoveries are made," he said quoting Albert Einstein."Global cooperation is crucial in addressing society's needs. In the wake of the negative economic outlook we are witnessing research and technological transfer can turn into efficient instruments to guide countries towards a solid development giving us the tools to tackle with lucidity the great obstacles we face," observed Profumo.Appealing to both private and public institutions, Profumo thus urged to boost strategic partnerships between universities, governments and research centres."We must create a network of knowledge-sharing together with enterprises in order to multiply and better implement growth and well-being opportunities. But in order to do so concrete political decisions must be undertaken and financial resources are needed," he added.

BEIJING, Aug. 24 (Xinhuanet) -- Facebook said it is overhauling its privacy settings to give members easier, more precise control over who sees posts, photos and other content over the vast social network.Starting Thursday, Facebook is rolling out new privacy tools that are placed with each piece of content, replacing options that are now buried in overall account settings.Privacy has been a consistently sticky problem for the Palo Alto firm, which has felt the heat from privacy advocates and government regulators. And recently, Facebook faced stiffer competition from Google's new Google+ social network, which was hailed for including a "circles" feature with easy-to-use privacy settings.Instead of vague labels such as "everyone," which have been mistaken for a Facebook member's social network instead of anyone on the Internet, the new system will include more precise words such as "public.""You have told us that 'who can see this?' could be clearer across Facebook, so we have made changes to make this more visual and straightforward," Chris Cox, Facebook's vice president of product, said in blog post."The main change is moving most of your controls from a settings page to being inline, right next to the posts, photos and tags they affect. Plus there are several other updates here that will make it easier to understand who can see your stuff (or your friends') in any context," Cox said.While privacy advocates reserved judgment until the new settings are actually released, they were optimistic the changes will benefit consumers."These changes do make me feel very confident in the direction that Facebook is going and the way they are thinking about privacy," said Erica Newland, policy analyst for the Center for Democracy & Technology in Washington, D.C.
SAN FRANCISCO, Sept. 12 (Xinhua) -- More U.S. Internet users will access Internet through mobile devices than through PCs or other wireline devices by 2015, market research company International Data Corporation (IDC) said in its latest study released on Monday.According to IDC, the number of mobile Internet users will grow by a compound annual growth rage of 16.6 percent between 2010 and 2015, as mobile devices sales, such as smartphones and media tablets, explode."The impact of smartphone and especially, media tablet adoption will be so great that the number of users accessing the Internet through PCs will first stagnate and then slowly decline," said IDC in a forecast.Western Europe and Japan will not be far behind the U.S. in following this trend, the study noted.IDC also predicts that some 40 percent of the world's population will have access to Internet in 2015, when the total number of Internet users will grow to 2.7 billion from 2 billion in 2010."Forget what we have taken for granted on how consumers use the Internet," Karsten Weide, IDC's research vice president of media and entertainment, said in a statement."Soon, more users will access the Web using mobile devices than using PCs, and it's going to make the Internet a very different place," he added.
SAN FRANCISCO, Aug. 10 (Xinhua) -- Amazon on Wednesday launched Kindle Cloud Reader, a web-based app that may help the on-line retailer to sidestep Apple's App Store restrictions.In its announcement, Amazon said Kindle Could Reader uses the HTML5 web standard to let users read e-books from their Kindle library from the Safari browser or Google's Chrome browser on their desktops or tablet, including the iPad.Support for Internet Explorer, Firefox and the Blackberry Playbook will be launched later this year.The app has a button linked to the Kindle Store, which was removed recently from the Kindle apps for iPad and iPhone.The move is taken as an answer to Apple's latest App Store restrictions, which banned developers to have any external links for purchasing digital books or subscriptions in the app, unless they give Apple a 30 percent cut from the in-app sales.Besides Amazon, Barnes & Noble, Google Books and Canadian e- book seller Kobo have also altered their iPad and iPhone apps to comply with the rules.Meanwhile, publishers and retailers have been developing web- based HTML5 apps to sidestep Apple for more control, which is an approved-of technology for iOS devices.The Financial Times, Kobo and video-on-demand service Vudu have recently launched their HTML5 app to avoid paying Apple a 30 percent cut.Industry watchers said it is unknown how Apple will deal with such apps. It would be easy for Apple to disable Web apps in the iPad's Safari browser, but the company would certainly face some backlash, said tech media website CNET.
来源:资阳报