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SAN DIEGO (KGTV) — The National Institutes of Health highlighted research Tuesday out of UC San Diego that could unlock a new way to treat COVID-19.The research reveals new insight into how the coronavirus hijacks cells, and how doctors might be able to set traps or decoys to combat the virus. The findings were published in the journal Cell last month.“It does open up another avenue for a potential treatment,” said UC San Diego distinguished professor Dr. Jeffrey Esko. “It’s not a cure. It would be something that would tamp down infection potentially.”Since January, scientists around the world have understood that SARS-Co-V2, the official name of the new coronavirus, enters cells by latching onto a specific receptor on the cell’s surface, called ACE2.The UCSD team, led by Dr. Esko and visiting scholar Dr. Thomas Clausen, discovered that this entry mechanism is actually a two-step process, and the virus must also attach to a long chain of sugars called heparan sulfate.“We’ve shown this is fundamental to the infectious mechanism, so it needs to be part of every study from now on,” said Clausen.All cells are coated with a complex layer of sugars, or carbohydrates, called glycans. Heparan sulfate is one type of glycan that is known to play a key role in the infection process in several viruses, including herpes and other coronaviruses.It’s a complicated process to picture so the researchers offer an analogy: imagine a bird, soaring over trees, hunting a worm on the forest floor. The bird is the coronavirus and the trees are the thick layer of glycans that coat the surface of the cell.To reach the worm, which in this case is the receptor ACE2, the bird must navigate its way through the trees, specifically through heparan sulfate.The UCSD found that by removing the heparan sulfate trees with an enzyme, they were able to prevent the virus from infecting cells. In laboratory testing, they also found a second technique worked to foil the virus: introducing more trees as bait.The team found that heparin, an FDA-approved drug that is similar in structure to heparan sulfate, successfully acted as decoy. Heparin is a widely used drug designed to treat blood clots. Since blood clots and strokes are common complications with COVID-19, many doctors already administer heparin to patients.The UCSD team demonstrated that the two approaches can block infection in lab-grown cells about 80 to 90 percent of the time.“Certainly in the laboratory you can demonstrate that it works, but to deploy it and use it as a therapeutic has not been demonstrated,” Esko said.The NIH noted that more studies are planned to explore whether heparin, heparan sulfate, or drugs that target heparan sulfate might yield a viable COVID-19 treatment.Dr. Esko said he’s already been in talks with companies that plan to use their study as a rationale for a clinical trial.“It is very humbling when you realize we’re working on a pandemic right now, and maybe what we’ve done can contribute to a treatment for the disease,” he said. 3038

SAN DIEGO (KGTV) -- The Navy confirmed Thursday that the suspected Golden State Killer attended and graduated basic training at the Naval Training Center in San Diego.Officials say Joseph DeAngelo, 72, graduated from the training center after attending from October to December of 1964.DeAngelo also served aboard the Boston-class guided-missile cruiser USS Canberra (pictured below) during the Vietnam War.The Naval Training Center closed in 1997 and is now known as Liberty Station. The San Diego's District Attorney is also reexamining cold cases in San Diego that may have links to DeAngelo. TIMELINE: Major events in Golden State killer caseNew information Thursday also helps paint the picture of how authorities were able to catch the man accused of killing at least 12 people and raping at least 45 women.Prosecutors say authorities used genealogical sites to find a DNA match for DeAngelo, according to the Associated Press.Investigators compared the DNA collected from a crime scene of the Golden State killer to online genetic profiles and found a match: A relative of DeAngelo. Investigators didn't go into further detail such as which company they went through. DeAngelo is accused of committing the murders, rapes and more than 120 burglaries in the decade spanning between 1976 and 1986.RELATED: Suspect identified, arrested in East Area Rapist/Golden State Killer caseMost of the crimes happened near Sacramento and in the Bay Area.The Associated Press contributed to this report. 1544

SAN DIEGO (KGTV) -- The June Primary and November general election are fast approaching. Here are some of the important deadlines to keep in mind.According to the Registrar of Voters, Californians have until 11:59 p.m. on the 15th day before the election to register to vote.If you’re requesting a mail-in ballot, the registrar says it must be returned by 8 p.m. on election day.The primary will be held on June 5 followed by the General Election on November 6.Check out the list below for more dates: 509

SAN DIEGO (KGTV) - The memories came flooding back for Vietnam veteran Ray Hildreth as he returned to Camp Pendleton 50 years later. He wanted to tour his old unit, the 1st Recon Battalion."Looking at the mountains, I remember having to run up and down them!"And while the current 1st Recon Battalion Marines may not recognize Hildreth, they know his story. In June of 1966, Hildreth's unit was stationed on Hill 488 in the jungles of Vietnam. Before the week was over, they would fight the battle that would make them the most highly decorated small unit in the entire history of the U.S. military, winning a Congressional Medal of Honor, four Navy Crosses, thirteen Silver Stars, and eighteen Purple Hearts—some of them posthumously.There were just 18 of them when they encountered the enemy, a battalion of over 200. "Early on in the battle, and all the Marines here can identify with this, the NVA yelled out 'Marines you die in an hour,' and we had some colorful words to say back to them, and said, come and get us," remembers Hildreth.The late Staff Sergeant Jimmie Howard served as platoon leader with 1st Reconnaissance Battalion and led the defense of Hill 488 when attacked by the North Vietnamese.Howard had combat experience from Korea, and Hildreth credits the leader with keeping them alive. "Sergeant Howard said, 'Laugh at them!' And we did, we laughed out loud at them. Later I went back to Vietnam, 2011. I met one of the NVA we fought against. I asked him, what did you think when we laughed at you? He said we thought you were a much bigger unit. And it was that laugh, I'm sure of, that made them not just try to walk over the top of the hilltop and take us," said Hildreth. When they were out of grenades, the men began throwing rocks. "If we hadn't laughed at them, by sheer numbers, they could've walked across the top of the hill and killed us. At the end of the day, there were maybe eight rounds of ammunition left between us."The unit killed an estimated 200 people.Of the 18, all were wounded, and six died. Hildreth wrote a book about the battle, titled Hill 488."I thought people needed to know about the battle, not everyone went over there took drugs and smoked pot," said Hildreth. "We went over there with a different outlook, we're supposed to be here, there's a reason for it, and we done our job. We didn't protest."During the visit, Hildreth was accompanied by some of Staff Sergeant Howard's family members. 2456

SAN DIEGO (KGTV) -- Surveillance video captured the moment after a thief stole a woman's wallet inside a Midway District grocery store.According to San Diego Crime Stoppers, the theft happened on Sept. 23 inside the Ralph’s grocery store located at 3345 Sports Arena Blvd.While the 73-year-old female victim was in the freezer section, the man waited for the victim to open a freezer door and then approached her shopping cart. The suspect quickly removed the victim's wallet from her purse, which was placed at the top of the shopping cart.The victim was right next to the cart but was looking inside a freezer when the theft occurred.The suspected thief walked away without the victim realizing what had happened. The total loss of the wallet and cash inside it is over ,500.Investigators reviewed store surveillance footage, which showed the man following the victim throughout the store and appearing to target her.The suspected thief is described as a white male, approximately 5’10“ tall, 175 lbs., with tanned skin. He was wearing a light-colored baseball cap with black sunglasses on the front of the cap, a light green short-sleeve button-up shirt, gray shorts, and black sandals.Anyone with information should call the San Diego Police Department's Western Division at (619) 692-4800 or the Crime Stoppers anonymous tip line at (888) 580-8477.Crime Stoppers is offering up to a ,000 reward to anyone with information that leads to an arrest. 1463

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