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The US Food and Drug Administration pressed forward with its investigation of e-cigarette companies Friday, sending letters to 21 companies in an effort to uncover whether they are marketing products illegally and outside the agency's compliance policy.This latest phase of the investigation addresses more than 40 e-cigarette products and is part of the agency's ongoing efforts to combat e-cigarette use among youth. It also comes less than two weeks after the agency conducted a surprise inspection of e-cigarette maker Juul's corporate headquarters in San Francisco, seizing thousand of documents, many of which relate to its sales and marketing practices."Companies are on notice," FDA Commissioner Dr. Scott Gottlieb said in a statement Friday. "The FDA will not allow the proliferation of e-cigarettes or other tobacco products potentially being marketed illegally and outside of the agency's compliance policy, and we will take swift action when companies are skirting the law."In September, Gottlieb called the increasing teen use of e-cigarettes "an epidemic," adding that teen nicotine use is dangerous to young people's health and brains.Federal law prohibits the sale of e-cigarettes to people under the age of 18, but more than 2 million middle and high school students were current users of e-cigarettes in 2017, according to the FDA. The US Centers for Disease Control and Prevention says it's the most common nicotine product used by middle and high schoolers.Also last month, the FDA requested that five major e-cigarette manufacturers, including Juul, explain how they plan to combat the use of their products by minors. The agency said it was looking into steps to eliminate the sale of flavored products and unveiled a public education campaignabout e-cigarettes.The FDA said it's considering civil and criminal avenues to enforce these regulations, including fines, seizures and injunctions, according to Friday's announcement.CNN reached out to some of the companies that received letters for comment but did not immediately receive a response."We're going to address issues related to the access kids have to e-cigarettes, as well as the youth appeal of these products," Gottlieb said Friday. "We know flavors are one of the principal drivers of the youth appeal of e-cigarettes and we're looking carefully at this."No reasonable person wants to see these products reaching epidemic use among kids," he said. 2500

The Sanderson Sisters are hoping to put a spell on you, 27 years later.Actress Bette Midler was recently on Fox 5 New York's morning show "Good Day New York" where she confirmed that the original cast of "Hocus Pocus" was reuniting for a sequel.“They want to make a movie, they’ve asked us if we were interested and of course all of us said yes,” Midler said in the interview. “I’m game, I’m totally game.”The movie won’t be the first time the Sanderson Sisters would be reuniting. Midler, Sarah Jessica Parker, and Kathy Najimy are coming together, as their “Hocus Pocus” characters, for a special live, one-night-only virtual event, “In Search Of The Sanderson Sisters,” which is set for Friday. 705

The US has reported more deaths from the coronavirus on Wednesday than in any other single day during the pandemic, according to data from Johns Hopkins University.According to Johns Hopkins’ figures, local health officials reported 3,157 deaths from COVID-19 on Wednesday, shattering the previous record of 2,607 set in April.The marker comes as CDC Director Robert Redfield warned on Wednesday that the US could see an additional 180,000 coronavirus-related deaths between today and the end of January — an average of at least 3,000 a day.Meanwhile, coronavirus hospitalizations in the US topped 100,000 on Wednesday according to the COVID Tracking Project, a mark that is well above the spring and summer surges of the coronavirus. Nearly 13% of all US hospital beds are being used by coronavirus patients, placing the nation’s health care system in a precarious situation.Despite population increases since the 1970s, the number of hospital beds in America has steadily declined, according to CDC figures.Wednesday's figures would likely not include infections that occurred during the Thanksgiving holiday weekend as coronavirus infections can take weeks to cause hospitalizations. Public health experts are fearful that despite some states implementing shutdowns of businesses, that holiday travel will cause an additional spike in coronavirus cases.According to Johns Hopkins, the U.S. has recorded at least 100,000 new COVID-19 cases each day since Nov. 3. 1472

The United States set another record for daily confirmed coronavirus cases as several states posted all-time highs, underscoring the vexing issue confronting President Donald Trump or Joe Biden as a perilous pandemic surges with the holidays and winter approaching. The surging cases and hospitalizations happening around the country reflect the challenge that the winner of the too-early-to-call presidential race will face in the coming months.According to the New York Times, 1,130 coronavirus-related deaths were reported on Tuesday. The average number of deaths, while increasing, is not increasing at the same rate as cases. According to a Harvard risk assessment map, 26 states are are the highest alert level where 25 cases per day per 100,000 people. The states are mostly located in the central US. The map shows that North and South Dakota are experiencing the most widespread cases of the coronavirus. 921

The US House of Representatives passed a federal "right-to-try" bill Wednesday night, leaving many Americans wondering what the move could mean for their health and that of their loved ones.The bill, backed by President Donald Trump, would give terminally ill patients the right to seek drug treatments that remain in clinical trials and have passed phase one of the Food and Drug Administration's approval process, but they have not been fully approved by the FDA.The bill passed the House 267 to 149, after failing to pass last week. Now the legislation needs approval from the Senate.Right-to-try laws exist in 38 states -- Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Michigan, Minnesota, Mississippi, Missouri, Montana, Nevada, New Hampshire, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, West Virginia, Washington and Wyoming -- but this federal bill would introduce legislation across state lines.The central question, however, remains: Would a federal right-to-try bill help or hurt some of the country's most fragile patients? Here's what you need to know, according to experts on both sides of the legislation. 1320