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Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said.  3711

President Donald Trump's tariffs were supposed to shrink America's trade deficit, but it has instead grown for five straight months and is on track to hit a record high before the end of the year.The monthly goods deficit grew by billion in October, according to a US Census report released Wednesday.The Census report is one of the first measures of trade released since Trump imposed his biggest round of tariffs in September on 0 billion of Chinese goods. It put a 10% tax on goods ranging from luggage to bikes and baseball gloves. Trump has threatened to increase the rate to 25% on January 1.The duties make it more expensive for US importers to buy those items, but Americans bought more goods from abroad in October than they did the month before. The figure may reflect stockpiling by American importers ahead of an additional hike in tariffs set to take effect in January, as well as strong consumer spending."There is some anecdotal evidence that US importers are likely pulling forward orders to get ahead of additional tariffs on Chinese goods, which could be one of the factors driving imports higher in recent months," said Pooja Sriram, an economist at Barclays.Last year's federal tax cuts have also put more money back into Americans' pockets, lifting demand for imports even if they're more expensive."We believe that domestic demand is likely to be sufficiently robust so as to keep imports elevated even after any additional tariffs," Sriram said.Additional data due out next week on trade of both goods and services is expected to show a 10-year high in the overall trade deficit, said Ian Shepherdson, chief economist at Pantheon Macroeconomics.That's the opposite of what Trump wants to achieve.The president has pledged to reduce America's trade deficit by pursuing new trade agreements with countries he argues are engaging in unfair trade policies, especially China. He's put tariffs on 0 billion of Chinese-made goods this year in an effort to make US-made products more attractive to consumers."It's been such a terrible one-way street with China," Trump told the Wall Street Journal in an interview Monday.Trump and Chinese President Xi Jinping are set to meet Saturday evening for a formal dinner on the sidelines of the G20 meeting in Argentina. It is their only scheduled meeting before the end of the year.White House economic adviser Larry Kudlow on Tuesday dangled the possibility?of a "breakthrough" at the dinner. But Trump escalated tensions earlier in the week, when he repeated a threat to put tariffs on the remaining Chinese goods if a deal can't be reached.The Trump administration argues that China is engaging in unfair trade practices, including intellectual property theft and forced technology transfers. But the Chinese say Trump's unilateral tariffs are bullying.American businesses and lawmakers on both sides of the aisle agree that the China trade issues should be addressed — but not everyone believes that tariffs are the right way. Some manufacturers and retailers say the duties could lead to job losses and higher prices for consumers."It would be hard to argue that (China) has behaved fairly in its trade practices," said Florida Democratic Rep. Stephanie Murphy this week at an S&P Global event in New York."But I think doing it in a multilateral way would have been a better approach," she said.Trump has also imposed tariffs on foreign steel and aluminum this year, in the interest of national security. US steel producers have welcomed the taxes, as they've seen prices for their own products go up. Steel Dynamics, an American producer, announced this week that they would be building a new steel mill in the southwest region of the country, creating 600 new jobs."Steel jobs are coming back to America, just like I predicted," Trump tweeted Wednesday.But American manufacturers that use steel, including automakers, have argued that the tariffs have made the cost of domestic production more expensive. 4055

QUEENS, NY — The childhood home of President Donald Trump in Queens, New York is reportedly for sale. A real estate agency is asking Trump supporters to donate to help purchase the five-bedroom, five-bathroom home, to show their “love.”“Love Trump? Thank President Trump by contributing to this campaign to buy his childhood home in his honor!” a GoFundMe page reads.The Tudor-style home along Wareham Place failed to sell at auction last year, and is listed for sale. Paramount Realty USA started the GoFundMe page to raise donations, with a goal of million. As of Monday morning, they had around ,500.“We are raising funds to buy President Trump's childhood home for him, or a charity of his choosing, as a token of appreciation. What happens to the historic property is up to him!” the group states in the description of their fundraiser.The group lists possible uses for Trump’s childhood home, including as a presidential library, national historic site, trophy property or house of worship.In September 2016, President Trump told tv host Jimmy Fallon “that’s really sad looking at that, I want to buy it, I want to buy it,” when Fallon informed the president his childhood home was for sale and showed images of it.According to Paramount Realty, the home sold in 2017 for about .14 million. For a brief time, Airbnb listed the home as available to rent for roughly 0/night after the 2017 sale. Online home listing sites have details of the home, now for sale again, including images of the interior of the home with what appears to be a cut-out of President Trump. The home appears to be listed for .9 million.Trump lived at the home from birth to around age 4, when his family moved to another home adjacent to the Wareham Place property. 1765

Prince Andrew's legal team has told CNN that they will not comment on the arrest of Ghislaine Maxwell, a day after an acting U.S. Attorney urged him to come forward with information about the case.On Thursday, Maxwell was charged with four counts relating to her alleged involvement in recruiting and trafficking underage girls for Epstein and two counts of perjury. Epstein himself was arrested and charged with trafficking in 2019, but weeks later was found dead in his jail cell.In announcing the charges against Maxwell on Thursday, Audrey Strauss — the acting U.S. attorney for the Southern District of New York — urged anyone with information about the case to come forward, particularly Prince Andrew."We would welcome Prince Andrew coming in to talk with us. We would like to have the benefit of his statement," Strauss said in response to a question about Prince Andrew's involvement in the case.Prince Andrew was a known associate of Epstein and even stayed at his New York apartment in 2010 — two years after Epstein pleaded guilty to sex crimes. Prince Andrew also appears in a photograph with Maxwell and a girl who has since claimed Prince Andrew and Epstein abused her.The Duke of York has strongly denied any wrongdoing in his connection to the case.Sources also told CNN that Prince Andrew's legal team says it's "bewildered" and claimed the team has communicated with the Justice Department twice in the last month. Prince Andrew's representatives claim they never received a response from the Justice Department.British Prime Minister Boris Johnson also refused to comment on the matter Friday, saying he cannot be expected to comment on matters relating to the Royal Family."It's just not the tradition; it's not what we do," Johnson said. 1767

President-elect Joe Biden still has two more months before he is sworn in, and while many Republicans are finding it difficult to accept his win, Biden is meeting with key Democrats in hopes of having a deal in place for an economic stimulus plan. Biden has spoken with the top two Democrats in Congress — but not their Republican counterparts yet.Biden’s transition team announced Thursday that he spoke by phone with House Speaker Nancy Pelosi and Senate Democratic leader Chuck Schumer, thanking them for their congratulations and expressing “his commitment to uniting the country after a hard-fought campaign.”The three spoke about “intensifying” the country’s coronavirus response and coping with the economic fallout the pandemic has inflected. They also discussed the “urgent need” to use the lame duck congressional session to approve bills on slowing the spread of COVID-19, as well as economic relief for “working families and small businesses, support for state and local governments trying to keep front-line workers on the payroll,” expanded unemployment insurance and expanded access to affordable health care.Biden said Tuesday that he had not spoken to Senate Majority Leader Mitch McConnell, though the two have been friends for years.But there is still optimism this week among some on Capitol Hill a deal on economic stimulus can be approved during the lame duck session. "The need is too urgent. We need to do it now. Not wait. Families are going to be coming together, even though in smaller groups for Thanksgiving. They should have the assurance of another stimulus payment by Thanksgiving. It's doable," said Sen. Richard Blumenthal, D-Connecticut. 1680