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WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.

QINGDAO, Shandong, Dec. 26 (Xinhua) -- China's largest rail vehicle maker, CSR Corp. Ltd, over the weekend launched its first test train that features speeds reaching up to 500 km per hour.The six-car train with a fairshaped head is the newest in the CRH series. It has a maximum tractive power of 22,800 kilowatts, compared with 9,600 kilowatts for the CRH380 trains currently in service on the Beijing-Shanghai High-Speed Railway, which hold the world speed record of 300 km per hour.The grey-color train carrying testing and data processing facilities was designed and produced by CSR Sifang Locomotive & Rolling Stock Co., Ltd (Sifang Locomotive), a CSR subsidiary based in the coastal city of Qingdao in eastern Shandong province.Ding Sansan, the company's chief technician, said the concept of the the super-speed train design was inspired by China's ancient sword. The bodywork uses plastic materials reinforced with carbon fiber.Shen Zhiyun, a locomotive expert and academician with both the Chinese academies of sciences and engineering, said the testing of the super-speed train with speeds of up to 500 km per hour will provide useful reference for current high-speed railway operations.

BEIJING, Dec. 23 (Xinhua) -- The personal information of more than 6 million Internet users on CSDN, or China Software Developer Network, the country's largest programmers' website, was leaked by hackers, raising concerns about web security and triggering widespread panic.The leak was first exposed by China's leading anti-virus software provider, Beijing-based Qihoo 360, on Wednesday. The company said the leak included user IDs, passwords and e-mail addresses in clear text.The hacking case escalated on Thursday after the personal details of subscribers to more websites, including popular online gaming and social networking sites, were leaked.Online media reports said the personal data of up to 50 million Internet users has been leaked so far, but the number could not be independently verified.In response, the National Computer Network Emergency Response Technical Team/Coordination Center of China (CNCERT/CC) issued a statement Thursday, saying the CSDN's user data bank that leaked on the Internet was created before April 2009 and the passwords were stored in clear text, but the passwords had been encrypted after the data bank was upgraded in April 2009."Therefore, similar security problems have not been found in the newest user data bank," the statement said.Technical experts are investigating how many websites and users were actually involved in the hacking case, said Zhou Yonglin, director of the CNCERT/CC Operating Department."False information and exaggerations cannot be ruled out," he said.Nevertheless, CNCERT/CC has ordered CSDN to take immediate action in repairing the system hazards and providing users with timely security solutions.Computer security experts at Qihoo 360 believe the leak has spread to other websites."Many Internet users have registered the same passwords for their e-mail, microblog, online gaming and online payment accounts, so, if the server of one of the websites is hacked, their accounts and passwords on other websites would also be stolen," said Qihoo 360's Dr. Shi Xiaohong.Police authorities in Beijing told Xinhua on Friday that an investigation has been launched.WEB SECURITY IN QUESTIONDisgruntled Internet users in China rushed to change their passwords after the leak occurred, the largest of its kind in the history of China's Internet development."It is very annoying. I had to spend almost an hour changing the passwords of all my online accounts, especially those for payment accounts," said Li Xing, a white-collar worker at a technical company in Beijing.

NANCHANG, Oct. 1 (Xinhua) -- A copper sword dating back more than 2,200 years has been discovered in east China's Jiangxi Province, local archaeologists said.The design and shape of the sword indicate that it was forged during the Warring States Period (475 BC - 221 BC), according to Li Guoli, curator of the Nanchang Museum, where the sword is currently being stored.Despite having little aesthetic or scientific value due to a lack of decor or inscriptions, the sword still offers insights into the type of military equipment used during the period, Li said.The identity of the sword's original owner and the precise location where the sword was forged and used are still unknown, Li said.The sword was discovered by a laborer surnamed Xiong in Jiangxi's capital of Nanchang. Xiong found the sword while sorting and cleaning stones that had been dredged up from a riverbank.An argument between Xiong and another worker who was trying to claim the sword aroused attention from the local law enforcement, who then convinced Xiong to turn the sword over to archaeological authorities.

BEIJING, Nov. 25 (Xinhua) -- The BRICS members should make joint efforts to help ease tension in the Middle East and support the region's countries in carrying out political transition and social reconstruction on their own, Chinese Foreign Ministry spokesman Liu Weimin said Friday.Liu made the remarks at a daily press briefing, after Vice Foreign Minister Zhai Jun attended a deputy foreign ministers' conference of the BRICS in the Russian capital of Moscow on Thursday.The BRICS countries' enhanced communication and coordination, joint maintenance of the basic principles of international law, and opposition to foreign armed interference in the region are in line with the common interests of Middle East countries and the international community, Liu said."China will make concerted efforts with the international society, including BRICS members, to make constructive contribution to the Middle East's peace, stability and development," Liu said.The spokesman quoted Zhai Jun as saying at the Moscow conference that the Middle East's situation has a significant impact on international politics, economy and security in addition to the impact on the political and social situations in the region.It conforms with the common interests of the region's countries and the international community for the Middle East to be politically open and inclusive, independent in foreign policy, sustainable in economic development, and peaceful and stable in security matters, Zhai was quoted as saying.Liu Weimin said a joint communique was issued at the Moscow conference. The communique called on various parties to respect the state sovereignty and territorial integrity of the Middle East countries, have extensive dialogues by peaceful means, and make active efforts to seek solutions to the crisis.The BRICS members oppose the interference in the Middle East countries' internal affairs by foreign forces, advocate the positive role of the United Nations Security Council, and urge various parties to strictly observe the authorization of the UN Security Council, according to Liu.BRICS is an acronym for Brazil, Russia, India, China and South Africa.

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