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The White House physician assigned to Vice President Mike Pence, Jennifer Pena, has resigned, his office told CNN in a statement Friday. Pena worked in the White House medical unit."The vice president's office was informed today by the White House Medical Unit of the resignation. Physicians assigned to the vice president report to the White House Medical Unit and thus any resignation would go entirely through the Medical Unit, not the vice president's office," Alyssa Farah, Pence's press secretary, said in a statement to CNN.This comes after CNN reported Tuesday that a Pence doctor privately raised alarms within the White House last fall that President Donald Trump's doctor Ronny Jackson may have violated federal privacy protections for a key patient -- Pence's wife, Karen -- and intimidated the vice president's doctor during angry confrontations over the episode.  890

The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The Trump administration has finalized a regulation that overturns Obama-era protections for transgender people against sex discrimination in health care. Friday's action is certain to be challenged in court by LGBTQ groups and others.The policy shift, long-sought by the president’s religious and socially conservative supporters, defines gender as a person’s biological sex. The Obama regulation defined gender as a person’s internal sense of being male, female, neither, or a combination.The Trump administration said that the new rules come with a .9 billion budget reduction over the course of five years. The costs are associated with enforcement efforts. “HHS respects the dignity of every human being, and as we have shown in our response to the pandemic, we vigorously protect and enforce the civil rights of all to the fullest extent permitted by our laws as passed by Congress. We are unwavering in our commitment to enforcing civil rights in healthcare,” Roger Severino, Director of the Office for Civil Rights at HHS.The Human Rights Campaign already announced it will sue the Trump Administration to stop the move.“We cannot and will not allow Donald Trump to continue attacking us. Today, the Human Rights Campaign is announcing plans to sue the Trump administration for exceeding their legal authority and attempting to remove basic health care protections from vulnerable communities including LGBTQ people. And, to add insult to injury, the administration finalized this rule on the anniversary of the Pulse shooting, where a gunman killed 49 people in an LGBTQ nightclub,” said HRC President Alphonso David. “LGBTQ people get sick. LGBTQ people need health care. LGBTQ people should not live in fear that they cannot get the care they need simply because of who they are. It is clear that this administration does not believe that LGBTQ people, or other marginalized communities, deserve equality under the law. 1940

The Salt Lake Tribune reported late Monday night that at least one person has died in a 'shots fired' incident on the University of Utah's campus. According to the university, it asked those on campus to "shelter in place" Monday night as authorities looked for the gunman, and other possible victims. Traffic was reportedly blocked off, and mass transit was shut down in the immediate vicinity of the shooting. The suspect is said to be 24-year-old Austin J. Boutain, who was wearing a coat, jeans and beanie, with a teardrop tattoo on his face. The university added that he may have been driving a forest green pick-up truck with Colorado plates.As of early Tuesday morning, he was still on the loose, and considered dangerous. 767

The woman who opened fire at YouTube headquarters Tuesday practiced shooting at a gun range hours before the attack, police said. She then took her 9 mm Smith & Wesson handgun to the Silicon Valley campus and shot three people she apparently didn't know, San Bruno police Chief Ed Barberini said.All this because Nasim Najafi Aghdam was upset with YouTube's practices and policies."We know she was upset with YouTube, and now we've determined that was the motive," Barberini said.Aghdam shot and wounded three people before killing herself. Two of her victims have been released from the hospital, and one remains in serious condition.Barberini said the shooter did not have a link or relationship with the three people she shot.  747

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