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Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

Doc Rivers confirmed he will not be back as the NBA Los Angeles Clippers’ head coach following a stunning loss in the Western Conference semifinals earlier this month.Rivers’ Clippers, bolstered by the addition of Kawhi Leonard this season, was set on a collision course with the Clippers’ in-arena rival Los Angeles Lakers for the Western Conference title. The Denver Nuggets stood in the Clippers’ way of playing the Lakers. The Clippers blew a 3-1 series lead by losing to Denver three consecutive games.The Clippers finished the regular season in second place, behind the Lakers, in the Western Conference standings.River released the following statement:“Thank you Clipper Nation for allowing me to be your coach and for all your support in helping make this a winning franchise. When I took this job, my goals were to make this a winning basketball program, a free agent destination, and bring a championship to this organization.“While I was able to accomplish most of my goals, I won't be able to see them all through. Though it was a disappointing ending to our season, you are right there and I know what this team is capable of accomplishing with your support. Thank you to all the players, coaches, and staff for helping us get here. Most importantly, thank you to the fans. We went through a lot, and I am grateful for my time here.”Rivers is seventh all time in playoff wins with 91 and 11th all time in regular season victories with 941. In his seven seasons with the Clippers, Rivers’ squads made the playoffs six times, but failed to advance to the conference finals.Before coaching in Los Angeles, Rivers coached in Orlando and Boston. Rivers steered the Celtics to an NBA title in 2008. 1713

Dr. Christina Blasey Ford has been nominated for a University of North Carolina at Chapel Hill Distinguished Alumna Award for "speaking truth to power" by going public with sexual assault allegations against then-Supreme Court nominee Brett Kavanaugh."What Dr. Blasey Ford did on September 27, 2018 was something that was extraordinary in how ordinary it was: she told the truth about a sexual assault she experienced when she was fifteen years old at the hands of Judge Brett Kavanaugh," wrote UNC English professor Dr. Jennifer Ho in the letter nominating Ford, speaking about the California professor's testimony last month in front of the Senate Judiciary Committee.Ford, who graduated from UNC with a bachelor's degree in psychology in 1988, accused Kavanaugh of sexually assaulting her at a house party when the two were in high school. Kavanaugh has denied all allegations against him.Both Ford and Kavanaugh testified before the committee, prompting a weeklong FBI investigation and hundreds of activist protesters on Capitol Hillbefore the Senate confirmed Kavanaugh by?a 50-48 vote Saturday afternoon."Dr. Blasey Ford giving her testimony, speaking truth to power, was an inspiration for so many of us," Ho wrote. "Her accomplishment is to be an alumna of integrity, who despite great personal cost to herself and her family told her story of her sexual assault and emboldened others to also find the courage to speak out against injustice."Comments from Ho on the letter indicated that after signatures on the letter were maliciously deleted, signatures supporting the letter could be submitted through a secure form until midnight on October 13.According to the UNC awards web page, nominees must have made "an outstanding contribution to humanity in any walk of life" and must be nominated by October 15. 1880

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said on Tuesday that he will celebrate his 80th birthday virtually through a Zoom call.Fauci turns 80 on Thursday, and has been working long hours as the federal government’s leading infectious disease expert amid the coronavirus pandemic. In an interview with CNN’s Wolf Blitzer, Fauci said he normally spends his birthday with his daughters.With the coronavirus pandemic still spreading through the US, Fauci will only be spending the milestone in person with his wife.Fauci’s birthday comes one day before Christmas. He is following the type of advice he has been giving to Americans amid the holidays. The US is averaging more than 2,500 coronavirus-related deaths and is still battling a surge spurred by Thanksgiving gatherings.“I am going to practice what I am preaching to my fellow Americans in this country,” Fauci told Blitzer. “I am going to do something that is quite modified from what I had done traditionally. I am going to have a quiet dinner in my home with my wife. I would love to have my three daughters who are on different parts of the country, different states that would have to fly in for the most part. We are going to do a Zoom together. We are going to be talking to each other and toasting each other.”Fauci cautioned that people should avoid traveling during the holidays.“This type of travel is risky,” Fauci said. “Particularly if people start congregating, when they get to their destination in larger crowds in indoor settings, I'm afraid that if in fact we see this happen, we will have a surge that's superimposed upon the difficult situation we are already. And so it could be a very difficult January coming up. If these things happen.”In the District of Columbia, Thursday has been proclaimed “Dr. Anthony S. Fauci Day” by mayor Muriel Bowser.“We are incredibly proud to count Dr. Fauci among the many DC residents who are sacrificing so much to keep our communities healthy and safe,” Bowser said. 2036

During a town hall event on ABC on Tuesday night, President Donald Trump defended his administration's response to the COVID-19 pandemic and attempted to distance himself from his leaked admission that he "downplayed" the pandemic.During the event, hosted by George Stephanopoulos, Trump was repeatedly asked about the comments he made to journalist Bob Woodward in March that leaked earlier this month in which he said he wanted to "downplay" the pandemics so as "not to cause a panic."When Stephanopolous brought up the comments, Trump explained that he was simply saying he didn't "want to drive the nation into a panic.""I'm a cheerleader for this nation. I'm the one who closed up our country. I closed up the country long before any of the experts thought I should," Trump said.One study by Columbia University estimates that 36,000 lives could have been saved if the U.S. had locked down and adopted social distancing measures just one week sooner.When asked directly by an audience member about his comments to Woodward, Trump claimed his actions proved he "up-played" the pandemic."Well, I didn't downplay it. In many ways, I actually up-played it in terms of action. My action was very strong," Trump said.Trump pointed to travel restrictions he imposed to China on Feb. 2 and on Europe on March 13 as evidence that he "up-played" his response to the virus. Both restrictions still allowed some travel from the regions to enter the U.S.The President also questioned the effectiveness of masks during the event. While Trump said that he wears masks "in hospitals" and in other situations, he added that "a lot of people think the masks are not good."When asked to clarify, Trump identified "waiters" and restaurant servers in particular, adding that a server "the other day" had been fidgeting with a mask while touching his plate."That can't be good," Trump said.In a press briefing on Wednesday, Press Secretary Kayleigh McEnany said that Trump "agreed with Dr. Fauci" and was pointing out the "unintended consequences" of wearing masks and highlighting proper mask-wearing techniques.The President also explained his skepticism by citing recommendations from the CDC and Dr. Anthony Fauci from March against wearing masks. At the time, health officials did not recommend the use of masks over a fear of nationwide shortage. Since April, the CDC has recommended that all Americans wear masks when in situations where social distancing is difficult, and Fauci has admitted that "mixed messaging" on mask use by the government put the U.S. behind in its response to the virus.Trump also criticized Democratic presidential candidate Joe Biden for not instituting a nationwide mask mandate, despite the fact that Biden does not currently hold public office."Like Joe Biden, they said they were going to do a national mandate on masks...he didn't do it. He never did it," Trump said.Trump closed the segment on COVID-19 by claiming without evidence that the virus would "go away without a vaccine." Trump said that the U.S. "over a period of time" would develop a cure that would be "herd developed," even without a vaccine.Health officials say that the U.S. will develop "herd immunity" when 70% of the country develops COVID-19 antibodies, whether through contraction or vaccination. Because the virus is so novel, it's unclear how long immunity will last or if the immunity or if COVID-19 mutations will limit immunity.During Wednesday's briefing, McEnany clarified that "herd immunity" was not a COVID-19 containment strategy considered by the White House. 3574

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