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LONDON (AP) — AstraZeneca and Oxford University have acknowledged a manufacturing error that is raising questions about preliminary results of their COVID-19 vaccine.A statement Wednesday describing the error came days after the company and the university described the shots as “highly effective” and made no mention of why some participants didn’t receive as much vaccine as expected.In a surprise, the group of volunteers that got half a dose in the first of their two shots seemed to be better protected than the volunteers who got full doses. The low-dose group was smaller and younger, however, which could have skewed the results, experts say.In a statement obtained by CNN, Oxford elaborated further, saying that a “difference in the manufacturing process” had led to the error.The university said that it discussed the problem with regulators, agreed to complete the late stage trial with two groups, and the problem has since been corrected. 959

LOS ANGELES (CNS) - As the use of legal and illegal fireworks around the Los Angeles area exploded this Fourth of July, fire departments saw a sharp increase in the number of calls for service, authorities said Sunday.It was the second-busiest day ever in calls for service from the Los Angeles County Fire Department, according to Dispatch Supervisor Imy McBride.The dispatchers usually field 1,000 calls on an average day, McBride said. On July 4th, they handled more than 1,600 calls, including tree, brush and roof fires.Los Angeles City firefighters responded to 1,770 calls for service from 3 a.m. July 4 to 3 a.m. Sunday, spokesman Nicholas Prange said. The department averaged 1,368 calls per day during the same period in 2019, he said.The July 4 fires included one that burned trees and the roof of a garden-style apartment building on Wilbur Avenue in Northridge with five people suffering smoke inhalation and 50 residents being displaced, Prange said.There was also a three-acre brush fire in Shadow Hills and a fire that spread from palm trees to the roof of an apartment building in Reseda.McBride and Prange said it was unclear whether the fires were related to the increase use of fireworks. 1216

LOS ANGELES (CNS) - Four people were wounded, one fatally, when gunfire erupted Tuesday morning at a large party taking place at a mansion north of Beverly Hills where police had earlier responded to multiple calls of disturbing the peace.Firefighters and paramedics sent to the 13200 block of Mulholland Drive about 12:45 a.m. located three adults who had been wounded, and they were treated at the scene, then taken to a hospital, according to Nicholas Prange of the Los Angeles Fire Department. A fourth person was found nearby with an injury to his wrist, Prange said, adding the victim's injury was not caused by gunfire.One shooting victim was hospitalized in grave condition and the other two were hospitalized in critical condition, Prange said.A woman about 35 years of age died at a hospital, said Los Angeles Police Department Lt. Chris Ramirez. Information was not immediately available on her identity.Ramirez said the other two shooting victims found at the scene were males, and they were displaying stable vital signs Tuesday morning.A woman who also had been shot went to a hospital in a private vehicle, and was in stable condition, Ramirez said.Ramirez said the crime apparently was gang-related, and no arrests have been reported. No suspect information was immediately available.Ramirez said the shooting was being investigated by detectives from the LAPD West Bureau Homicide office, and he urged anyone with information on the crime to call 213-382-9470.The house had been rented for the party, according to reports from the scene.A video posted to social media captured the sounds of the gunfire, at least six shots initially fired, followed by at least eight more. People attending the party continued on as if nothing had occurred following the gunfire, the video showed. About two minutes later, a hail of gunfire can be heard and people begin screaming and running and trying to find safe places to hide. The video also contained blurry images of what appeared to be two gunshot victims.The Los Angeles Police Department received at least five calls from residents who reported instances of disturbing the peace in the neighborhood beginning about 6:30 p.m. Monday. Responding officers found a large party taking place at a three-story home with about 200 people attending, according to the LAPD.Officers enforced traffic and parking violations, but did not enforce the county's health order banning large gatherings, the department said. Video from NBC4 showed vehicles being ticketed.The organizer of the party, identified by NBC4 only as "Kenny," told the station the party was for his friends and masks were made available to guests, who also had to undergo a temperature check before being allowed inside.No party attendees could be seen wearing masks in video shot by multiple broadcast outlets.A food truck was on site and multiple high-end vehicle, including Lamborghinis and a Rolls Royce, could be seen on the video posted to social media.The party is the second large-scale gathering held amid the coronavirus pandemic in the L.A. area, in spite of public health restrictions barring parties.On Friday night, dozens of people were seen attending a party -- again, mostly without masks or physical distancing -- at the Sassafras Saloon in Hollywood, a gathering that was alleged to have been attended by local law enforcement members. A person familiar with the gathering told the Los Angeles Times the party was planned for members of the Los Angeles County Sheriff's Department, but the agency has denied any involvement in the event and insisted that people seen in online video from the event do not work for the department.The Los Angeles Police Department issued a statement Monday saying it was aware of the gathering and was working to determine if any LAPD employees attended.Los Angeles County public health director Barbara Ferrer said Monday the state Department of Alcohol and Beverage Control was investigating the party, along with the county. She said county health inspectors went to the Vine Street bar Saturday and were told the venue has been closed but only opened for the Friday night private party. 4167

LOS ANGELES - A representative for Mel Gibson says the actor spent a week in a Los Angeles hospital in April after testing positive for COVID-19. The 64-year-old actor and director has completely recovered, is doing “great'' and has since tested negative “numerous times.” Gibson is the latest in a long string of high profile figures to go public with coronavirus diagnoses and recoveries including Tom Hanks, Rita Wilson, George Stephanopoulos and the singer Pink. The U.S. has more than 4 million known cases of the coronavirus and more than 140,000 deaths. 568

LONDON (AP) — The U.K. military seized control of an oil tanker that dropped anchor in the English Channel after reporting it had seven stowaways on board who had become violent. Defense Secretary Ben Wallace and Home Secretary Priti Patel authorized the action in response to a police request. Initial reports confirm the crew was safe. The incident began about 10 a.m. on the Libyan-registered tanker Nave Andromeda. Authorities imposed a three-mile exclusion zone around the vessel. A retired Royal Navy rear admiral told The Associated Press he suspects the stowaways grew violent as the tanker neared port, and the crew retreated to a secure area known as “the citadel” to retain control of the vessel. 715

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