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Potential accuracy issues with a widely used coronavirus test could lead to false results for patients, U.S. health officials warned.The Food and Drug Administration issued the alert Monday to doctors and laboratory technicians using Thermo Fisher’s TaqPath genetic test. Regulators said issues related to laboratory equipment and software used to run the test could lead to inaccuracies. The agency advised technicians to follow updated instructions and software developed by the company to ensure accurate results.The warning comes nearly a month after Connecticut public health officials first reported that at least 90 people had received false positive results for the coronavirus. Most of those receiving the false results were residents of nursing homes or assisted living facilities.A spokeswoman for Thermo Fisher said the company was working with FDA “to make sure that laboratory personnel understand the need for strict adherence to the instructions for use.” She added that company data shows most users “follow our workflow properly and obtain accurate results.”The FDA said one possible problem was related to the incorrect use of equipment that rapidly spins samples in preparation for processing. The agency’s letter tells lab workers to follow new instructions developed by the company for this step.A second issue relates to the software used on Thermo Fisher’s testing platform. FDA said labs must upgrade the software to a new version.Dr. Albert Ko of Yale’s School of Public Health said the potential accuracy problems have “pretty serious implications” given that Thermo Fisher’s test is used widely both in the U.S. and around the world to screen for coronavirus.The FDA statement did not provide any details on how many test results may have been affected by the problem.Lab tests are the backbone of U.S. screening for coronavirus, accounting for more than half of the roughly 750,000 tests developed daily. The tests look for traces of coronavirus’ genetic material in nasal swabs taken from patients.Thermo Fisher’s test was granted emergency use by the FDA in mid-March. The test runs on a large, automated machine used in hospital, government and commercial labs to look for diseases such as HIV, hepatitis and flu.The FDA has used its emergency powers to OK more than 200 tests for coronavirus since February. No test is perfect and all are expected to give at least a small percentage of false negatives and false positives.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2656
President Donald Trump described Oprah Winfrey as "very insecure" and accused her of "biased and slanted" after an interview on CBS's "60 Minutes" that addressed his presidency.Oprah hosted a group discussion with 14 voters who had appeared on the show in fall 2017 -- half who had voted for Trump and half who had not.The discussion looked at whether the the pro-Trump panelists still backed the President, his alleged "s***hole countries" comments, the worldview of the US under his leadership, questions around Trump's stability and fitness for office, and accusations of inappropriate sexual behavior.""Just watched a very insecure Oprah Winfrey, who at one point I knew very well, interview a panel of people on 60 Minutes. The questions were biased and slanted, the facts incorrect. Hope Oprah runs so she can be exposed and defeated just like all of the others!" Trump tweeted after the show was broadcast. Just watched a very insecure Oprah Winfrey, who at one point I knew very well, interview a panel of people on 60 Minutes. The questions were biased and slanted, the facts incorrect. Hope Oprah runs so she can be exposed and defeated just like all of the others!— Donald J. Trump (@realDonaldTrump) February 19, 2018 1242
President Donald Trump again called for an end to the filibuster and said there will be no deal with Democrats on the Deferred Action for Childhood Arrivals, also known as DACA."Border Patrol Agents are not allowed to properly do their job at the Border because of ridiculous liberal (Democrat) laws like Catch & Release. Getting more dangerous. 'Caravans' coming. Republicans must go to Nuclear Option to pass tough laws NOW. NO MORE DACA DEAL," Trump tweeted Sunday morning.This isn't the first time Trump has called for a change to Senate rules by invoking the "nuclear option," which would permit a simple majority to move forward on a measure. Last May, he called for?Congress to move to a simple majority to pass health care and tax reform bills. 779
President Donald Trump bemoaned a decision not to investigate Hillary Clinton after the 2016 presidential election, decrying a "rigged system" that still doesn't have the "right people" in place to fix it, during a freewheeling speech to Republican donors in Florida on Saturday.In the closed-door remarks, a recording of which was obtained by CNN, Trump also praised China's President Xi Jinping for recently consolidating power and extending his potential tenure, musing he wouldn't mind making such a maneuver himself."He's now president for life. President for life. And he's great," Trump said. "And look, he was able to do that. I think it's great. Maybe we'll give that a shot some day."The remarks, delivered inside the ballroom at his Mar-a-Lago estate during a lunch and fundraiser, were upbeat, lengthy, and peppered with jokes and laughter. But Trump's words reflected his deeply felt resentment that his actions during the 2016 campaign remain under scrutiny while those of his former rival, Hillary Clinton, do not."I'm telling you, it's a rigged system folks," Trump said. "I've been saying that for a long time. It's a rigged system. And we don't have the right people in there yet. We have a lot of great people, but certain things, we don't have the right people."Trump has repeatedly said that his attorney general, Jeff Sessions, should launch investigations into Clinton, and has continued to lambast Sessions on Twitter for not taking what he views as appropriate steps to probe Clinton's actions involving her private email server.The stewing anger with Sessions has soured Trump's mood over the past week, including on Wednesday evening, when he fumed inside the White House over his attorney general's decision to release a statement defending himself after Trump chastised his approach to an investigation into alleged surveillance abuses as "DISGRACEFUL" on Twitter.The episode was just one irritant in a long series of upsetting moments for Trump this week. Morale at the White House has dropped to new lows, and Trump himself has seethed at the negative headlines.On Saturday, among donors gathered in the grand ballroom named for himself at Mar-a-Lago, Trump pondered the happiness of his former rival, wondering aloud whether she was enjoying life after the campaign."Is Hillary a happy person? Do you think she's happy?" he said. "When she goes home at night, does she say, 'What a great life?' I don't think so. You never know. I hope she's happy."Elsewhere in his remarks, Trump went after former President George W. Bush for his decision to invade Iraq after faulty intelligence indicated the country had weapons of mass destruction."Here we are, like the dummies of the world, because we had bad politicians running our country for a long time," he said.Trump called the Iraq invasion "the single worst decision ever made" and said it amounted to "throwing a big fat brick into a hornet's nest.""That was Bush. Another real genius. That was Bush," Trump said sarcastically. "That turned out to be wonderful intelligence. Great intelligence agency there."Trump has previously cited the WMD failure to go after US intelligence agencies, bringing up the error as a reason to doubt the same agencies conclusions' that Russia meddled in the 2016 election.The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 3390
Powerful winds are expected to sweep through California on Sunday, exacerbating three major fires that have ravaged the state from both ends for several days.The Camp Fire -- the most destructive fire in state history and the third-deadliest -- has killed at least 23 people and 110 are missing. Hundreds of thousands of residents have been displaced and thousands of homes and structures have been destroyed.Saturday saw a brief reprieve in the fierce winds fueling the fires, and firefighters hoped to use the break to their advantage.PHOTOS: 3 wildfires rage in CaliforniaBut on Sunday a Cal Fire unit chief warned that "it's not over yet." 651