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SAN DIEGO (KGTV) — Researchers at the University of California, San Francisco are working on a spray designed to block the novel coronavirus from hijacking cells in the body, like a biological mask or internal personal protective equipment.They’re doing it by borrowing a defense mechanism from an unlikely source: llamas.The team, led by UCSF graduate student Michael Schoof, engineered a synthetic molecule based on one found in a llama’s immune system that acts like an antibody but is one-tenth the size.Human antibody treatments, known as convalescent plasma, require a transfusion in a hospital setting. But this smaller molecule, called a nanobody, can be easily self-administered via an inhaler or nasal spray and rapidly manufactured using yeast, Schoof said.The scientists named their product AeroNabs. They say it could be an inexpensive intervention for treating and preventing COVID-19 while the world waits for a vaccine.“We don't know how effective vaccines will be. We don't know how long it will take to rapidly deploy them, so we envision this product as hopefully a bridge until there is widespread, effective vaccination,” Schoof said.Once a vaccine is available, AeroNabs could offer protection for individuals who are unable to be inoculated for health reasons, he said, or an early treatment option.The team is in talks with commercial partners and hopes to begin clinical trials soon.In the 1980s, Belgian scientists discovered that about half of the antibodies in camels, llamas and alpacas are shaped differently than the antibodies found in other mammals, including humans. Researchers later learned they could use a fragment of these oddly shaped camelid antibodies to bind to antigens.Those fragments are called nanobodies.Currently, there is only one FDA-approved drug that uses nanobodies. Caplacizumab was approved last year to treat a rare blood disorder.The team at UCSF sifted through billions of nanobodies to find one that binded best to the spike proteins on the coronavirus, then engineered it to stick even better.The coronavirus uses its spikes to enter cells and replicate; the spikes are essentially the pathogen’s key into the body. By coating the spikes with nanobodies or antibodies, the viral key no longer fits into the body’s receptors and the virus can’t get in.“This works in the lab. It needs to be translated into the clinic,” said Schoof.The team at UCSF still needs to figure out the best delivery method, whether it is a nebulizer, an inhaler or a nasal spray. 2524

SAN DIEGO (KGTV) -- San Diego Police are asking for the public’s help finding a man who went missing early in the day Wednesday. According to police, 77-year-old David McArthur left his home on the 7900 block of Wing Span Drive around 10 a.m. to work on his boat at The Southwestern Yacht Club. He was last seen walking toward his vehicle in the parking lot of the yacht club, according to a family friend. McArthur was diagnosed with Alzheimer’s six years ago. McArthur is described as a white man, 77-years-old who is bald with grey hair on the sides and a thin build. Police say he also wears a yellow metal wedding ring and black band digital watch on his left wrist. McArthur is from New Zealand and speaks with a slight accent. He drives a 20907 Infinity G35 two-door coupe with California license plate 5XMW652. Anyone with information is asked to call the San Diego Police Department at 619-531-2000. 917

SAN DIEGO (KGTV) - San Diego Police identified Tuesday the officer involved in a shooting in Little Italy Saturday.Several witnesses flagged down a patrol car driving at 1300 India Street about 6:45 p.m. to let the officer know about a man who was not wearing a shirt and acting belligerently.The SDPD report indicated Officer Anthony Bueno found the man, Brent Zadina, on the hood of a car, yelling at the driver.RELATED: Officer Bueno has history of conflictsZadina appeared to be drunk or under the influence of drugs, police said.Officer Bueno tried to arrest Zadina but he resisted and the officer used his taser, according to the report. Zadina continued to struggle and the officer feared for his life, said the SDPD.Officer Bueno fired one round but missed Zadina. No one was injured.Additional officers arrived and handcuffed Zadina, who was taken to the hospital for observation.San Diego Police said Zadina remains at the hospital and will be booked into jail when he is released.Officer Bueno is a 19-year veteran of the police force.Anyone with information is asked to call the San Diego Police Department at 619-531-2293. 1148

SAN DIEGO (KGTV) - Rent isn't the only thing in San Diego on the rise - so are the costs and fees associated with it. A recent study from HotPads, a Zillow-owned site, says San Diegans can pay ,270 per year in overlooked costs and fees that come with moving. The includes security and pet deposits, pet rent and parking. The biggest chunk comes from the security deposit, which is typically one month's rent. In all, it works out to an additional 6 per month. "As rent prices continue to rise and rent affordability remains a concern, it is important for renters to consider all their potential expenses before planning a move," said Joshua Clark, economist at HotPads. RELATED: Making It in San Diego: Ways to save on your rental homeApril Steingrebe, who owns New West Property Management, said it's vital to read your lease thoroughly before renting a place, looking for any additional responsibilities. "There's all kinds of things they might charge you for at move-in, so you want to be sure to check before you sign anything," she said. Steingrebe focuses largely on downtown, renting out privately owned condos. She says some buildings even require tenants hire move-in coordinators to make sure things go smoothly and not disturb other residents. RELATED: San Diego's top neighborhoods to get more rental space for the moneySteingrebe said in addition to security deposits and fees, downtown condo living comes with living under a homeowners association's rules. Renters don't pay the HOA directly, but landlord's can pass along any sort of fines or violations they commit. "Unauthorized moves, these buildings downtown, you can't just walk in with your couch, you have to schedule it," Steingrebe said, adding dumping trash inappropriately can also lead to fines. The biggest financial issues that arise for renters come at the end of a lease, when it comes to getting a security deposit refunded, Steingrebe said. She said the best defense is to document with photos and text any damage or issues that occur throughout the year, starting with an initial move-in inspection. RELATED: Making It in San Diego: Sailor gets proactive to find housing"A lot of times if you have that documentation and you show your landlord, they go, 'okay, we're not going to mess with it, it's not worth it,'" Steingrebe said. She said it's typical for landlords to deduct for carpet cleaning at the end of the lease. Renters can hire their own company to do it and leave the receipt, but if the job is sub-par, they could end up paying twice. Renters do have the right to use their property and not be charged for normal wear and tear. For instance, it's totally fine to nail a picture to the wall. Doing something bigger, however, such as a mounting a large TV to a wall, could lead to extra withdrawals from your security deposit. 2837

SAN DIEGO (KGTV) — San Diego is in bloom, making it the perfect time to get out and take in the area's natural beauty.The annual Cherry Blossom Festival returns to the Japanese Friendship Garden, bringing beautiful cherry blossoms to town with a multi-day festival. Julian will celebrate another flower as well, during their annual Daffodil Show.Head out to Santee Lakes and enjoy a night of games and entertainment, highlighted by a lake covered in lanterns during 1000 Lights Water Lantern Festival. And the beauty of voice hits Balboa Park, and a day full of choirs perform at the Spreckels Organ Pavilion during the San Diego Sings! Festival.RELATED: Things to do for free in San Diego CountyIt's a bit of a reverse for some, but beauty is in the eye of the beholder. Del Mar Fairgrounds will host an annual Ugly Dog contest, where you guessed it, we find the area's ugliest dog. The event will also hold contests for cutest dog and other categories as well.Here's a look at this weekend's happenings:THURSDAYDry Bar ComedyWhere: American Comedy Company; Cost: Bringing "comedy for everyone" to San Diego, Dry Bar Comedy heads to American Comedy Co. for a night of laughs free from vulgarities. The tour's online presence has generated more than 1 billion views and comics have been featured on late night stages including The Tonight Show, Jimmy Kimmel, Comedy Central, and more.26th annual San Diego Latino Film Festival Where: AMC Fashion Valley; Cost: - 0(Thursday - Sunday) The 26th annual San Diego Film Festival celebrates Latino culture, history, and arts over 11 days featuring more than 160 films from the U.S., Latin America, and Spain. The festival will host Q&A sessions with filmmakers and actors, a food,beer, and wine festival, and more experiences centered around Latino cinema.FRIDAY14th annual Cherry Blossom FestivalWhere: Japanese Friendship Garden of San Diego; Cost: (Runs Friday - Sunday) You don't have to head far from the county to enjoy springtime flowers. The Japanese Friendship Garden's Cherry Blossom Festival returns, opening up to the public for a festival featuring crafts, performances, a beer & sake garden, street food and blossoming cherry trees!7th annual Bankers Hill Arts & Crafts Beer FestivalWhere: The Abbey; Cost: - Enjoy tastes of delicious craft beer, bites from local eateries, and live music while artists showcase works covering paintings and fine art to photography and collaging to more, benefiting the Bankers Hill Business Group.SATURDAYWanderlust 108Where: Embarcadero Marina; Cost: - 0Celebrate an active lifestyle with a day filled with outdoor yoga, meditation, and lawn activities at Wanderlust 108. Lace up your shoes for a 5K run or walk and enjoy guided yoga from trainers at the Embarcadero!1000 Lights Water Lantern FestivalWhere: Santee Lakes; Cost: - Santee Lakes will be be covered in light as guests set decorated lanterns across the water during 1000 Lights Water Lantern Festival. Enjoy the sunset with games and entertainment, and food before the festival lights up the night.San Diego Sings! FestivalWhere: Balboa Park, Spreckels Organ Pavilion; Cost: FreeEnjoy a day filled with music from by a variety of choirs in Balboa Park. More than two dozen performances by choirs and organists will filled the day at Spreckels Organ Pavilion with music in this day-long free concert.Open House San Diego - San Diego's most iconic buildingsWhere: Various locations around the city of San Diego; Cost: FreeOn Saturday and Sunday, learn more about some of the more iconic buildings in areas such as downtown San Diego, Barrio Logan, Balboa Park and La Jolla. Join the tour to find out the history of these structures and other hidden gems. Tourgoers can also take part in a photo contest for prizes.SUNDAYAnnual Butterfly JungleWhere: San Diego Zoo Safari Park; Cost: - (Runs Saturday - Sunday) Walk through a greenhouse of butterflies of all colors and sizes at the San Diego Zoo Safari Park. Guests can feed butterflies and be guided through an array of the zoo's Butterfly Jungle inhabitants.15th annual Julian Daffodil ShowWhere: Julian Town Hall; Cost: Free(Runs Saturday - Sunday) Get ready for even more flowers this spring. Julian celebrates the spring season amid blooming excitement for local flowers with their Daffodil Show. Head up to the scenic mountain town for some seasonal beauty and stop in to smell the flowers at the show! 24th Annual Ugly Dog contestWhere: Del Mar Fairgrounds; Cost: - 0It's really a contest for a good cause. Del Mar's Ugly Dog contest will raise money for the Helen Woodward Animal Center's Animeals program for seniors. But the contest isn't just for the "ugliest" dog! Contests for cutest puppy, best trick, best costume, "looks most like its owner," and more will be held. 4846

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