濮阳东方妇科价格不贵(濮阳东方医院几点上班) (今日更新中)

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched."  6969

LEXINGTON, Ky. — A year of unexpected stress has caused at least one dietitian to see more patients with significant weight gain and heart disease, which she warns could become worse over the holidays.University of Kentucky Gill Heart and Vascular Institute Cardiopulmonary Rehab Dietitian Shorus Minella said the pandemic has caused weight gain to become an issue with more and more people to remain indoors and be more inactive than usual.Minella said an easy tip to staying healthy is to keep healthy foods on hand for snacking.She also shared her trick for practicing moderation "When you do feel like you want to snack and you're feeling stress to help pull back how much you're actually eating," Minella said. "I love potato chips so I make sure I put them in a little small bowl. Take the bowl away from the kitchen and away from the bag and once I'm done eating them out of that container that bowl, I'm done with my chips."With the season for special holiday treats in full swing, Minella explained how everyone can keep within their diets."You don't want to deprive yourself of the things that you possibly wouldn't get day-to-day all year round," she said. "So I like to say, save the calories for the little special things that you usually don't have. So if you don't usually have those Christmas gingerbread cookies, make room for them have room for them, maybe cut out some soda or sweet tea that you usually would have, and save your calories on the special things that you wouldn't get all year round."She encouraged those preparing food to trade out healthier options like low-fat milk for whole milk on a recipe.With heart disease ranking as the leading cause of death in the U.S. in 2019 and with obesity numbers on the rise throughout the country since 1999, Minella said small changes like making a bit of time for exercise can go a long way."If you can't go outside because of the weather, making sure to do chair exercises, or I like to remind people just marching in place, counts as well," she said. "So just something to get moving a little bit more. And then when you do feel like eating, think about if you're bored or not, or if you're hungry and think about those hunger cues as well."Minella encouraged everyone to try a heart-healthy diet that tries to reduce the amount of saturated fat by focusing on lean meats like chicken, turkey and fish."If you're paying attention to what you're eating, you're paying attention to enough to, I don't want to say feel 'bad,' but you're paying attention enough to have those feelings and that's great start," she said. "So be gentle with yourself every day is a new day and just try to practice this mindful eating."This story was originally published by Claire Kopsky on WLEX in Lexington, Kentucky. 2779

LAKE ALFRED, Fla. -- A Polk County, Florida family is outraged after they say their 7-year-old was forced to scrub school floors with a toothbrush as punishment.The elementary student reportedly misbehaved last week at Lake Alfred Elementary, when her teacher sent the student next door for "corrective action."According to the family, the 7-year-old was told to scrub the floors with a toothbrush.They also claim teachers told her to clean the entire floor, and when she was done she was told to then clean the counters.Family members say she was forced to do this throughout the day and was not able to participate in regular classroom activities. The family says they were not made aware of the misbehavior or the punishment their daughter received. The parents only found out after their 7-year-old was complaining of back pain after school and they asked why she was in so much pain.This is an excerpt from a letter written to Scripps station WFTS in Tampa from the student’s Aunt, Kiara Francisco: 1026

LAKE HUGHES, Calif. (CNS) - A fire burning near the Lake Hughes area is 12% contained Friday morning after scorching 11,000 acres and destroying three structures, authorities said.Firefighters, meanwhile, braced for dangerously hot weather caused by a heat wave this weekend."Near critical fire weather conditions could develop Friday afternoon and evening as gusty onshore winds could combine with warm and dry conditions in place," the Los Angeles County Fire Department reported Thursday.Crews were able to take advantage of improved fire weather conditions Thursday with slightly lower temperatures and moisture from the former hurricane Elida moving across the area, the department said."Current objectives include keeping the fire north of Castaic Lake, south of Highway 138, east of Red Rock Mountain and west of Tule Ridge," the department said.The fire was reported at about 3:30 p.m. Wednesday near North Lake Hughes Road and Pine Canyon Road in the Angeles National Forest and was 12% contained as of 7 a.m. Friday, according to the u. S. Forest Service, which was battling the blaze with Los Angeles County Fire Department crews and assistance from the Los Angeles, Culver City, Beverly Hills, Monterey Park, Long Beach and Santa Monica fire departments.The fire's size was listed as 11,000 acres Thursday night, with three structures destroyed and 5,420 threatened, according to the Los Angeles County Fire Department. No injuries have been reported."There have been areas of this fire that have not burned in decades, (and) it's in inaccessible terrain, which has added to the complexity of the fire," said Los Angeles County Fire Department Chief Daryl Osby.Although some structures were lost, a number of structures were saved by firefighters, he said."It's going to be a hot, dry summer -- and it's going to be a very, very hot, dry weekend," Osby said.On Wednesday, the fire west of Palmdale had a "rapid rate of spread," amid temperatures in the mid-90s, low humidity and gusty winds, according to the U.S. Forest Service. The forest service and county fire departments quickly called in second-alarm responses.The fire was entirely on federal land, according to the Los Angeles County Fire Department.Mandatory evacuations were ordered for the area east of Ridge Route Road, west of Lake Hughes Road, north of Pine Canyon Road and Lake Hughes Road, and south of state Route 138, said Los Angeles County sheriff's Capt. Ron Shaffer of the Palmdale Station.More than 100 structures were affected in the evacuation area, including primary residences and outbuildings, in the communities of Lake Hughes and Pine Canyon, officials said.Evacuation centers were set up for displaced residents at Highland High School in Palmdale and the Castaic Sports Complex."In this evacuation, unfortunately because of COVID protocols, a shelter is not actually established, people will have to stay in their cars," Shaffer said earlier. People staying in their cars at a center are allowed to have small animals with them.Animal boarding was made available at Castaic Animal Care Center, Lancaster Animal Care Center, Palmdale Animal Care Center and the Antelope Valley Fairgrounds, according to the American Red Cross Los Angeles.San Francisquito Canyon Road was closed from Stater Lane to Spunky Canyon Thursday evening, as well as Three Points Road from State Route 138 to Pine Canyon.More than 1,500 firefighters, along with three helicopters, five water tenders, and 173 engines, were assigned to the firefighting effort.The cause of the fire was under investigation. 3581

Lina Crisostomo's SATs are coming up next week, but college test prep has taken a backseat to funerals, vigils and walkouts.It's been like that since a gunman stormed Marjory Stoneman Douglas High School, killing 17 people and sending Lina running from campus."Homework doesn't really seem that important now," she said Friday, the day before her 17th birthday. "My attention has changed to fighting for these 17 lives."  434

来源：资阳报