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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Talk about being blindsided by an ex.The skilled Elisabeth Moss steps out of her "The Handmaid's Tale" bonnet to play Cecilia, the spunky heroine 158

Sen. Kirsten Gillibrand dropped out of the race for the 2020 Democratic presidential nomination Wednesday afternoon, ending a campaign that failed to catch on despite the New York Democrat's substantial campaign war chest and high profile position."Today, I am ending my campaign for president," Gillibrand said on Twitter. "I am so proud of this team and all we've accomplished. But I think it's important to know how you can best serve. To our supporters: Thank you, from the bottom of my heart. Now, let's go beat Donald Trump and win back the Senate."Gillibrand's decision to drop out comes as she was on the cusp of failing to qualify for the third Democratic primary debate as she was unable to meet the donor and polling thresholds outlined by the Democratic National Committee.Gillibrand, in a sign that the campaign viewed qualifying for the third debate as critical, had spent millions on TV and digital ads aimed at boosting her support. But those efforts failed to break Gillibrand out of the pack of candidates polling under 1% nationally.Gillibrand centered her campaign on fighting for equality, especially for women, something that she has also made central to her time in the Senate. 1212

TAMPA, Fla. — The convenience of smart speakers – like Amazon’s Echo, Google’s Home and Apple’s HomePod – could come at a price to your privacy and these popular tech tools may be recording you even when you’re not using them, the I-Team uncovered.Justin McDonald told I-Team Investigator Adam Walser that he loves his Amazon Echo. With simple commands, McDonald controls his ceiling fan, thermostat and smart tv without getting off his couch.“I think I have between 10 and 12 internet connected devices,” said McDonald, who regularly asks Amazon’s virtual assistant “Alexa” about the news, weather and stock reports. “It’s worked its way into our morning routines.”He even has an additional Echo in his infant son’s room.When asked what Alexa knows about him, Manatee County resident McDonald replied, “More than I’d like to know probably.”The I-Team asked Justin McDonald to listen to his own Amazon audio data, which can be accessed through Amazon’s privacy dashboard. 983

Scientists working for a NASA-funded project at the University of Arizona said that a possible "mini moon" is currently orbiting the Earth. Kacper Wierzchos of the Catalina Sky Survey tweeted this week that an object, 2020 CD3, has been captured by Earth's gravitational pull, and is temporarily in orbit around the Earth. The object is not very large, only 6 to 11 feet, Wierzchos said, but he added it is still an extraordinary discovery. "it's a big deal as out of ~ 1 million known asteroids, this is just the second asteroid known to orbit Earth (after 2006 RH120, which was also discovered by the Catalina Sky Survey)," he tweeted. 2020 CD3 began orbiting the Earth three years ago. Elon Musk, the head of Tesla, jokingly tweeted, "It’s not mine." Tesla sent a Roadster into space in 2018. BIG NEWS (thread 1/3). Earth has a new temporarily captured object/Possible mini-moon called 2020 CD3. On the night of Feb. 15, my Catalina Sky Survey teammate Teddy Pruyne and I found a 20th magnitude object. Here are the discovery images. 1049