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WASHINGTON, March 4 (Xinhua) -- New data suggest that the epilepsy drug Topamax (topiramate) and its generic versions increase the risk for the birth defects cleft lip and cleft palate in babies born to women who use the medication during pregnancy, the U.S. Food and Drug Administration (FDA) said Friday in a statement.Before prescribing topiramate, approved to treat certain types of seizures in people who have epilepsy, health care professionals should warn patients of childbearing age about the potential hazard to the fetus if a woman becomes pregnant while using the drug, the FDA said.Topiramate also is approved to prevent migraine headaches, but not to relieve the pain of migraines."Health care professionals should carefully consider the benefits and risks of topiramate when prescribing it to women of childbearing age," said Russell Katz, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Alternative medications that have a lower risk of birth defects should be considered."Cleft lip and cleft palate, collectively called oral clefts, are birth defects that occur when parts of the lip or palate do not completely fuse together early in the first trimester of pregnancy, a time when many women do not know they are pregnant.The defects range from a small notch in the lip to a groove that runs into the roof of the mouth and nose, possibly leading to problems with eating, talking, and to ear infections. Surgery often is performed to close the lip and palate and most children do well after treatment.Data from the North American Antiepileptic Drug (AED) Pregnancy Registry indicate an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy. Infants exposed to topiramate as a single therapy experienced a 1.4 percent prevalence of oral clefts, compared with a prevalence of 0.38 percent - 0.55 percent in infants exposed to other antiepileptic drugs.Infants of mothers who did not have epilepsy and were not being treated with other antiepileptic drugs had a prevalence of 0.07 percent. Similar data from the United Kingdom Epilepsy and Pregnancy Register supported the North American AED Pregnancy Registry data.According to the FDA, before starting topiramate, pregnant women and women of childbearing potential should discuss other treatment options with their health care professional.

WELLINGTON, May 22 (Xinhua) -- One in every eight women giving birth in a New Zealand hospital last year was Asian, local media reported Sunday.In the country's most populous city, Auckland, 5,149 Asian women gave birth, more than double the number of 15 years ago, the New Zealand Herald reported.Last year was the first year in the city when more Asian women gave birth than indigenous Maori women, who registered 5,015 births.Citing figures from the government statistics agency, Statistics New Zealand, the report said the majority of women nationwide who gave birth last year were still of European descent, accounting for 43,965 of last year's 63,897 births.But more women of other ethnic backgrounds were also becoming mothers, including those from the Middle East, Latin America and Africa.Auckland University head of obstetrics and gynaecology, Professor Lesley McCowan, said the increase reflected New Zealand is an increasingly multicultural society.

CHICAGO, Jan. 21 (Xinhua) -- Chinese President Hu Jintao left Chicago for China on Friday after concluding a state visit to the United States, during which he and his U.S. counterpart Barack Obama agreed to build a China-U.S. cooperative partnership based on mutual respect and mutual benefit.Hu, who began his four-day visit Tuesday, had extensive and in-depth discussions with Obama at the White House on Wednesday on major bilateral, regional and world issues.Chinese President Hu Jintao shakes hands with U.S. President Barack Obama during a bilateral meeting at the White House in Washington, the United States, Jan. 19, 2011.The two sides reached "important agreement on China-U.S. relations and major international and regional issues of shared interests," the Chinese president said when he and Obama met the press following their discussions."We both agree to further push forward the positive, cooperative and comprehensive China-U.S. relationship," Hu said, adding that both sides also pledged to forge "a China-U.S. cooperative partnership based on mutual respect and mutual benefit" for the benefit of the two countries and beyond.

WASHINGTON, March 30 (Xinhua) -- A trace amount of radioactive iodine has been found in a sample of milk from the west state of Washington, the U.S. Environmental Protection Agency and the Food and Drug Administration (FDA) said Wednesday.According to a joint statement from the two agencies, results from a screening sample taken March 25 from Washington detected 0.8 pCi/L of iodine-131, which is more than 5,000 times lower than the Derived Intervention Level set by the FDA.These types of findings are to be expected in the coming days and are far below levels of public health concern, including for infants and children, the statement said.Iodine-131 has a very short half-life of approximately eight days, and the level detected in milk and milk products is therefore expected to drop relatively quickly."Radiation is all around us in our daily lives, and these findings are a minuscule amount compared to what people experience every day. For example, a person would be exposed to low levels of radiation on a round trip cross country flight, watching television, and even from construction materials," said Patricia Hansen, an FDA senior scientist.