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SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906

SAN DIEGO (KGTV) — While Willy Wonka isn't expected to show up to San Diego Comic-Con, his famous promotion will appear before hungry fans.For the fourth year, the San Diego Convention Center has created its own chocolate bars that will be sold inside the center during Comic-Con, the center announced this week. A total of 3,800 chocolate bars will be made and sold near Ballroom 20 for each.But the real surprise comes underneath the wrapper for four lucky fans. 10NEWS' COMIC-CON CENTRALThe convention center has hidden four "golden tickets" inside the bars, according to the center. Those who find a golden ticket will be award a 0 Starbucks gift card — the perfect treat for an SDCC attendee.This year's four themed flavors include "Stranger Smores" (milk chocolate, crispy waffles, and maple syrup marshmallows), "Battle Bar" (dark chocolate and raspberry crisps), "Dragon Smoke" (smoked dark chocolate and chipotle dust), and "50/30" (sprinkles, birthday cake, and white chocolate).The last bar was named in commemoration of the 50th SDCC and convention center's 30th anniversary. The chocolate bars will be made in-house by the convention center's food and beverage partner, Centerplate, in collaboration with Executive Chef Daryl O'Donnell and Pastry Chef Mathew Haven.Comic-Con begins on July 17, running through July 21. 1345

SAN DIEGO (KGTV) - Two rallies were held at Chicano Park Monday one day before President Trump visits the area to reportedly tour the U.S.-Mexico border. 161

SAN DIEGO (KGTV) - Two thieves prowled an entire neighborhood in Oak Park looking for something very specific on the vehicles.Along Blackton Drive, the sense of safety is shattered for David Cabrera.  Late Wednesday morning, Cabrera and his wife returned home to a neighbor telling them to check their license plate.  He discovered the registration sticker on his truck stolen. He had sliced his sticker into eight different sections as a precaution but it didn't help.Cabrera's surveillance cameras revealed the thieves:  a man and a woman walking together. A tree obscures the camera's view, but a woman can be seen behind Cabrera's truck, while the man stands and looks around.  The woman gets up and the two walk off.Seconds later, a neighbor saw the same woman peeling off a sticker from another car and the neighbor ran out of her kitchen to confront her.  That neighbor told the woman to put it back.  The woman got verbally aggressive but did put the sticker back.Neighbors called 911 but the thieves took off.  After Cabrera posted details on the Nextdoor app, five other neighbors reported also getting hit that morning."It's a feeling of violation. You want to feel safe in your own neighborhood," said Cabrera. 1275

SAN DIEGO (KGTV) --  Authorities have identified the man who died after he and another man played a consensual "punching game" in a Gaslamp Quarter sports bar early Saturday morning.Corey Poole, 27, had apparently gone out drinking at the downtown sports bar with a group of friends. The group arrived at the Jolt’n Joe’s at 379 Fourth Avenue just before 1 a.m. Police say both men were drinking when they decided to have a punching contest.Police say that Poole and a friend began "consensually sparring" and punching each other in the chest.  During the game, Poole fell to the ground and became unresponsive, the San Diego County Medical Examiner's Office said.Staff at the bar performed CPR on the 27-year-old who was taken to Scripps Mercy Hospital where he died about an hour later."The decedent and a friend began consensual sparring, consisting of concurrently punching each other with closed fists on the chest," the Medical Examiner's Office said, describing what police had previously called "playing a punching game.""After receiving several punches to the chest, the decedent was struck and immediately collapsed and became unresponsive," the Medical Examiner's Office said.Officials are still working to determine whether Poole's death was an accident, a homicide or something else.Poole's friend, who remained at the location and was hospitalized for chest pain, was not arrested and it's unclear if charges against him will be filed. 1502