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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene. In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma. More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.
JIANGYIN, Jiangsu, July 1 (Xinhua) -- China's manned deep-diving submersible, the Jiaolong, embarked on a journey on Friday during which it will make a 5,000-meter dive in the Pacific Ocean.During the dive, the submersible will undergo several operational tests in which it will take photos, shoot video, survey seabeds and take samples from the ocean floor, according to Jin Jiancai, deputy director of the submersible's diving test program team.The tests will be conducted in the Pacific Ocean in accordance with a contract signed between the China Ocean Mineral Resources Research & Development Association and the International Seabed Authority (ISA).The submersible is scheduled to spend 47 days at sea, according to a statement from the Ministry of Science and Technology.A submersible differs from a submarine, as it typically depends on another vessel or facility for support.The Jiaolong, designed to reach a depth of 7,000 meters, completed 17 dives in the South China Sea between May 31 and July 18 last year, reaching 3,759 meters during its deepest dive.In the year since the submersible's last dive, program team members have made several technical improvements to the submersible and its support vessel, Jin said.Jin said the program team members are "very confident" about the test.He also stressed that the test will be carried out in accordance with the provisions of the United Nations Convention on the Law of the Sea as well as the ISA's rules and regulations.The Jiaolong is the world's first manned submersible designed to reach depths of 7,000 meters below sea level, according to Xu Qinan, the submersible's chief designer.
BONN, Germany, June 17 (Xinhua) -- The latest United Nations (UN) climate talks ended here on Friday with no surprise -- some " technical issues" saw some progress, as delegates usually said, while major disagreements remained.The two-week UN climate negotiations have made "clear advances" on such issues as extending carbon trading mechanisms, climate fund management and slowing deforestation, Christiana Figueres, UN Framework Convention on Climate Change (UNFCCC) executive secretary, said at a closing press conference.Figueres said delegates from 183 countries stepped forward with a technology mechanism to boost global green technology sharing. The mechanism will include a Climate Technology Center and Network to establish a worldwide clean technology stakeholder community.As for the implementation of a comprehensive package of the Cancun summit last year, this Bonn session has "paved the way" for progress at the next UN ministerial-level climate conference, which is to be held in Durban, South Africa from Nov. 28 to Dec. 9, Figueres said."Strong convergence has emerged on how the Adaptation Committee will be governed, what its composition will be and what its specific role will be," she said. "This progress means that the Committee could be fully operationalized at Durban."The UN climate chief stressed that governments, business circles and civil society cannot solve issues related to climate change "in one meeting," and climate talks are "the most important " negotiations the world has ever seen."The Bonn meeting is practical, focusing on concrete issues. In general, the negotiating process is moving forward step by step and on the right track," Su Wei, China's chief negotiator, told Xinhua on Friday."Despite setbacks and reversals, parties are taking climate change seriously and are willing to promote the negotiations under the Bali Roadmap," he said. "In the past two weeks, contact groups are busy making informal consultations on various topics.""Admittedly, in some key areas, there is a gap among parties," Su said.During the meeting, many delegates and observers have complained that the pace of negotiation was unbearably slow, especially against the backdrop of a new warning from the International Energy Agency, which said the global energy-related carbon emissions rose to a record high in 2010 despite decade-long efforts on curbs.Experts said one of the main hurdles in current talks was still the old topic -- the fate of the Kyoto Protocol, the sole legally- binding pact on industrial countries' emission cuts set to expire at the end of 2012.The protocol, which binds 37 rich countries, has been crippled since Cancun, as Japan, Canada and Russia have clearly stated they would not extend the pact's second commitment period after 2012.The United States, which never ratified the treaty, said it would not accept any legal deal unless other major economies have similar emission constraints.The European Union (EU), the last major bloc that is open to the renewing of the Kyoto Protocol, said its supportive attitude should not be taken for granted. The EU said it would not unilaterally step up efforts on combating climate change if other nations are not willing to do the same.Meanwhile, developing countries insisted that the updating of the Kyoto Protocol remains "the very core issue" of current talks, asking rich nations to shoulder their historical responsibilities and preserve the pact as a major legally-binding instrument to tackle climate change.The Group of 77 and China, representing over 130 developing nations, have said that the renewal of the Protocol should be the priority for Durban.On Friday, Figueres said that "resolving the future of the Kyoto Protocol is an essential task this year and will require high-level political guidance.""By Durban, governments need to come forward with options that will be acceptable to all parties," she said, adding that high- level contacts are necessary to break the ice.She told reporters that environment ministers are due to meet in Berlin from July 3 to 4, known as a continuation of last year's ministerial-level informal talks held in the town of Petersburg near Bonn. Moreover, world leaders are due to discuss climate change on the sidelines of the UN General Assembly in September.Before the Durban summit, delegates have agreed to hold an additional round of climate talks in late September or early October, Figueres revealed.
OTTAWA, Sept. 29 (Xinhua) -- Climate change could cost Canada billions of dollars a year by the end of this decade, a government funded study group announced Thursday.The National Round Table on the Environment and the Economy said the cost of climate change for Canada could start at roughly 5 billion Canadian dollars per year in 2020 and increase to between 21 billion and 43 billion per year by 2050. Those costs would come from shoreline damage, public health problems, and disruptions to the economy.It also predicted a slight increase in deaths in major cities from heat and air pollution.The round table researchers estimated the cost of climate change is expected to be roughly 0.8 percent to 1.0 percent of GDP -- or 43 billion Canadian dollars a year -- by 2050, if the problem is allowed to worsen.But the report did not address possible benefits, such as reduced demand for hea
WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.