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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
Public speaking is one of the biggest fears. About 7 percent people in the U.S. have the fear, that's about 27 million Americans. But there are some steps you can take in your everyday life to beat the fear for good.This is the moment Anyeik Artis and all her classmates will see if she's overcome her fear of public speaking."My name is Anyeik and my speech is about what we think we are," Artis says. "It's all about the mindset you choose to be in that will determine your outcomes in life."She stuck to her notes and gave personal examples."My goal in life was to go to college when I was in high school," Artis explains.Eventually the notes were gone and the speech ended much differently than it began."Not everybody is going to be the same because our thoughts are so different," Artis says in closing. "So thank you."She made it back to her seat relieved."I kept shaking but I got through it.," Artis says.Then, she waited for feedback."There was way less fidgeting," said Oldile Fazioni, Artis' teacher at Community College of Denver. "You were more present, you were really looking at us strong with the strong eye contact."Fazioni helps her students overcome their fears. The first step is a starting exercise, where students make eye contact with their audience one person at a time."Try to change the speech from a speech to the audience to a conversation with that person," Fazioni says.Next, she teaches students to be in touch with their bodies. It works by consciously feeling your hands and feet to take attention away from the fears in your mind and become more present. But the biggest key she says is concentrating on content."The moment that the student is able to move away from the mind and into the verbal message and making sure that it is clear I see a huge shift in the confidence of the students," Fazoni says.And lastly, celebrate! Recognize how far you've come, even if you're not perfect."Let's value the mistakes just as much as we value the success because through the mistake or through their fault we really learned to become better speakers," Fazioni says.Fazioni says you don't have to be in a class to try these things out. You can practice in small group conversations. So when that big speech does come, you'll be ready. 2309

RAMONA, Calif. (KGTV) - The owners of a Ramona camel farm are concerned about a new California senate bill which could ban the animals from taking part in parades and shows. Known as the “circus cruelty” bill, it would stop Gil and Nancy Riegler from the Oasis Camel Dairy from transporting camels to events like parades, fairs, or Christmas nativity shows. Supporters of the bill say it will prevent animal abuse. 422
President Donald Trump travels to Pittsburgh on Tuesday after the worst anti-Semitic crime in American history, bringing with him a pulsing anger that his rhetoric is being blamed for the attack and intent on proving to his critics he can behave like a president.For Trump, the role of consoler has sometimes come uneasily and, in his view, without tangible benefit. Trump has complained in the past that so-called "presidential" moments have gone unnoticed by his critics and unheralded in the media, leading him to wonder what the point of it all was.This weekend, after Trump forcefully decried anti-Semitism during campaign appearances, he again protested to confidantes that the message wasn't received with praise, according to people familiar with the conversations. Along with many of his aides, he viewed the continued questions about his divisive rhetoric as petty partisan attacks launched by his political opponents.Still, after discussions with advisers that included daughter Ivanka Trump and son-in-law Jared Kushner, who are Jewish, Trump declared his intent to visit Pittsburgh. The trip comes amid a last-minute midterm campaign push and has forestalled, for now, a planned address on immigration.Trump has expressed concern his midterm messaging could be knocked off-kilter by the attack. Pittsburgh's mayor called on Monday for Trump to wait to visit until after burials are complete, but with an 11-rally itinerary set for the end of the week, there was little flexibility in the President's schedule.His daughter and Kushner, will join Trump in Pittsburgh, along with first lady Melania Trump, who has sometimes worked with mixed results to soften her husband's public image. He is expected to meet with some members of the Tree of Life congregation, who lost 11 members when a gunman opened fire inside the synagogue on Saturday morning. 1883
President-elect Joe Biden still has two more months before he is sworn in, and while many Republicans are finding it difficult to accept his win, Biden is meeting with key Democrats in hopes of having a deal in place for an economic stimulus plan. Biden has spoken with the top two Democrats in Congress — but not their Republican counterparts yet.Biden’s transition team announced Thursday that he spoke by phone with House Speaker Nancy Pelosi and Senate Democratic leader Chuck Schumer, thanking them for their congratulations and expressing “his commitment to uniting the country after a hard-fought campaign.”The three spoke about “intensifying” the country’s coronavirus response and coping with the economic fallout the pandemic has inflected. They also discussed the “urgent need” to use the lame duck congressional session to approve bills on slowing the spread of COVID-19, as well as economic relief for “working families and small businesses, support for state and local governments trying to keep front-line workers on the payroll,” expanded unemployment insurance and expanded access to affordable health care.Biden said Tuesday that he had not spoken to Senate Majority Leader Mitch McConnell, though the two have been friends for years.But there is still optimism this week among some on Capitol Hill a deal on economic stimulus can be approved during the lame duck session. "The need is too urgent. We need to do it now. Not wait. Families are going to be coming together, even though in smaller groups for Thanksgiving. They should have the assurance of another stimulus payment by Thanksgiving. It's doable," said Sen. Richard Blumenthal, D-Connecticut. 1680
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