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发布时间: 2025-05-24 13:09:38北京青年报社官方账号
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LOS ANGELES, Oct. 3 (Xinhua) -- An organizer of the World Stem Cell Summit says one of the key problems medical researchers face these days is how to apply their findings in the real world."How do you take the phenomenal scientific research going on in labs and translate it into medical treatments,?" said Bernie Siegel, the founder and co-chair of the summit and executive director of the Genetic Policy Institute, which organized the event."It's a big job to do this, and more than just the science," Siegel said, noting that in a growing field now moving beyond basic lab research, the aim is to connect the people who do the work with those who finance it.The three-day summit, which opened Monday in Pasadena, features more than 150 top international speakers and 50 hours of programming with leaders from science, pharmaceutics, business, policy, ethics, law and other fields.The cell therapy industry, a "nascent" field, has emerged to be a potentially multi-billion business with unlimited potential, Siegel said.Stephen Dalton, a University of Georgia professor, reported that one of the biggest developments in stem cell research in the past year was the realization that cells can be transdifferentiated from one state to another without returning to a pluripotent state.Dalton said the principle was previously supported by a few isolated examples but it was not until 2010 that the idea was widely accepted.Mark Sussman, a professor from San Diego State University, called the identification of lung stem cells from human tissue samples capable of regenerating the highly complex and specialized structures of mature lungs a breakthrough in lung biology and regenerative medicine.He said results presented by the Anversa group in the New England Journal of Medicine demonstrate that human lung stem cells can be expanded in vitro and also retain the capacity to integrate into adult tissue upon introduction into mice.The study, Sussman said, has opened up an entirely new field of possibilities for lung regeneration and potential therapeutic applications for many conditions where treatment options are either very limited or nonexistent.

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WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."

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BEIJING, Oct. 21 (Xinhua) -- China's State Councilon Thursday called ordered improved, innovative administration in environmental protection, according to a statement.In a statement published on the central government's website, the State Council listed a series of guidelines on environment-related issues, saying that it will step efforts to address prominent environmental problems that affect people's lives and sustainable development.The statement ordered strictly implementing environmental impact assessment, vigoroulsy developing environmental protection industry, and ensuring nuclear and radioactive safety.It called for implementing economic policies beneficial to environmental protection.The statement also ordered local governments at all levels to attach more importance to environmental protection, noting ecological conditions should be considered in evaluating the performance of local leaders.

  

BEIJING, Nov. 27 (Xinhua) -- China's industrial enterprises saw their profits increase 25.3 percent year-on-year in the first ten months of 2011, slowing down from the year's previously recorded figures, official data showed Sunday.Growth in the January-October period was 1.7 percentage points lower from that of the first three quarters, the National Bureau of Statistics (NBS) said in a statement.It marked a gradual downshift from the 34.3-percent year-on-year growth seen during the January-February period and the 28.7-percent growth seen during the first half of the year.Profits realized in the first ten months amounted to 4.12 trillion yuan (650 billion U.S. dollars), the NBS said.The NBS compiled the figures using data collected from a pool of industrial businesses with at least 20 million yuan in annual sales revenues each.In October alone, industrial profits expanded 12.5 percent year-on-year to 438.3 billion yuan, the NBS said.Among 39 industries surveyed, 36 sectors reported profit growth in the first ten months. The oil refining, coking and nuclear-fuel processing sector saw profit plunge 89.8 percent year-on-year.Private businesses posted the fastest profit growth, with a year-on-year rise of 44.3 percent, followed by collectively owned enterprises of 33 percent, equity-holding companies of 30.3 percent, state-owned enterprises of 16.6 percent and overseas-funded firms of 11.6 percent.China's industrial production growth rate will moderate due to economic turmoil in Europe and the United States and weakening domestic demand brought about by a tightened monetary policy, Huang Libin, an official with the Ministry of Industry and Information Technology, said last week.China saw its economic growth slow to 9.1 percent in the third quarter of this year from 9.5 percent in the second quarter and 9.7 percent in the first quarter.

  

HELSINKI, Nov. 7 (Xinhua) -- A data leak was uncovered in Finland Saturday, in which personal details of around 16,000 people were uploaded onto a file-sharing website, according to Finnish media report on Monday.This act of sabotage is the largest ever of its kind in Finland. The data leak is being looked into by the Finnish National Bureau of Investigation.Anonymous Finland claimed on Monday responsibility for the publication of personal details of thousands of Finns. The group temporarily published a sample of information on 16,000 people as proof of the hack. The hack was motivated by an apparent desire to shame the Finnish government into improving data security.Finnish National Bureau of Investigation has not confirmed the claims that a loose group of hackers known as Anonymous was behind the data leak.The list that was put on the Internet contains the names, full social security numbers, addresses, telephone numbers, street addresses, and email addresses of the victims. Several upper secondary vocational education institutions are on the list, and some civil servants and students of the Police College of Finland are mentioned by name.Finnish police have confirmed that the names of some Finnish Defense Forces staff are on the list. Finnish Defense Forces found out that fewer than 10 of its employees are included, and has informed these people. The military said the leak did not pose a security threat.

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