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T-Mobile and Sprint finally agreed to a massive telecom merger after years of negotiations punctuated by two breakups.The  billion merger, announced Sunday, values Sprint near its current share price of .50.The tie-up would position the telecom companies as fiercer competitors to Verizon and AT&T, which have long dominated the US market."I'm excited to announce that @TMobile & @Sprint have reached an agreement to come together to form a new company -- a larger, stronger competitor that will be a force for positive change for all US consumers and businesses! Watch this & click through for details." said T-Mobile CEO John Legere, in a tweet Sunday.A report that the deal was getting close drove up Sprint's stock price by 8% on Friday and T-Mobile's price edged up as well. The stock price for SoftBank, a Japanese conglomerate with a majority stake in Sprint, rose by 3%.Sprint and T-Mobile first discussed a merger in 2014 but scrapped it because of concerns about regulatory challenges from the Obama administration.The companies expected to have a better shot at the merger under the Trump administration.Sprint stock tanks as T-Mobile merger said to collapseSoftBank CEO Masayoshi Son met with Trump the month before he took office to talk up an investment in US businesses.A few weeks later, T-Mobile's Legere said he was open to "various forms of consolidation" when asked about a potential merger with Sprint and SoftBank under the Trump administration.But last November, after much speculation, the two companies issued a statement saying they "have ceased talks.""While we couldn't reach an agreement to combine our companies, we certainly recognize the benefits of scale through a potential combination. However, we have agreed that it is best to move forward on our own," Marcelo Claure, the Sprint CEO, said at the time.Sprint and T-Mobile's announcement is just the latest step in an ongoing movement towards telecom consolidation. AT&T is in talks to acquire Time Warner, which owns CNN and CNNMoney. The outcome of that billion merger-in-the-making depends on a case in federal court, which is pending the decision of the judge. 2203

There will inevitably be people who want to vote in person who may now be positive for the coronavirus, showing symptoms of COVID-19 or who are quarantining.The Centers for Disease Control and Prevention (CDC) has reinforced the fact that Americans have the right to vote, regardless of whether they're sick or in quarantine. The agency offered this advice: 365

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

There are still roughly 700 children who were separated from their parents at the border and have not been reunified with those parents by the Trump administration, as new court filings reveal the slow pace of reuniting the trickiest family separation cases.That figure includes more than 40 children who are 4 years old and younger.While the administration maintains there is a suitable explanation for each of those cases, the filing makes clear that a large share of those children remain separated because their parents were deported without them.To date, 1,923 out of 2,654 children identified as separated from their parents have been reunified, the administration says.The number was revealed in a weekly status report on Thursday that the government is required to file as part of an ongoing lawsuit over the administration's separation of immigrant families at the border. A federal judge has ordered the administration to reunite all the families, as long as they are not ineligible due to safety concerns or other excluding factors.In a Friday court hearing, San Diego-based District Judge Dana Sabraw said the filing was nonetheless "very encouraging.""There's real progress being made and real effort being made in some of these home countries, Guatemala and Honduras," Sabraw said. "(It) looks or is very encouraging, at least, that everything is being done to locate as many of these parents as can be. So the report would indicate to the court that the efforts on the ground are productive and certainly heading in the right direction."There are 528 children in government custody who have not been reunited with a parent, including 23 who are under the age of 5, the filing said. For the first time, the administration also made clear how many children were not reunited with their parent but were otherwise released from detention: an additional 203, including 19 under the age of 5.Those children may have been released to a relative or family friend or may have turned 18 while in custody. It is possible some have since reunited with a parent outside of government custody, but it's not known how many have been able to do so.In the joint court filing with the American Civil Liberties Union, which filed the original lawsuit on behalf of separated parents, it is apparent that the two sides still disagree over how the efforts to reunify are going. While the numbers have improved slightly since last week's update, the going remains slow.Still, ACLU attorney Lee Gelernt said in court Friday that he expects the pace to "accelerate" soon.The filing also makes clear that the administration's accounting methods are painting a rosier picture of the pace of reunification than the ACLU's.According to the list given to the ACLU by the government, 412 parents were deported without their children -- a group that has remained the most difficult problem in the reunification process. That tabulation makes the number seem smaller by only counting the children still in custody with deported parents, rather than the total number of parents who were deported.There is also a dispute about how many parents have been actually found.The administration said only four of its total have not been "contacted" -- but the ACLU says only 231 parents were "reached," either by phone or in person. Of those, 183 have indicated what they want to do going forward, either reuniting with their child or allowing them to continue to seek the ability to stay in the US, and 10 have been reunited with their parents in their home country.In court, Justice Department attorneys attributed the discrepancies to out-of-date information or children being released from government custody. Administration attorney Scott Stewart said roughly two dozen children had been sent back to their home countries to be with their parents.The process is complicated on a number of levels. The information for tracking down parents and children is still raw and not always reliable, the ACLU says. Also because of two separate lawsuits, the attorneys must make sure the parents' wishes and the children's wishes about their future are aligned. Of the handful that have been resolved so far, the majority have opted to be reunited in their home countries, with a much smaller group electing to remain separated. 4318

TIJUANA, Mexico (KGTV) - Two people in a Utah-registered truck crashed into vendors and other vehicles on the Tijuana side of the U.S.-Mexico border at the San Ysidro Port of Entry Monday, Televisa reported. Two people in a black Chevy truck with Utah license plates started a fight with a pedestrian about 3 p.m. at Boulevard Gral Manuel Márquez de León and Paseo de los Héroes, according to Televisa, which cited Tijuana Police Chief Mario Martinez. Minutes after the fight, the suspects drove to the border crossing where they struck more than 15 vehicles waiting to cross into the United States and ran over 15 vendors, the news agency reported. RELATED: Witness to U.S.-Mexico border crash describes chaos in TijuanaFour people were injured, including one with severe injuries, Martinez told Televisa. The suspects were a man and woman, possibly American, Televisa report. The two were arrested and taken to the hospital. There was no word on a possible motive for the crash, or whether the suspects were under the influence.WATCH: Tijuana hotel near Las Americas Outlets explodes, injuring fourU.S. Customs and Border Protection told 10News they managed traffic on the U.S. side of the border during the incident. 1228

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