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SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906

SAN DIEGO (KGTV) — TwitchCon guests in San Diego for a weekend of gaming won't be celebrating the three-day convention with at least one headliner.Rapper Lil Nas X suddenly dropped out of TwitchCon's annual convention party set for Saturday night at Petco Park. The musician announced on Twitter he was canceling his performance to take some time off."It’s been a wild last 7 months and im ready to take a little time off. sorry to everyone attending twitchcon or the sandbox music festival, i will not be there. i love u guys and will make it up to you some way," the 20-year-old rapper tweeted.RELATED: Gaming, video streaming unite as TwitchCon returns to San DiegoLil Nas X was scheduled to perform alongside Blink-182, Au/Ra, Y2k, and Madeon. Those bands are still scheduled to perform at the streaming platform's convention.The end of the convention party is the convention's send off, treating attendees to performances by major music artists. The sold-out convention runs through Sunday at the San Diego Convention Center.Lil Nas X has seen an early climb to the top of the charts in 2019. His single "Old Town Road" topped the Billboard Hot 100 chart for 19 weeks to become the longest-running song in the chart's history. This month, his single "Panini" and album "7 EP" both went platinum.While the rapper said he would "make it up some way" to fans, no further details were given. 1400

SAN DIEGO (KGTV) - Summer is just around the corner, which means it’s time for family movie nights in the park! The 2018 Summer Movies in the Park series will kick off next Friday with a viewing of Coco at Waterfront Park.The event series is a great option for a family-friendly night out--- it offers games, giveaways, music and activities before the sun goes down. After sunset, you and your family can settle into your chairs and blankets to watch a movie under the stars.Movies are rated G through PG-13. This year’s Summer Movies in the Park is bigger than ever, with 151 movies showing at dozens of parks across the county. All screenings are free and open to the public.Movies include new hits, like “Star Wars: The Last Jedi” and “Black Panther,” as well as classics like “The Princess Bride” and “Back to the Future.” Be sure to check out the movie calendar for a complete schedule.San Diego County Parks and Recreation and sponsor cities began the series in 2007 as a “take back our parks” initiative. The movie nights were created to give San Diego residents a reason to visit their local parks for free and safe evening events, as well as discouraging inappropriate after-hours park use and loitering.This is the eleventh season of Summer Movies in the Park. This season, presented by Sharp Rees-Stealy Medical Centers, will run through late October.Details:Cost: FreeWhen: Friday, May 25 6 p.m. – 10 p.m. The move will start 15 minutes after sunset.Where: Waterfront Park, 1600 Pacific Hwy, San Diego, CA 92101  1547

SAN DIEGO (KGTV) -- Video taken Tuesday shows people climbing on top of the border fence near Friendship Park as the migrant caravan approaches.According to a Border Patrol spokesperson, agents are keeping watch on the U.S. side of the park, but aren’t aware of anyone climbing all the way over onto the U.S. side of the beach.Border Patrol says it’s technically not legal for people to sit on the fence because it’s on U.S. soil, but no arrests are being made at this time.RELATED: CBP closing lanes in San Ysidro, Otay Mesa as migrant caravan approachesIt’s unclear whether or not the group is with the migrant caravan.The incident comes as U.S. Customs and Border Protection announced the closure of several northbound border lanes in San Ysidro and Otay Mesa.The closures are expected to cause delays. 818

SAN DIEGO (KGTV) -- You've got the chance to start the new year right, with free Miranda Lambert tickets! Interested? Here's how you win:WATCH: 10NEWSWHEN: Wednesday, November 8 at 11 p.m., after the Country Music Awards on ABC.HOW: Watch to win. A cue to call will pop up on your screen, giving you the number you need to call for your chance at the tickets.See you at 11 p.m., San Diego!*The CMAs start tonight at 8 p.m. 431

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