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With over 160 vaccines in development, the race to defeat COVID-19 continues.A California company hopes to deliver its vaccine to your mailbox; one that is pain-free and doesn't require a needle and syringe."One of the things I wanted to do was make vaccines more patient-friendly, so they don't hurt and you're not afraid to take them," said Dr. Dan Henderson, a virologist and the CEO of Verndari, Inc.The biopharmaceutical company is based in Napa, California. Dr. Henderson originally came to the wine country to retire but stepped back into the lab during the Ebola crisis. He says some adults avoid vaccines because of a fear of needles, so Verndari set out to do something different. They created the VaxiPatch, a single-dose vaccination kit that uses a dermal patch with a metal microneedle array to deliver vaccines. Once applied, the person wears the patch like a Band-Aid for five minutes. The vaccine uses the COVID-19 "spike" protein that enables the virus to infect human cells and works to enhance a person's immune person.Unlike traditional vaccines, the patch doesn't need to be refrigerated, which Henderson says would make it easier and cheaper to send to developing countries. The company initially set out to make a flu vaccine but switched gears during the pandemic; they continue to adapt to the world's changing needs. "Now, for the First World, it's a shelter-in-place vaccine," said Henderson.They're working with the FDA to see if it could be mailed to your home. The vaccine would leave a temporary blue mark so the patient could take a photo and send it to their health care provider as proof of vaccination. In collaboration with the UC Davis, they've begun clinical trials in animals. Dr. Henderson says so far the results are promising.Other researchers are also working on getting a patch like this on people's arms.Scientists at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center have created a fingertip-sized skin patch that is also showing promising results in animal testing. Verndari hopes to test its vaccine in humans in the fall, and if all goes well, it could be made available to the public early next year. Dr. Henderson believes they could manufacture about 20 million doses a month. "It would mean a lot because it's important to me to make a contribution and a contribution like that, to me, is priceless." 2408
????Alert ????We received reports that an unknown party is purposefully spreading misinformation via robocalls in Flint in an attempt to confuse voters there. I want to ensure everyone who plans to vote in person understands you *must be in line to do so by 8 p.m. today.* (1/3)— Jocelyn Benson (@JocelynBenson) November 3, 2020 336

With the midterm elections less than a month away, President Donald Trump is back on the campaign trail, trying to rally Republicans to vote.To boost turnout, the president is making the election about him.“I'm not on the ballot, but in a certain way I’m on the ballot, so please go out and vote,” Trump said at a recent rally. “And I’m not on the ticket, but I am on the ticket, because this is also a referendum about me. Get out and vote. I want you to vote. Pretend I’m on the ballot.”The president's calendar is stacked with appearances, with four just this week. Not even Hurricane Michael, one of the strongest storms to ever hit the U.S., stopped President Trump from attending a campaign rally last night.The president defended his decision to go to the rally, saying people waited in line to see him.“What are you going to do? Tell thousands of people that have been waiting there all night that we're not coming? That's not fair either,” Trump said.Trump did, however, call it "wrong" when President Obama attended a campaign event back in 2012 when a smaller hurricane hit the east coast.But with control of Congress up for grabs, right now the stakes are high for the president. Republicans keeping the majority in the Senate is incredibly important for the president's agenda. The idea of keeping a majority in the House would be important personally, considering the dynamics of impeachment. 1419
between protesters and police at the Manhattan Bridge between Brooklyn and Manhattan Tuesday night.The crowd of demonstrators who were peacefully marching from Brooklyn to Manhattan were crossing the Manhattan Bridge after the city's 8 p.m. curfew. Police stopped marchers from entering Manhattan the island when police barricaded the bridge at its exit.According to social media reports, protesters became "stuck" on the bridge, as police also blockaded the Brooklyn side of the bridge.As the night went on, aerial footage showed the large group of peaceful protesters begin to cross the bridge back toward Brooklyn. 619
You may have heard the phrase lately, 'the pandemic isn't over just because you're over it,' and that is because a lot of people across the country are feeling COVID fatigue.We've been doing the work, wearing masks, social-distancing and upending nearly every aspect of our lives, but with the end of the pandemic still unclear, many are left feeling defeated and burned out," Best-selling author and clinical psychologist Dr. Wayne Pernell said. "We are running this marathon and someone goes, 'we moved the finish line, keep going.'"In fact, he said whatever you are feeling is normal, but it is definitely understandable to feel, for lack of a better term, completely over it. So, how do we cope with this constant change and uncertainty? For starters, Dr. Pernell said do something as simple as reminding yourself of the things you have grown to like about this new normal."We really need to take time for ourselves and to recognize that there are some things we like about the new schedule. My commute has been reduced to about 30 seconds," Pernell chuckled.Other examples of this are getting to spend time with your kids or having lunch every day with a significant other, things that would not have been possible without current restrictions.Dr. Pernell also said to give yourself a break and recognize when others need it too."We all get to this place of a little irritation or a little 'I've had enough.' Allow that, recognize it, acknowledge it and don't try and make it better," he said.Keeping with the trend of thinking positively, Dr. Pernell said he sees this as a time to really hone the skills we are gaining. He said given what we are all going through, we will be more resilient and courageous, things he said will serve us well going forward."Every day we are filled with uncertainty," Dr. Pernell said. "Every day we wake up and we don't know what today might hold... if there are new impositions on us or new rules."Of course, number one, Dr. Pernell said to remember that this will end. Eventually."Recognize also that just like a foggy day or a rainy day, just realize it's not foggy or rainy all the time, forever and ever and ever. That this does burn out, that there is sunshine," Dr. Pernell said.This story was originally reported by Claire Crouch at WLEX. 2293
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