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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.
SHIJIAZHUANG, Dec. 3 (Xinhua) -- More than 3.48 million people in rural areas of north China's Hebei Province have been given access to safe drinking water this year, a local official said Saturday.Authorities in the province have invested more than 1.7 billion yuan (270 million U.S. dollars) so far in 2011 in building drinking water infrastructure, said Liang Jianyi, deputy director of the Hebei Provincial Department of Water and Resources.More than 32 million rural people in Hebei, especially in mountainous and coastal areas, had long suffered from unsafe water, with problems including high fluorine and alkaline contents, Liang said.From 2005 to 2010, the provincial authorities put almost 6 billion yuan into providing safe drinking water for 13 million rural residents, he added.
SAN FRANCISCO, Dec. 9 (Xinhua) -- Apple on Friday suffered a major setback in its global patent war, as a German court ruled over its copyright infringement battle in favor of Motorola Mobility.The German court ruled that Apple's iPhone and iPad infringe a Motorola patent and issued an injunction banning the import of iPhones and 3G-capable iPads into Germany.The dispute, one of Apple's several patent lawsuits around the world, is over a Motorola patent essential to GPRS. Motorola has been negotiating with Apple over licensing terms and conditions since 2007, and it will continue its efforts to resolve its global patent dispute as soon as practicable, said Motorola Mobility in a statement on Friday."We're going to appeal the court's ruling right away. Holiday shoppers in Germany should have no problem finding the iPad or iPhone they want," an Apple spokesman told tech news site AllThingsD.Apple is not too concerned about losing out in the Christmas shopping season as it has plenty of iPhones and iPads in Germany already, AllThingsD cited unidentified sources as saying.The ruling is against Apple's European sales company and only impacts its products sold in Germany. The German court also ruled that Motorola is entitled to a damages award.Apple can appeal the ruling to a higher court and request a stay of the injunction, according to a blog post of Florian Mueller, a U.S. patent expert who has been closely following patent lawsuits in the mobile industry.Mueller said should Apple make the appeal but the court declines the stay, Motorola must post a 100 million euro (around 134 million U.S. dollars) bond before the court will enforce the injunction.In August, Apple also filed a suit in Germany over the design of Motorola's tablet Xoom, which runs Google's Android system. But Apple did not make it clear whether it will seek to block the sales of Xoom in Europe.Also on Friday, Samsung won an appeal from the Australian High Court overturning a previous Apple victory that effectively banned Samsung from selling its Galaxy Tab in Australia.Based on claims of infringing Apple's patents, the Cupertino, California-based tech giant has been seeking court order to block Samsung's Galaxy line of mobile devices around the world.A German court issued an injunction in August, blocking Samsung from selling its Galaxy Tab 10.1 tablets across all European Union members, except for the Netherlands.On Thursday, Apple said it will appeal a San Jose, California judge's refusal to ban sales of Samsung 4G smartphones and Galaxy Tab 10.1 tablets in the United States.
SHANGHAI, Jan. 11 (Xinhua) -- China has allowed the Bank of East Asia (BEA) to issue yuan-denominated bonds in Hong Kong for a second time, about three years after it became the first foreign-invested bank to make a yuan bond issuance, the bank said Wednesday.BEA China Ltd, a wholly-owned subsidiary of the BEA, was given the approval by the National Development and Reform Commission of China to issue yuan bonds in Hong Kong, it said.Details on the amounts and timing of the offerings weren't available. In 2009, in a major landmark, the BEA issued its first yuan bonds in Hong Kong in an aggregate principal amount of 4 billion yuan (630 million U.S. dollars).The BEA was among the first foreign-invested banks to be given the green light to issue yuan-denominated bonds in Hong Kong, a move analysts say will bolster the international influence of the Chinese currency, also known as renminbi.Sun Minjie, deputy head of BEA China, said the second bond issuance will give the bank stable access to capital, improve its debt portfolio, and support its development on the Chinese mainland.
BEIJING, Nov. 20 (Xinhua) -- Chinese Vice Premier Li Keqiang visited HIV/AIDS medical personnel, volunteers of non-government organizations (NGOs), and people living with HIV ahead of the World AIDS Day which falls on Dec. 1.In the voluntary testing clinic of the Beijing Diseases Prevention and Control Center (CDC), Li said counseling and testing are crucial to the early detection and early treatment of HIV/AIDS, and encouraged the clinic staff to work hard on the very front-line of HIV prevention and control.While visiting NGOs situated in the Beijing CDC, Li greeted people living with HIV and volunteers, shaking hands with them. He recognized the role of NGOs in keeping the disease at bay, particularly in terms of HIV/ AIDS awareness education and intervention.Chinese Vice Premier Li Keqiang (C) talks with a HIV/AIDS medical personnel as he visits the voluntary testing clinic of the Beijing Diseases Prevention and Control Center (CDC), in Beijing, China, Nov. 18, 2011.Li said HIV prevention and control is a systemic project that takes the entire society to carry out, calling for establishing a mechanism to involve "social forces" into HIV prevention and control.Li asked health authorities at all levels to keep close contact with HIV-related NGOs, providing assistance needed to these organizations and their volunteers."Care, respect and assistance are the best pain relievers for people living with HIV," Li said, calling upon the entire society to pay greater attention and care to this group of people.