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The Santa Clarita, California-based cruise line said in a statement that the American woman died early Tuesday aboard the Royal Princess. 137
The trial points to the retinas in a patient’s eyes as possible clues to diagnosing Alzheimer's using equipment that’s already standard in many optometry and opthalmology offices. Doctors are hopeful the new detection could mean diagnosing the disease up to 20 years before symptoms start. The clinical trials are crucial for families like the Lees. Kristine Lee watched as Alzheimer’s slowly stole her grandma’s memory, slipping away one phone call at a time. “We’d call and say ‘Hi Grandma! We love you hope you’re doing well.’ My aunt would say, ‘She heard your voice. She smiled,’ but eventually that progressed,” Lee said.Lee lost her grandma by the time she turned 18, but her death soon shaped her entire career when she joined the Alzheimer’s Association and started heading up races in an effort to raise money in search for a cure. “I was like this is where I belong,” Lee said with a smile.Dr. Stuart Sinoff, a neurology physician at BayCare knows that pain too. “I lost my mother to Alzheimer's in February,” he said softly. Coincidentally, her diagnosis happened years after Sinoff began researching new ways to detect Alzheimer’s . “My mom was not clearly an Alzheimer’s patient at that time so that kind of happened to come along because we’re all touched by this condition,” Sinoff explained.Now, Sinoff and doctors from Butler Hospital in Providence, Rhode Island, are about to launch a million clinical trial to study retinas to detect Alzheimer’s years before memory loss begins. “When you leave your keys, when you’re wondering what your shopping list was, is it really just the relatively expected mild change in aging or do you have an important neurodegenerative disease that might be the beginning of something really disastrous? This research will pave the way for patients to find out sooner,” Sinoff added. The test is not only faster but costs a fraction of standard diagnosis. The retina scan is estimated to cost around , compared to ,500 for the average PET scan. 2003

The time has come to make clear to the American people and to this President that his train of injuries to our Constitution must be brought to an end through impeachment, he said. 179
The study asked 116,632 adults between the age of 35 and 70 from 21 countries about their sleeping habits. Participants were then followed up over an average of 7.8 years.The team found that for every 1,000 people sleeping the recommended six to eight hours per night, 7.8 developed cardiovascular disease or died each year. This rose to 9.4 in people who slept six or fewer hours a night.Francesco Cappuccio, professor of cardiovascular medicine and epidemiology at Warwick University, who was not involved in this study, has done several studies into sleep and its effect on our health. He says that a lack of sleep is "definitely associated with an increased risk of death.""If you sleep less for a long time you are more prone to develop chronic disease," Cappuccio said, adding that short sleep duration has been shown to increase high blood pressure, obesity and diabetes.However, the findings for those who underslept were not found to be statistically significant, and the greatest risk was instead seen among those who overslept.For those sleeping eight to nine hours, 8.4 per 1,000 people developed cardiovascular disease or died each year. This rose even further in those sleeping nine to 10 hours (10.4 per 1,000) and again among those sleeping more than 10 hours (14.8 per 1,000).This equates to an increase in risk of a 5%, 17% and 41%, respectively, compared with people who slept the recommended amount of hours.But Wang pointed out that too much sleep could be a marker for other causes of cardiovascular diseases and death.Cappuccio agreed, adding that "it's not that long sleep causes death or ill health" but that ill health will cause you to sleep more.Cappuccio mentioned that people who have an undetected illness may suffer from an extension of sleep. If someone has an underlying cancer, for example, they will be more fatigued and debilitated and will tend to sleep longer.The study's main takeaway is that the optimal duration of estimated sleep is six to eight hours per day for adults, Wang explained.It is "very important to point out that there are some very simple things you can do to help you sleep better at night," Ward said, advising people to avoid caffeine in the afternoon or evenings, as well as alcohol and nicotine, which can disrupt sleep patterns. Exercise and a balanced diet can help, she added. 2352
The woman claimed the three men were forcing her to have sex when another naked man joined them. He joined the three men and woman and forced her to perform oral sex. 166
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