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A New York appeals court has cleared the way for a publisher to distribute a tell-all book by President Donald Trump's niece over the objections of the president's brother. The New York State Supreme Court Appellate Division issued the written decision late Wednesday. The appeals court lifted a restraint that a judge put on Simon & Schuster that sought to block its distribution. But it left in place restraints against Mary Trump. She's the author of “Too Much and Never Enough: How My Family Created the World’s Most Dangerous Man.” The publisher, Simon & Schuster, and a lawyer for Mary Trump praised the ruling. An email seeking comment was sent to a lawyer for Robert Trump, who sued Mary Trump. 718

A third leading candidate COVID-19 vaccine has entered a final stage of human testing in the United States. AstraZeneca announced Monday its potential COVID-19 vaccine has entered final trials in the U.S. to test the effectiveness and safety of the product. The Cambridge, England-based company said the trial will involve up to 30,000 adults from various racial, ethnic and geographic groups. The potential vaccine was invented by the University of Oxford and an associated company, Vaccitech.AstraZeneca said development of the vaccine known as AZD1222 is moving ahead globally with late-stage trials in the U.K., Brazil and South Africa. Further trials are planned in Japan and Russia.“To have just one vaccine enter the final stage of trials eight months after discovering a virus would be a remarkable achievement; to have three at that point with more on the way is extraordinary,” Health and Human Services Secretary Alex Azar said in a statement.Two other vaccine candidates began final testing this summer in tens of thousands of people in the U.S. One was created by the National Institutes of Health and manufactured by Moderna Inc., and the other developed by Pfizer Inc. and Germany’s BioNTech. 1215

A suspected suicide bombing at a wedding hall in the Afghan capital, Kabul, has killed 40 people and injured dozens more, officials say.The blast ripped through a venue near the city's international airport, where a gathering of religious scholars was taking place, the Afghan interior ministry said. The blast occurred around 6:15 p.m. local time, police said.It was likely caused by a suicide attack, according to Najib Danish, spokesman for the Afghan Ministry of the Interior. The gathering was being held to mark the birthday of the Prophet Mohammed, he said.At least 60 people were injured, the health ministry reported.The security situation in Kabul has deteriorated sharply in the past year.In August, at least 34 people were killed in an attack which targeted an education center. Among the victims were thought to be dozens of teenagers studying English.Then in September, 20 people, including two journalists, were killed in twin bomb attacks on a wrestling club for which ISIS claimed responsibility. The second blast was detonated after emergency services, journalists and police arrived at the scene.In July, the UN released a report stating the number of Afghan civilians killed in the first six months of 2018 had reached a record high. Almost 1,700 civilians were killed from January 1 to June 30, a total higher than at any comparable time over the last 10 years, according to the UN. 1411

A record number of unaccompanied immigrant children, about 14,000, are currently in US custody, a Health and Human Services spokesman said Friday.The spokesman, Mark Weber, said the additional requirements put in place by the Trump administration to "reduce risk and increase safety" for immigrant children contributed to the high number."We are taking all possible steps to protect children in an environment with many bad actors," Weber said. "We are balancing speed with safety and will err on the side of safety."The Houston Chronicle earlier reported the figure.Last spring, the Trump administration heightened scrutiny of adults coming forward to take care of the immigrant children, and Immigrations and Customs Enforcement now conducts exhaustive screenings of the adults. But many of them are undocumented themselves and fearful of ICE obtaining their information.These Trump administration policies are likely keeping these children in custody.Lawsuits have also accused the administration of extending children's stays, including allegedly holding them intentionally until they turn 18 and are eligible for stricter adult detention. Many of the children do have a legal right to stay in the US, but the legal process can take years.Weber said the high number was also due to the 50,000 Department of Homeland Security referrals of unaccompanied children this year, which he said is the third-highest annual total. DHS referred 59,170 unaccompanied children to HHS in fiscal year 2016, according to a HHS fact sheet, and 40,810 in fiscal year 2017.The number of children in custody changes daily because of referrals by DHS and HHS releases of children to sponsors, Weber said.Most of these children arrived in the US unaccompanied. Children separated under Trump's so-called "zero tolerance" policy account for less than 200 of the reported 14,000. CNN reported earlier this month there are still 171 children separated from their families, four months after a judge ordered the US government to reunite the undocumented immigrant families it had split up at the border, according to court documents.In 2016, the monthly average of the number of children in HHS's care ranged from just over 4,000 to over 9,000. 2230

A storm system causing severe weather Sunday along the Gulf Coast is forecast to move off the East Coast, turn into a nor'easter and threaten the Northeastern United States on Monday night into Tuesday.The storm's exact path remains a bit uncertain, but the system will bring precipitation and wind in what will be the third significant winter storm in the past 10 days.A winter storm watch is in effect for 8.5 million people in New England, including residents of Boston and Portland, Maine. The National Weather Service Boston estimated 6 to 8 inches of snow for parts of Massachusetts, Rhode Island and Connecticut.New York, Philadelphia and Washington are only under a hazardous weather outlook at this time. The next forecast update will come at 8 p.m. on Sunday.The American model forecasts heavy snowfall for areas of New England and upstate New York, whereas the European model shows less snowfall. Still, both models agree there will be more snow on the way for the Northeast.If the nor'easter tracks closer to the coast, then stronger winds and coastal flooding may become issues as well.Last weekend, a powerful nor'easter that morphed into a "bomb cyclone" slammed much of the Northeast with heavy snow and rain, hurricane-force wind gusts, and significant coastal flooding. The storm left six people dead from falling trees, and about 900,000 people lost electrical power.As residents were still digging out from that snow, a second storm hit the Northeast late last week. The storm dropped heavy, wet snow in areas west of Interstate 95, leaving feet of snow in some areas. One 88-year-old woman died Wednesday when a tree fell and struck her in Suffern, in southern New York, police said.This winter's snowfall totals so far sit around the annual average at this point for the major Northeast hubs of Boston, New York and Philadelphia, according to the National Weather Service. 1937